| Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells A Nebbioso, N Clarke, E Voltz, E Germain, C Ambrosino, P Bontempo, ... Nature medicine 11 (1), 77-84, 2005 | 612 | 2005 |
| Functions, therapeutic applications, and synthesis of retinoids and carotenoids R Alvarez, B Vaz, H Gronemeyer, AR de Lera Chemical reviews 114 (1), 1-125, 2014 | 285 | 2014 |
| Palladium‐Catalyzed Intermolecular C(sp3)H Amidation A Iglesias, R Alvarez, AR de Lera, K Muniz Angewandte Chemie International Edition 9 (51), 2225-2228, 2012 | 233 | 2012 |
| C− C reductive elimination in palladium complexes, and the role of coupling additives. A DFT study supported by experiment M Perez-Rodriguez, AAC Braga, M Garcia-Melchor, MH Perez-Temprano, ... Journal of the American Chemical Society 131 (10), 3650-3657, 2009 | 211 | 2009 |
| Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10 O Gallego, FX Ruiz, A Ardèvol, M Domínguez, R Alvarez, AR De Lera, ... Proceedings of the National Academy of Sciences 104 (52), 20764-20769, 2007 | 194 | 2007 |
| Mechanism of the gold (I)-catalyzed Rautenstrauch rearrangement: A center-to-helix-to-center chirality transfer ON Faza, CS López, R Álvarez, AR de Lera Journal of the American Chemical Society 128 (7), 2434-2437, 2006 | 167 | 2006 |
| Isomerization of all-trans-Retinol to cis-Retinols in Bovine Retinal Pigment Epithelial Cells: Dependence on the Specificity of Retinoid-Binding Proteins JK McBee, V Kuksa, R Alvarez, AR de Lera, O Prezhdo, F Haeseleer, ... Biochemistry 39 (37), 11370-11380, 2000 | 118 | 2000 |
| Palladium-catalyzed sequential oxidative cyclization/coupling of 2-alkynylphenols and alkenes: a direct entry into 3-alkenylbenzofurans C Martinez, R Alvarez, JM Aurrecoechea Organic Letters 11 (5), 1083-1086, 2009 | 117 | 2009 |
| A General Synthesis of Alkenyl‐Substituted Benzofurans, Indoles, and Isoquinolones by Cascade Palladium‐Catalyzed Heterocyclization/Oxidative Heck Coupling R Álvarez, C Martínez, Y Madich, JG Denis, JM Aurrecoechea, ... Chemistry–A European Journal 16 (42), 12746-12753, 2010 | 111 | 2010 |
| Structure, function and modulation of retinoic acid receptor beta, a tumor suppressor S Alvarez, P Germain, R Alvarez, F Rodríguez-Barrios, H Gronemeyer, ... The international journal of biochemistry & cell biology 39 (7-8), 1406-1415, 2007 | 103 | 2007 |
| On the Aromatic Character of Electrocyclic and Pseudopericyclic Reactions: Thermal Cyclization of (2Z)-Hexa-2, 4-5-trienals and Their Schiff Bases. AR de Lera, R Alvarez, B Lecea, A Torrado, FP Cossío Angewandte Chemie (International ed. in English) 40 (3), 557-561, 2001 | 100 | 2001 |
| Synthesis and biological characterization of the histone deacetylase inhibitor largazole and C7-modified analogues JA Souto, E Vaz, I Lepore, AC Pöppler, G Franci, R Alvarez, L Altucci, ... Journal of medicinal chemistry 53 (12), 4654-4667, 2010 | 96 | 2010 |
| Computational characterization of a complete palladium-catalyzed cross-coupling process: The associative transmetalation in the Stille reaction R Álvarez, ON Faza, CS López, ÁR de Lera Organic Letters 8 (1), 35-38, 2006 | 93 | 2006 |
| Macroscale plasmonic substrates for highly sensitive surface‐enhanced Raman scattering M Alba, N Pazos‐Perez, B Vaz, P Formentin, M Tebbe, MA Correa‐Duarte, ... Angewandte Chemie International Edition 52 (25), 6459-6463, 2013 | 90 | 2013 |
| Inhibition of IκB kinase-β and anticancer activities of novel chalcone adamantyl arotinoids P Lorenzo, R Alvarez, MA Ortiz, S Alvarez, FJ Piedrafita, AR de Lera Journal of medicinal chemistry 51 (17), 5431-5440, 2008 | 89 | 2008 |
| Aldo-keto reductases from the AKR1B subfamily: retinoid specificity and control of cellular retinoic acid levels FX Ruiz, O Gallego, A Ardèvol, A Moro, M Domínguez, S Alvarez, ... Chemico-biological interactions 178 (1-3), 171-177, 2009 | 85 | 2009 |
| Retinoic acid and Wnt/β-catenin have complementary roles in anterior/posterior patterning embryos of the basal chordate amphioxus T Onai, HC Lin, M Schubert, D Koop, PW Osborne, S Alvarez, R Alvarez, ... Developmental biology 332 (2), 223-233, 2009 | 84 | 2009 |
| Enantioselective synthesis of hexahydrofuro [3, 2-c] quinolines through a multicatalytic and multicomponent process. A new “aromatic sandwich” model for BINOL-phosphoric acid … J Calleja, AB González-Pérez, ÁR de Lera, R Álvarez, FJ Fañanás, ... Chemical Science 5 (3), 996-1007, 2014 | 82 | 2014 |
| Theoretical study of the electrocyclic ring closure of hydroxypentadienyl cations ON Faza, CS López, R Alvarez, AR De Lera Chemistry (Weinheim an der Bergstrasse, Germany) 10 (17), 4324-4333, 2004 | 81 | 2004 |
| New polymer-supported catalysts derived from Cinchona alkaloids: Their use in the asymmetric Michael reaction R Alvarez, MA Hourdin, C Cavé, J d'Angelo, P Chaminade Tetrahedron letters 40 (39), 7091-7094, 1999 | 78 | 1999 |
