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Qi Hu
Qi Hu
Westlake University
Verified email at westlake.edu.cn
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Year
Structural basis of ultraviolet-B perception by UVR8
D Wu, Q Hu, Z Yan, W Chen, C Yan, X Huang, J Zhang, P Yang, H Deng, ...
Nature 484 (7393), 214-219, 2012
4712012
Atomic structure of the apoptosome: mechanism of cytochrome c-and dATP-mediated activation of Apaf-1
M Zhou, Y Li, Q Hu, X Bai, W Huang, C Yan, SHW Scheres, Y Shi
Genes & development 29 (22), 2349-2361, 2015
2432015
Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4
S Qi, Y Pang, Q Hu, Q Liu, H Li, Y Zhou, T He, Q Liang, Y Liu, X Yuan, ...
Cell 141 (3), 446-457, 2010
1852010
Structure and mechanism of the hexameric MecA–ClpC molecular machine
F Wang, Z Mei, Y Qi, C Yan, Q Hu, J Wang, Y Shi
Nature 471 (7338), 331-335, 2011
1582011
Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome
Q Hu, D Wu, W Chen, Z Yan, C Yan, T He, Q Liang, Y Shi
Proceedings of the National Academy of Sciences 111 (46), 16254-16261, 2014
1232014
Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme
Y Li, M Zhou, Q Hu, X Bai, W Huang, SHW Scheres, Y Shi
Proceedings of the National Academy of Sciences 114 (7), 1542-1547, 2017
1212017
GTP-State-Selective Cyclic Peptide Ligands of K-Ras (G12D) Block Its Interaction with Raf
Z Zhang, R Gao, Q Hu, H Peacock, DM Peacock, S Dai, KM Shokat, ...
ACS Central Science 6 (10), 1753–1761, 2020
832020
Proteolytic processing of the caspase-9 zymogen is required for apoptosome-mediated activation of caspase-9
Q Hu, D Wu, W Chen, Z Yan, Y Shi
Journal of Biological Chemistry 288 (21), 15142-15147, 2013
732013
Crystal structure of a bacterial homologue of SWEET transporters
J Wang, C Yan, Y Li, K Hirata, M Yamamoto, N Yan, Q Hu
Cell research 24 (12), 1486-1489, 2014
652014
Disease-Causing Mutations in the G Protein Gαs Subvert the Roles of GDP and GTP
Q Hu, KM Shokat
Cell 173 (5), 1254-1264. e11, 2018
572018
Mechanistic insights into CED-4-mediated activation of CED-3
W Huang, T Jiang, W Choi, S Qi, Y Pang, Q Hu, Y Xu, X Gong, PD Jeffrey, ...
Genes & development 27 (18), 2039-2048, 2013
452013
Development of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 3CLpro
N Hou, L Shuai, L Zhang, X Xie, K Tang, Y Zhu, Y Yu, W Zhang, Q Tan, ...
ACS central science 9 (2), 217-227, 2023
352023
State-selective modulation of heterotrimeric Gαs signaling with macrocyclic peptides
SA Dai, Q Hu, R Gao, EE Blythe, KK Touhara, H Peacock, Z Zhang, ...
Cell 185 (21), 3950-3965.e25, 2022
302022
Molecular determinants of MecA as a degradation tag for the ClpCP protease
Z Mei, F Wang, Y Qi, Z Zhou, Q Hu, H Li, J Wu, Y Shi
Journal of Biological Chemistry 284 (49), 34366-34375, 2009
302009
Chemical genetic inhibition of DEAD-box proteins using covalent complementarity
KJ Barkovich, MK Moore, Q Hu, KM Shokat
Nucleic acids research 46 (17), 8689-8699, 2018
132018
Crystal structure of the MecA degradation tag
F Wang, Z Mei, Y Qi, C Yan, S Xiang, Z Zhou, Q Hu, J Wang, Y Shi
Journal of Biological Chemistry 284 (49), 34376-34381, 2009
132009
Regulation of RAS palmitoyltransferases by accessory proteins and palmitoylation
A Yang, S Liu, Y Zhang, J Chen, Y Fan, F Wang, Y Zou, S Feng, J Wu, ...
Nature Structural & Molecular Biology, 1-11, 2024
52024
BRET-based self-cleaving biosensors for SARS-CoV-2 3CLpro inhibitor discovery
N Hou, C Peng, L Zhang, Y Zhu, Q Hu
Microbiology Spectrum 10 (4), e02559-21, 2022
42022
Novel X-linked inhibitor of apoptosis protein inhibitors as probes of apoptosis in biology and medicine
Q Hu, A Nie, K Welsh, FRP Crisóstomo, X Zhu, Z Li, J An, JC Reed, ...
Experimental Biology and Medicine 236 (2), 247-251, 2011
22011
Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04
L Zhang, X Xie, H Luo, R Qian, Y Yang, H Yu, J Huang, PY Shi, Q Hu
Cell Discovery 10 (1), 40, 2024
2024
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