| Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits F De Vadder, P Kovatcheva-Datchary, D Goncalves, J Vinera, C Zitoun, ... Cell 156 (1), 84-96, 2014 | 2092 | 2014 |
| Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state M Foretz, S Hébrard, J Leclerc, E Zarrinpashneh, M Soty, G Mithieux, ... The Journal of clinical investigation 120 (7), 2355-2369, 2010 | 1435 | 2010 |
| Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD A Montagner, A Polizzi, E Fouché, S Ducheix, Y Lippi, F Lasserre, ... Gut 65 (7), 1202-1214, 2016 | 603 | 2016 |
| Microbiota-produced succinate improves glucose homeostasis via intestinal gluconeogenesis F De Vadder, P Kovatcheva-Datchary, C Zitoun, A Duchampt, F Bäckhed, ... Cell metabolism 24 (1), 151-157, 2016 | 582 | 2016 |
| Short chain fatty acids in human gut and metabolic health EE Blaak, EE Canfora, S Theis, G Frost, AK Groen, G Mithieux, A Nauta, ... Beneficial microbes 11 (5), 411-455, 2020 | 576 | 2020 |
| Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing SC Cunnane, E Trushina, C Morland, A Prigione, G Casadesus, ... Nature reviews Drug discovery 19 (9), 609-633, 2020 | 525 | 2020 |
| Resveratrol protects primary rat hepatocytes against oxidative stress damage:: Activation of the Nrf2 transcription factor and augmented activities of antioxidant enzymes JA Rubiolo, G Mithieux, FV Vega European journal of pharmacology 591 (1-3), 66-72, 2008 | 417 | 2008 |
| Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice S Troy, M Soty, L Ribeiro, L Laval, S Migrenne, X Fioramonti, B Pillot, ... Cell metabolism 8 (3), 201-211, 2008 | 408 | 2008 |
| Liver adenosine monophosphate-activated kinase-α2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin F Andreelli, M Foretz, C Knauf, PD Cani, C Perrin, MA Iglesias, B Pillot, ... Endocrinology 147 (5), 2432-2441, 2006 | 299 | 2006 |
| Metabolic adaptation establishes disease tolerance to sepsis S Weis, AR Carlos, MR Moita, S Singh, B Blankenhaus, S Cardoso, ... Cell 169 (7), 1263-1275. e14, 2017 | 243 | 2017 |
| Portal sensing of intestinal gluconeogenesis is a mechanistic link in the diminution of food intake induced by diet protein G Mithieux, P Misery, C Magnan, B Pillot, A Gautier-Stein, C Bernard, ... Cell metabolism 2 (5), 321-329, 2005 | 225 | 2005 |
| Rat small intestine is an insulin-sensitive gluconeogenic organ M Croset, F Rajas, C Zitoun, JM Hurot, S Montano, G Mithieux Diabetes 50 (4), 740-746, 2001 | 225 | 2001 |
| The glucose-6 phosphatase gene is expressed in human and rat small intestine: regulation of expression in fasted and diabetic rats F Rajas, N Bruni, S Montano, C Zitoun, G Mithieux Gastroenterology 117 (1), 132-139, 1999 | 197 | 1999 |
| Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: induction of renal and intestinal gluconeogenesis by glucagon E Mutel, A Gautier-Stein, A Abdul-Wahed, M Amigó-Correig, C Zitoun, ... Diabetes 60 (12), 3121-3131, 2011 | 186 | 2011 |
| Glucose-6-phosphatase mRNA and activity are increased to the same extent in kidney and liver of diabetic rats G Mithieux, H Vidal, C Zitoun, N Bruni, N Daniele, C Minassian Diabetes 45 (7), 891-896, 1996 | 182 | 1996 |
| Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas E Mutel, A Abdul-Wahed, N Ramamonjisoa, A Stefanutti, I Houberdon, ... Journal of hepatology 54 (3), 529-537, 2011 | 159 | 2011 |
| Gut-brain glucose signaling in energy homeostasis M Soty, A Gautier-Stein, F Rajas, G Mithieux Cell metabolism 25 (6), 1231-1242, 2017 | 152 | 2017 |
| Induction of control genes in intestinal gluconeogenesis is sequential during fasting and maximal in diabetes G Mithieux, I Bady, A Gautier, M Croset, F Rajas, C Zitoun American Journal of Physiology-Endocrinology and Metabolism 286 (3), E370-E375, 2004 | 147 | 2004 |
| New knowledge regarding glucose-6 phosphatase gene and protein and their roles in the regulation of glucose metabolism G Mithieux European journal of endocrinology 136 (2), 137-145, 1997 | 147 | 1997 |
| A novel role for glucose 6-phosphatase in the small intestine in the control of glucose homeostasis G Mithieux, F Rajas, A Gautier-Stein Journal of Biological Chemistry 279 (43), 44231-44234, 2004 | 145 | 2004 |
