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Gilles Mithieux
Gilles Mithieux
Adresse e-mail validée de univ-lyon1.fr
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Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits
F De Vadder, P Kovatcheva-Datchary, D Goncalves, J Vinera, C Zitoun, ...
Cell 156 (1), 84-96, 2014
22212014
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
M Foretz, S Hébrard, J Leclerc, E Zarrinpashneh, M Soty, G Mithieux, ...
The Journal of clinical investigation 120 (7), 2355-2369, 2010
14732010
Short chain fatty acids in human gut and metabolic health
EE Blaak, EE Canfora, S Theis, G Frost, AK Groen, G Mithieux, A Nauta, ...
Beneficial microbes 11 (5), 411-455, 2020
7122020
Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD
A Montagner, A Polizzi, E Fouché, S Ducheix, Y Lippi, F Lasserre, ...
Gut 65 (7), 1202-1214, 2016
6632016
Microbiota-produced succinate improves glucose homeostasis via intestinal gluconeogenesis
F De Vadder, P Kovatcheva-Datchary, C Zitoun, A Duchampt, F Bäckhed, ...
Cell metabolism 24 (1), 151-157, 2016
6502016
Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing
SC Cunnane, E Trushina, C Morland, A Prigione, G Casadesus, ...
Nature reviews Drug discovery 19 (9), 609-633, 2020
6272020
Resveratrol protects primary rat hepatocytes against oxidative stress damage:: Activation of the Nrf2 transcription factor and augmented activities of antioxidant enzymes
JA Rubiolo, G Mithieux, FV Vega
European journal of pharmacology 591 (1-3), 66-72, 2008
4262008
Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice
S Troy, M Soty, L Ribeiro, L Laval, S Migrenne, X Fioramonti, B Pillot, ...
Cell metabolism 8 (3), 201-211, 2008
4142008
Liver adenosine monophosphate-activated kinase-α2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin
F Andreelli, M Foretz, C Knauf, PD Cani, C Perrin, MA Iglesias, B Pillot, ...
Endocrinology 147 (5), 2432-2441, 2006
3002006
Metabolic adaptation establishes disease tolerance to sepsis
S Weis, AR Carlos, MR Moita, S Singh, B Blankenhaus, S Cardoso, ...
Cell 169 (7), 1263-1275. e14, 2017
2682017
Portal sensing of intestinal gluconeogenesis is a mechanistic link in the diminution of food intake induced by diet protein
G Mithieux, P Misery, C Magnan, B Pillot, A Gautier-Stein, C Bernard, ...
Cell metabolism 2 (5), 321-329, 2005
2292005
Rat small intestine is an insulin-sensitive gluconeogenic organ
M Croset, F Rajas, C Zitoun, JM Hurot, S Montano, G Mithieux
Diabetes 50 (4), 740-746, 2001
2292001
The glucose-6 phosphatase gene is expressed in human and rat small intestine: regulation of expression in fasted and diabetic rats
F Rajas, N Bruni, S Montano, C Zitoun, G Mithieux
Gastroenterology 117 (1), 132-139, 1999
2051999
Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: induction of renal and intestinal gluconeogenesis by glucagon
E Mutel, A Gautier-Stein, A Abdul-Wahed, M Amigó-Correig, C Zitoun, ...
Diabetes 60 (12), 3121-3131, 2011
1942011
Glucose-6-phosphatase mRNA and activity are increased to the same extent in kidney and liver of diabetic rats
G Mithieux, H Vidal, C Zitoun, N Bruni, N Daniele, C Minassian
Diabetes 45 (7), 891-896, 1996
1811996
Gut microbiota, endocrine-disrupting chemicals, and the diabetes epidemic
G Velmurugan, T Ramprasath, M Gilles, K Swaminathan, S Ramasamy
Trends in Endocrinology & Metabolism 28 (8), 612-625, 2017
1652017
Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas
E Mutel, A Abdul-Wahed, N Ramamonjisoa, A Stefanutti, I Houberdon, ...
Journal of hepatology 54 (3), 529-537, 2011
1642011
Gut-brain glucose signaling in energy homeostasis
M Soty, A Gautier-Stein, F Rajas, G Mithieux
Cell metabolism 25 (6), 1231-1242, 2017
1602017
Induction of control genes in intestinal gluconeogenesis is sequential during fasting and maximal in diabetes
G Mithieux, I Bady, A Gautier, M Croset, F Rajas, C Zitoun
American Journal of Physiology-Endocrinology and Metabolism 286 (3), E370-E375, 2004
1522004
New knowledge regarding glucose-6 phosphatase gene and protein and their roles in the regulation of glucose metabolism
G Mithieux
European journal of endocrinology 136 (2), 137-145, 1997
1491997
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