| Single App knock-in mouse models of Alzheimer's disease T Saito, Y Matsuba, N Mihira, J Takano, P Nilsson, S Itohara, N Iwata, ... Nature neuroscience 17 (5), 661-663, 2014 | 1030 | 2014 |
| APP mouse models for Alzheimer's disease preclinical studies H Sasaguri, P Nilsson, S Hashimoto, K Nagata, T Saito, B De Strooper, ... The EMBO journal 36 (17), 2473-2487, 2017 | 694 | 2017 |
| ScaleS: an optical clearing palette for biological imaging H Hama, H Hioki, K Namiki, T Hoshida, H Kurokawa, F Ishidate, T Kaneko, ... Nature neuroscience 18 (10), 1518-1529, 2015 | 599 | 2015 |
| Amyloid β oligomers constrict human capillaries in Alzheimer’s disease via signaling to pericytes R Nortley, N Korte, P Izquierdo, C Hirunpattarasilp, A Mishra, ... Science 365 (6450), eaav9518, 2019 | 530 | 2019 |
| Aβ secretion and plaque formation depend on autophagy P Nilsson, K Loganathan, M Sekiguchi, Y Matsuba, K Hui, S Tsubuki, ... Cell reports 5 (1), 61-69, 2013 | 474 | 2013 |
| Somatostatin regulates brain amyloid β peptide Aβ42 through modulation of proteolytic degradation T Saito, N Iwata, S Tsubuki, Y Takaki, J Takano, SM Huang, T Suemoto, ... Nature medicine 11 (4), 434-439, 2005 | 455 | 2005 |
| Potent amyloidogenicity and pathogenicity of Aβ43 T Saito, T Suemoto, N Brouwers, K Sleegers, S Funamoto, N Mihira, ... Nature neuroscience 14 (8), 1023-1032, 2011 | 344 | 2011 |
| Domain-specific mutations in TGFB1 result in Camurati-Engelmann disease A Kinoshita, T Saito, H Tomita, Y Makita, K Yoshida, M Ghadami, ... Nature genetics 26 (1), 19-20, 2000 | 274 | 2000 |
| Cognitive deficits in single App knock-in mouse models A Masuda, Y Kobayashi, N Kogo, T Saito, TC Saido, S Itohara Neurobiology of learning and memory 135, 73-82, 2016 | 209 | 2016 |
| Neuronal store-operated calcium entry and mushroom spine loss in amyloid precursor protein knock-in mouse model of Alzheimer's disease H Zhang, L Wu, E Pchitskaya, O Zakharova, T Saito, T Saido, ... Journal of Neuroscience 35 (39), 13275-13286, 2015 | 203 | 2015 |
| An aberrant sugar modification of BACE 1 blocks its lysosomal targeting in A lzheimer's disease Y Kizuka, S Kitazume, R Fujinawa, T Saito, N Iwata, TC Saido, M Nakano, ... EMBO molecular medicine 7 (2), 175-189, 2015 | 171 | 2015 |
| Versatile whole-oragan/body staining and imaging based on electrolyte-gel properties of biological tissues. Susaki EA, Shimizu C, Kuno A, Tainaka K, Li X, Nishi K, Morishima K, Ono H ... Nature Communications 11, 1982, 2020 | 161 | 2020 |
| SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice Y Liu, A Cheng, YJ Li, Y Yang, Y Kishimoto, S Zhang, Y Wang, R Wan, ... Nature communications 10 (1), 1886, 2019 | 152 | 2019 |
| Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer's disease. Sobue A, Komine O, Hara Y, Endo F, Mizoguchi H, Watanabe S, Murayama S ... Acta Neuropathologica Communications 9, 1, 2021 | 151 | 2021 |
| Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone SA Purro, MA Farrow, J Linehan, T Nazari, DX Thomas, Z Chen, ... Nature 564 (7736), 415-419, 2018 | 150 | 2018 |
| Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation E Castillo, J Leon, G Mazzei, N Abolhassani, N Haruyama, T Saito, ... Scientific reports 7 (1), 17762, 2017 | 146 | 2017 |
| Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation. Saito T, Mihira N, Matsuba Y, Sasaguri H, Hashimoto S, Narasimhan S, Zhang B ... Journal of Biological Chemistry 294, 12754-12765, 2019 | 141 | 2019 |
| HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer’s disease K Fujita, K Motoki, K Tagawa, X Chen, H Hama, K Nakajima, H Homma, ... Scientific reports 6 (1), 31895, 2016 | 134 | 2016 |
| Familial Alzheimer’s disease mutations in presenilin generate amyloidogenic Aβ peptide seeds S Veugelen, T Saito, TC Saido, L Chávez-Gutiérrez, B De Strooper Neuron 90 (2), 410-416, 2016 | 123 | 2016 |
| Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model. Clayton K, Delpech JC, Herron S, Iwahara N, Ericsson M, Saito T, Saido TC ... Molecular Neurodegeneration 16, 18, 2021 | 118* | 2021 |
Bart De Stroopergewoon hoogleraar KU Leuven en onderzoeksdirecteur VIBAdresse e-mail validée de cme.vib-kuleuven.be
