Harikrishnan Parameswaran
Harikrishnan Parameswaran
Assistant Professor, Department of Bioengineering, Northeastern University
Adresse e-mail validée de northeastern.edu
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Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema
ZH Chen, HC Lam, Y Jin, HP Kim, J Cao, SJ Lee, E Ifedigbo, ...
Proceedings of the National Academy of Sciences 107 (44), 18880-18885, 2010
Alveolar macrophage activation and an emphysema-like phenotype in adiponectin-deficient mice
R Summer, FF Little, N Ouchi, Y Takemura, T Aprahamian, D Dwyer, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 294 (6 …, 2008
Mechanics, nonlinearity, and failure strength of lung tissue in a mouse model of emphysema: possible role of collagen remodeling
S Ito, EP Ingenito, KK Brewer, LD Black, H Parameswaran, KR Lutchen, ...
Journal of applied physiology 98 (2), 503-511, 2005
Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice
SM Cloonan, K Glass, ME Laucho-Contreras, AR Bhashyam, M Cervo, ...
Nature medicine 22 (2), 163-174, 2016
Tissue heterogeneity in the mouse lung: effects of elastase treatment
S Ito, EP Ingenito, SP Arold, H Parameswaran, NT Tgavalekos, ...
Journal of applied physiology 97 (1), 204-212, 2004
Quantitative characterization of airspace enlargement in emphysema
H Parameswaran, A Majumdar, S Ito, AM Alencar, B Suki
Journal of applied physiology 100 (1), 186-193, 2006
Microtubule dynamics regulate cyclic stretch-induced cell alignment in human airway smooth muscle cells
M Morioka, H Parameswaran, K Naruse, M Kondo, M Sokabe, ...
PloS one 6 (10), e26384, 2011
Three-dimensional measurement of alveolar airspace volumes in normal and emphysematous lungs using micro-CT
H Parameswaran, E Bartolák-Suki, H Hamakawa, A Majumdar, PG Allen, ...
Journal of Applied Physiology 107 (2), 583-592, 2009
Emphysema and mechanical stress-induced lung remodeling
B Suki, S Sato, H Parameswaran, MV Szabari, A Takahashi, ...
Physiology 28 (6), 404-413, 2013
Early emphysema in the tight skin and pallid mice: roles of microfibril-associated glycoproteins, collagen, and mechanical forces
S Ito, E Bartolák-Suki, JM Shipley, H Parameswaran, A Majumdar, B Suki
American journal of respiratory cell and molecular biology 34 (6), 688-694, 2006
Structure–function relations in an elastase-induced mouse model of emphysema
H Hamakawa, E Bartolák-Suki, H Parameswaran, A Majumdar, ...
American journal of respiratory cell and molecular biology 45 (3), 517-524, 2011
Fluctuation-driven mechanotransduction regulates mitochondrial-network structure and function
E Bartolák-Suki, J Imsirovic, H Parameswaran, TJ Wellman, N Martinez, ...
Nature materials 14 (10), 1049-1057, 2015
Mechanical forces regulate elastase activity and binding site availability in lung elastin
R Jesudason, S Sato, H Parameswaran, AD Araujo, A Majumdar, ...
Biophysical journal 99 (9), 3076-3083, 2010
A computational model of the response of adherent cells to stretch and changes in substrate stiffness
H Parameswaran, KR Lutchen, B Suki
Journal of applied physiology 116 (7), 825-834, 2014
Can tidal breathing with deep inspirations of intact airways create sustained bronchoprotection or bronchodilation?
BC Harvey, H Parameswaran, KR Lutchen
Journal of applied physiology 115 (4), 436-445, 2013
Proteoglycans maintain lung stability in an elastase-treated mouse model of emphysema
A Takahashi, A Majumdar, H Parameswaran, E Bartolák-Suki, B Suki
American journal of respiratory cell and molecular biology 51 (1), 26-33, 2014
Mechanical failure, stress redistribution, elastase activity and binding site availability on elastin during the progression of emphysema
B Suki, R Jesudason, S Sato, H Parameswaran, AD Araujo, A Majumdar, ...
Pulmonary pharmacology & therapeutics 25 (4), 268-275, 2012
Linking microscopic spatial patterns of tissue destruction in emphysema to macroscopic decline in stiffness using a 3D computational model
H Parameswaran, A Majumdar, B Suki
PLoS computational biology 7 (4), e1001125, 2011
Extracellular matrix stiffness regulates human airway smooth muscle contraction by altering the cell-cell coupling
SR Polio, SE Stasiak, RR Jamieson, JL Balestrini, R Krishnan, ...
Scientific reports 9 (1), 1-12, 2019
Acoustic evidence of airway opening during recruitment in excised dog lungs
Z Hantos, J Tolnai, T Asztalos, F Petak, A Adamicza, AM Alencar, ...
Journal of Applied Physiology 97 (2), 592-598, 2004
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