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John (Ioannis) Vakonakis
John (Ioannis) Vakonakis
Associate Professor in Structural Biology and Biophysics
Adresse e-mail validée de bioch.ox.ac.uk
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Structural basis of the 9-fold symmetry of centrioles
D Kitagawa, I Vakonakis, N Olieric, M Hilbert, D Keller, V Olieric, ...
Cell 144 (3), 364-375, 2011
4132011
The structure of an integrin/talin complex reveals the basis of inside‐out signal transduction
NJ Anthis, KL Wegener, F Ye, C Kim, BT Goult, ED Lowe, I Vakonakis, ...
The EMBO journal 28 (22), 3623-3632, 2009
3992009
Structure and function from the circadian clock protein KaiA of Synechococcus elongatus: a potential clock input mechanism
SB Williams, I Vakonakis, SS Golden, AC LiWang
Proceedings of the National Academy of Sciences 99 (24), 15357-15362, 2002
2482002
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ...
Cell Stem Cell 29 (2), 217-231. e8, 2022
1652022
An Integrin Phosphorylation Switch: THE EFFECT OF β3 INTEGRIN TAIL PHOSPHORYLATION ON DOK1 AND TALIN BINDING*♦
CL Oxley, NJ Anthis, ED Lowe, I Vakonakis, ID Campbell, L Wegener
Journal of biological chemistry 283 (9), 5420-5426, 2008
1502008
Latrophilin signaling links anterior-posterior tissue polarity and oriented cell divisions in the C. elegans embryo
T Langenhan, S Prömel, L Mestek, B Esmaeili, H Waller-Evans, C Hennig, ...
Developmental cell 17 (4), 494-504, 2009
1392009
The GPS motif is a molecular switch for bimodal activities of adhesion class G protein-coupled receptors
S Prömel, M Frickenhaus, S Hughes, L Mestek, D Staunton, A Woollard, ...
Cell reports 2 (2), 321-331, 2012
1382012
Structure of the C-terminal domain of the clock protein KaiA in complex with a KaiC-derived peptide: implications for KaiC regulation
I Vakonakis, AC LiWang
Proceedings of the National Academy of Sciences 101 (30), 10925-10930, 2004
1322004
Crystal structure of circadian clock protein KaiA from Synechococcus elongatus
S Ye, I Vakonakis, TR Ioerger, AC LiWang, JC Sacchettini
Journal of Biological Chemistry 279 (19), 20511-20518, 2004
1272004
Extracellular matrix: from atomic resolution to ultrastructure
I Vakonakis, ID Campbell
Current opinion in cell biology 19 (5), 578-583, 2007
1172007
A Plasmodium falciparum PHIST protein binds the virulence factor PfEMP1 and comigrates to knobs on the host cell surface
A Oberli, LM Slater, E Cutts, F Brand, E Mundwiler-Pachlatko, S Rusch, ...
The FASEB Journal 28 (10), 4420, 2014
1112014
Identification and structural analysis of type I collagen sites in complex with fibronectin fragments
MC Erat, DA Slatter, ED Lowe, CJ Millard, RW Farndale, ID Campbell, ...
Proceedings of the National Academy of Sciences 106 (11), 4195-4200, 2009
1022009
Interdomain association in fibronectin: insight into cryptic sites and fibrillogenesis
I Vakonakis, D Staunton, LM Rooney, ID Campbell
The EMBO journal 26 (10), 2575-2583, 2007
982007
Allosteric inhibition of the SARS‐CoV‐2 Main protease: insights from mass spectrometry based assays
TJ El‐Baba, CA Lutomski, AL Kantsadi, TR Malla, T John, V Mikhailov, ...
Angewandte Chemie International Edition 59 (52), 23544-23548, 2020
962020
Solution structure and sugar-binding mechanism of mouse latrophilin-1 RBL: a 7TM receptor-attached lectin-like domain
I Vakonakis, T Langenhan, S Prömel, A Russ, ID Campbell
Structure 16 (6), 944-953, 2008
872008
NMR structure of the KaiC-interacting C-terminal domain of KaiA, a circadian clock protein: implications for KaiA–KaiC interaction
I Vakonakis, J Sun, T Wu, A Holzenburg, SS Golden, AC LiWang
Proceedings of the National Academy of Sciences 101 (6), 1479-1484, 2004
852004
Structural analysis of the Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) intracellular domain reveals a conserved interaction epitope
C Mayer, L Slater, MC Erat, R Konrat, I Vakonakis
Journal of Biological Chemistry 287 (10), 7182-7189, 2012
802012
Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture
GN Hatzopoulos, MC Erat, E Cutts, KB Rogala, LM Slater, PJ Stansfeld, ...
Structure 21 (11), 2069-2077, 2013
792013
A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum–infected erythrocytes
JM Watermeyer, VL Hale, F Hackett, DK Clare, EE Cutts, I Vakonakis, ...
Blood, The Journal of the American Society of Hematology 127 (3), 343-351, 2016
772016
Structural analysis of collagen type I interactions with human fibronectin reveals a cooperative binding mode
MC Erat, B Sladek, ID Campbell, I Vakonakis
Journal of Biological Chemistry 288 (24), 17441-17450, 2013
712013
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