Shawn C. Little
Shawn C. Little
Assistant Professor, Univ. Pennsylvania
Verified email at
TitleCited byYear
Precise developmental gene expression arises from globally stochastic transcriptional activity
SC Little, M Tikhonov, T Gregor
Cell 154 (4), 789-800, 2013
Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis
SC Little, MC Mullins
Nature cell biology 11 (5), 637, 2009
The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization
Q Shen, SC Little, M Xu, J Haupt, C Ast, T Katagiri, S Mundlos, ...
The Journal of clinical investigation 119 (11), 3462-3472, 2009
Analysis of the properties of spores of Bacillus subtilis prepared at different temperatures
E Melly, PC Genest, ME Gilmore, S Little, DL Popham, A Driks, P Setlow
Journal of applied microbiology 92 (6), 1105-1115, 2002
The formation of the Bicoid morphogen gradient requires protein movement from anteriorly localized mRNA
SC Little, G Tkačik, TB Kneeland, EF Wieschaus, T Gregor
PLoS biology 9 (3), e1000596, 2011
Extracellular modulation of BMP activity in patterning the dorsoventral axis
SC Little, MC Mullins
Birth Defects Research Part C: Embryo Today: Reviews 78 (3), 224-242, 2006
The pro-BMP activity of Twisted gastrulation is independent of BMP binding
M Oelgeschläger, B Reversade, J Larraín, S Little, MC Mullins, ...
Development 130 (17), 4047-4056, 2003
Functional analysis of the Bacillus subtilis morphogenetic spore coat protein CotE
S Little, A Driks
Molecular microbiology 42 (4), 1107-1120, 2001
Twisted gastrulation promotes BMP signaling in zebrafish dorsal-ventral axial patterning
SC Little, MC Mullins
Development 131 (23), 5825-5835, 2004
Independent and coordinate trafficking of single Drosophila germ plasm mRNAs
SC Little, KS Sinsimer, JJ Lee, EF Wieschaus, ER Gavis
Nature cell biology 17 (5), 558, 2015
Functional regions of the Bacillus subtilis spore coat morphogenetic protein CotE
T Bauer, S Little, AG Stöver, A Driks
Journal of bacteriology 181 (22), 7043-7051, 1999
The embryo as a laboratory: quantifying transcription in Drosophila
T Gregor, HG Garcia, SC Little
Trends in Genetics 30 (8), 364-375, 2014
Maternal origins of developmental reproducibility
MD Petkova, SC Little, F Liu, T Gregor
Current Biology 24 (11), 1283-1288, 2014
Diverse spatial expression patterns emerge from unified kinetics of transcriptional bursting
B Zoller, SC Little, T Gregor
Cell 175 (3), 835-847. e25, 2018
Shifting patterns: merging molecules, morphogens, motility, and methodology
SC Little, EF Wieschaus
Developmental cell 21 (1), 2-4, 2011
Only accessible information is useful: insights from gradient-mediated patterning
M Tikhonov, SC Little, T Gregor
Royal Society open science 2 (11), 150486, 2015
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques
J Petrovic, Y Zhou, M Fasolino, N Goldman, GW Schwartz, MR Mumbach, ...
Molecular cell 73 (6), 1174-1190. e12, 2019
Activation of BMP signaling by the FOP ACVR1 R206H mutation
Q Shen
J Bone Miner Res 22 (1), S43, 2007
Functional analysis of the morphogenetic spore coat Bacillus subtilis protein CotE
S Little, A Driks
MOLECULAR MICROBIOLOGY 42 (4), 1107-1120, 2001
Diverse spatial expression patterns emerge from common transcription bursting kinetics
B Zoller, SC Little, T Gregor
arXiv preprint arXiv:1712.08215, 2017
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