Jan B. Hoek
Jan B. Hoek
Adresse e-mail validée de jefferson.edu
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Quantification of short term signaling by the epidermal growth factor receptor
BN Kholodenko, OV Demin, G Moehren, JB Hoek
Journal of Biological Chemistry 274 (42), 30169-30181, 1999
7281999
Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades
NI Markevich, JB Hoek, BN Kholodenko
The Journal of cell biology 164 (3), 353-359, 2004
7232004
Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis
JG Pastorino, N Shulga, JB Hoek
Journal of Biological Chemistry 277 (9), 7610-7618, 2002
6772002
PANTHER: a browsable database of gene products organized by biological function, using curated protein family and subfamily classification
PD Thomas, A Kejariwal, MJ Campbell, H Mi, K Diemer, N Guo, I Ladunga, ...
Nucleic acids research 31 (1), 334-341, 2003
6142003
Ethanol, oxidative stress, and cytokine-induced liver cell injury
JB Hoek, JG Pastorino
Alcohol 27 (1), 63-68, 2002
5572002
Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion
KD Chavin, SQ Yang, HZ Lin, J Chatham, VP Chacko, JB Hoek, ...
Journal of Biological Chemistry 274 (9), 5692-5700, 1999
5321999
Untangling the wires: a strategy to trace functional interactions in signaling and gene networks
BN Kholodenko, A Kiyatkin, FJ Bruggeman, E Sontag, HV Westerhoff, ...
Proceedings of the National Academy of Sciences 99 (20), 12841-12846, 2002
4492002
Alcohol and mitochondria: a dysfunctional relationship
JB Hoek, A Cahill, JG Pastorino
Gastroenterology 122 (7), 2049-2063, 2002
4382002
Activation of glycogen synthase kinase 3β disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy …
JG Pastorino, JB Hoek, N Shulga
Cancer research 65 (22), 10545-10554, 2005
4142005
Role of calcium in the hormonal regulation of liver metabolism
JR Williamson, RH Cooper, JB Hoek
Biochimica et Biophysica Acta (BBA)-Reviews on Bioenergetics 639 (3-4), 243-295, 1981
3781981
Physiological roles of nicotinamide nucleotide transhydrogenase
JB Hoek, J Rydström
Biochemical Journal 254 (1), 1-10, 1988
3541988
Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore
JG Pastorino, M Tafani, RJ Rothman, A Marcineviciute, JB Hoek, ...
Journal of Biological Chemistry 274 (44), 31734-31739, 1999
3511999
Regulation of hexokinase binding to VDAC
JG Pastorino, JB Hoek
Journal of bioenergetics and biomembranes 40 (3), 171-182, 2008
3262008
Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition.
JG Pastorino, JW Snyder, A Serroni, JB Hoek, JL Farber
Journal of Biological Chemistry 268 (19), 13791-13798, 1993
3191993
Ligand‐dependent responses of the ErbB signaling network: experimental and modeling analyses
MR Birtwistle, M Hatakeyama, N Yumoto, BA Ogunnaike, JB Hoek, ...
Molecular systems biology 3 (1), 144, 2007
2732007
Hexokinase II: the integration of energy metabolism and control of apoptosis
JG Pastorino, JB Hoek
Current medicinal chemistry 10 (16), 1535-1551, 2003
2512003
Determination of the mitochondrial protonmotive force in isolated hepatocytes.
JB Hoek, DG Nicholls, JR Williamson
Journal of Biological Chemistry 255 (4), 1458-1464, 1980
2501980
Systems‐level interactions between insulin–EGF networks amplify mitogenic signaling
N Borisov, E Aksamitiene, A Kiyatkin, S Legewie, J Berkhout, T Maiwald, ...
Molecular systems biology 5 (1), 256, 2009
2332009
Why cytoplasmic signalling proteins should be recruited to cell membranes
BN Kholodenko, JB Hoek, HV Westerhoff
Trends in cell biology 10 (5), 173-178, 2000
2312000
Ethanol potentiates tumor necrosis factor‐α cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition
JG Pastorino, JB Hoek
Hepatology 31 (5), 1141-1152, 2000
2072000
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