| Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis JG Pastorino, N Shulga, JB Hoek Journal of Biological Chemistry 277 (9), 7610-7618, 2002 | 831 | 2002 |
| Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades NI Markevich, JB Hoek, BN Kholodenko The Journal of cell biology 164 (3), 353-359, 2004 | 828 | 2004 |
| Quantification of short term signaling by the epidermal growth factor receptor BN Kholodenko, OV Demin, G Moehren, JB Hoek Journal of Biological Chemistry 274 (42), 30169-30181, 1999 | 800 | 1999 |
| Ethanol, oxidative stress, and cytokine-induced liver cell injury JB Hoek, JG Pastorino Alcohol 27 (1), 63-68, 2002 | 633 | 2002 |
| Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion KD Chavin, SQ Yang, HZ Lin, J Chatham, VP Chacko, JB Hoek, ... Journal of Biological Chemistry 274 (9), 5692-5700, 1999 | 596 | 1999 |
| Alcohol and mitochondria: a dysfunctional relationship JB Hoek, A Cahill, JG Pastorino Gastroenterology 122 (7), 2049-2063, 2002 | 572 | 2002 |
| Untangling the wires: a strategy to trace functional interactions in signaling and gene networks BN Kholodenko, A Kiyatkin, FJ Bruggeman, E Sontag, HV Westerhoff, ... Proceedings of the National Academy of Sciences 99 (20), 12841-12846, 2002 | 498 | 2002 |
| Activation of glycogen synthase kinase 3β disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy … JG Pastorino, JB Hoek, N Shulga Cancer research 65 (22), 10545-10554, 2005 | 482 | 2005 |
| Regulation of hexokinase binding to VDAC JG Pastorino, JB Hoek Journal of bioenergetics and biomembranes 40, 171-182, 2008 | 451 | 2008 |
| Role of calcium in the hormonal regulation of liver metabolism JR Williamson, RH Cooper, JB Hoek Biochimica et Biophysica Acta (BBA)-Reviews on Bioenergetics 639 (3-4), 243-295, 1981 | 423 | 1981 |
| Physiological roles of nicotinamide nucleotide transhydrogenase JB Hoek, J Rydström Biochemical Journal 254 (1), 1-10, 1988 | 414 | 1988 |
| Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore JG Pastorino, M Tafani, RJ Rothman, A Marcineviciute, JB Hoek, ... Journal of Biological Chemistry 274 (44), 31734-31739, 1999 | 371 | 1999 |
| Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition JG Pastorino, JW Snyder, A Serroni, JB Hoek, JL Farber Journal of Biological Chemistry 268 (19), 13791-13798, 1993 | 339 | 1993 |
| Hexokinase II: the integration of energy metabolism and control of apoptosis JG Pastorino, JB Hoek Current medicinal chemistry 10 (16), 1535-1551, 2003 | 300 | 2003 |
| Ligand‐dependent responses of the ErbB signaling network: experimental and modeling analyses MR Birtwistle, M Hatakeyama, N Yumoto, BA Ogunnaike, JB Hoek, ... Molecular systems biology 3 (1), 144, 2007 | 296 | 2007 |
| Determination of the mitochondrial protonmotive force in isolated hepatocytes. JB Hoek, DG Nicholls, JR Williamson Journal of Biological Chemistry 255 (4), 1458-1464, 1980 | 293 | 1980 |
| Why cytoplasmic signalling proteins should be recruited to cell membranes BN Kholodenko, JB Hoek, HV Westerhoff Trends in cell biology 10 (5), 173-178, 2000 | 282 | 2000 |
| Systems‐level interactions between insulin–EGF networks amplify mitogenic signaling N Borisov, E Aksamitiene, A Kiyatkin, S Legewie, J Berkhout, T Maiwald, ... Molecular systems biology 5 (1), 256, 2009 | 270 | 2009 |
| Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops A Kiyatkin, E Aksamitiene, NI Markevich, NM Borisov, JB Hoek, ... Journal of biological chemistry 281 (29), 19925-19938, 2006 | 235 | 2006 |
| Ethanol potentiates tumor necrosis factor‐α cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition JG Pastorino, JB Hoek Hepatology 31 (5), 1141-1152, 2000 | 231 | 2000 |
