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Wei Keat Lim
Wei Keat Lim
Regeneron
Adresse e-mail validée de regeneron.com
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Année
The transcriptional network for mesenchymal transformation of brain tumours
MS Carro, WK Lim, MJ Alvarez, RJ Bollo, X Zhao, EY Snyder, EP Sulman, ...
Nature 463 (7279), 318-325, 2010
13652010
Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma
M Compagno, WK Lim, A Grunn, SV Nandula, M Brahmachary, Q Shen, ...
Nature 459 (7247), 717-721, 2009
12782009
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
T Palomero, WK Lim, DT Odom, ML Sulis, PJ Real, A Margolin, ...
Proceedings of the National Academy of Sciences 103 (48), 18261-18266, 2006
10252006
Atlas of the clinical genetics of human dilated cardiomyopathy
J Haas, KS Frese, B Peil, W Kloos, A Keller, R Nietsch, Z Feng, S Müller, ...
European heart journal 36 (18), 1123-1135, 2015
5652015
Reverse engineering cellular networks
AA Margolin, K Wang, WK Lim, M Kustagi, I Nemenman, A Califano
Nature protocols 1 (2), 662-671, 2006
4452006
A human B‐cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers
C Lefebvre, P Rajbhandari, MJ Alvarez, P Bandaru, WK Lim, M Sato, ...
Molecular systems biology 6 (1), 377, 2010
4312010
Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells
K Basso, M Saito, P Sumazin, AA Margolin, K Wang, WK Lim, Y Kitagawa, ...
Blood, The Journal of the American Society of Hematology 115 (5), 975-984, 2010
2982010
Genome-wide identification of post-translational modulators of transcription factor activity in human B cells
K Wang, M Saito, BC Bisikirska, MJ Alvarez, WK Lim, P Rajbhandari, ...
Nature biotechnology 27 (9), 829-837, 2009
2752009
Dual blockade of IL‐4 and IL‐13 with dupilumab, an IL‐4Rα antibody, is required to broadly inhibit type 2 inflammation
A Le Floc’h, J Allinne, K Nagashima, G Scott, D Birchard, S Asrat, Y Bai, ...
Allergy 75 (5), 1188-1204, 2020
2562020
A systems biology approach to prediction of oncogenes and molecular perturbation targets in B‐cell lymphomas
KM Mani, C Lefebvre, K Wang, WK Lim, K Basso, R Dalla‐Favera, ...
Molecular systems biology 4 (1), 169, 2008
2522008
Comparative analysis of microarray normalization procedures: effects on reverse engineering gene networks
WK Lim, K Wang, C Lefebvre, A Califano
Bioinformatics 23 (13), i282-i288, 2007
2412007
Gene expression profiling suggests primary central nervous system lymphomas to be derived from a late germinal center B cell
M Montesinos-Rongen, A Brunn, S Bentink, K Basso, WK Lim, W Klapper, ...
Leukemia 22 (2), 400-405, 2008
1892008
Dupilumab in adults and adolescents with eosinophilic esophagitis
ES Dellon, ME Rothenberg, MH Collins, I Hirano, M Chehade, ...
New England Journal of Medicine 387 (25), 2317-2330, 2022
1712022
The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain
X Zhao, D D'Arca, WK Lim, M Brahmachary, MS Carro, T Ludwig, ...
Developmental cell 17 (2), 210-221, 2009
1702009
Master regulators used as breast cancer metastasis classifier
WK Lim, E Lyashenko, A Califano
Biocomputing 2009, 504-515, 2009
1062009
IL-33 blockade affects mediators of persistence and exacerbation in a model of chronic airway inflammation
J Allinne, G Scott, WK Lim, D Birchard, JS Erjefält, C Sandén, LH Ben, ...
Journal of Allergy and Clinical Immunology 144 (6), 1624-1637. e10, 2019
842019
T‐cell lymphoblastic lymphoma shows differences and similarities with T‐cell acute lymphoblastic leukemia by genomic and gene expression analyses
K Basso, L Mussolin, A Lettieri, M Brahmachary, WK Lim, A Califano, ...
Genes, Chromosomes and Cancer 50 (12), 1063-1075, 2011
552011
A context-specific network of protein-DNA and protein-protein interactions reveals new regulatory motifs in human B cells
C Lefebvre, WK Lim, K Basso, RD Favera, A Califano
Systems Biology and Computational Proteomics: Joint RECOMB 2006 Satellite …, 2007
402007
Activin A does not drive post-traumatic heterotopic ossification
C Hwang, CA Pagani, N Das, S Marini, AK Huber, LQ Xie, J Jimenez, ...
Bone 138, 115473, 2020
282020
Enhanced IL-36R signaling promotes barrier impairment and inflammation in skin and intestine
Z Hovhannisyan, N Liu, S Khalil-Aguero, C Panea, J VanValkenburgh, ...
Science Immunology 5 (54), eaax1686, 2020
212020
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