Jan B. Hoek
Jan B. Hoek
Adresse e-mail validée de jefferson.edu
Citée par
Citée par
Quantification of short term signaling by the epidermal growth factor receptor
BN Kholodenko, OV Demin, G Moehren, JB Hoek
Journal of Biological Chemistry 274 (42), 30169-30181, 1999
Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades
NI Markevich, JB Hoek, BN Kholodenko
The Journal of cell biology 164 (3), 353-359, 2004
Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis
JG Pastorino, N Shulga, JB Hoek
Journal of Biological Chemistry 277 (9), 7610-7618, 2002
PANTHER: a browsable database of gene products organized by biological function, using curated protein family and subfamily classification
PD Thomas, A Kejariwal, MJ Campbell, H Mi, K Diemer, N Guo, I Ladunga, ...
Nucleic acids research 31 (1), 334-341, 2003
Ethanol, oxidative stress, and cytokine-induced liver cell injury
JB Hoek, JG Pastorino
Alcohol 27 (1), 63-68, 2002
Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion
KD Chavin, SQ Yang, HZ Lin, J Chatham, VP Chacko, JB Hoek, ...
Journal of Biological Chemistry 274 (9), 5692-5700, 1999
Untangling the wires: a strategy to trace functional interactions in signaling and gene networks
BN Kholodenko, A Kiyatkin, FJ Bruggeman, E Sontag, HV Westerhoff, ...
Proceedings of the National Academy of Sciences 99 (20), 12841-12846, 2002
Alcohol and mitochondria: a dysfunctional relationship
JB Hoek, A Cahill, JG Pastorino
Gastroenterology 122 (7), 2049-2063, 2002
Activation of glycogen synthase kinase 3β disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy …
JG Pastorino, JB Hoek, N Shulga
Cancer research 65 (22), 10545-10554, 2005
Role of calcium in the hormonal regulation of liver metabolism
JR Williamson, RH Cooper, JB Hoek
Biochimica et Biophysica Acta (BBA)-Reviews on Bioenergetics 639 (3-4), 243-295, 1981
Physiological roles of nicotinamide nucleotide transhydrogenase
JB Hoek, J Rydström
Biochemical Journal 254 (1), 1-10, 1988
Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore
JG Pastorino, M Tafani, RJ Rothman, A Marcineviciute, JB Hoek, ...
Journal of Biological Chemistry 274 (44), 31734-31739, 1999
Regulation of hexokinase binding to VDAC
JG Pastorino, JB Hoek
Journal of bioenergetics and biomembranes 40 (3), 171-182, 2008
Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition.
JG Pastorino, JW Snyder, A Serroni, JB Hoek, JL Farber
Journal of Biological Chemistry 268 (19), 13791-13798, 1993
Ligand‐dependent responses of the ErbB signaling network: experimental and modeling analyses
MR Birtwistle, M Hatakeyama, N Yumoto, BA Ogunnaike, JB Hoek, ...
Molecular systems biology 3 (1), 144, 2007
Hexokinase II: the integration of energy metabolism and control of apoptosis
JG Pastorino, JB Hoek
Current medicinal chemistry 10 (16), 1535-1551, 2003
Determination of the mitochondrial protonmotive force in isolated hepatocytes.
JB Hoek, DG Nicholls, JR Williamson
Journal of Biological Chemistry 255 (4), 1458-1464, 1980
Systems‐level interactions between insulin–EGF networks amplify mitogenic signaling
N Borisov, E Aksamitiene, A Kiyatkin, S Legewie, J Berkhout, T Maiwald, ...
Molecular systems biology 5 (1), 256, 2009
Why cytoplasmic signalling proteins should be recruited to cell membranes
BN Kholodenko, JB Hoek, HV Westerhoff
Trends in cell biology 10 (5), 173-178, 2000
Ethanol potentiates tumor necrosis factor‐α cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition
JG Pastorino, JB Hoek
Hepatology 31 (5), 1141-1152, 2000
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