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Trevor A Graham
Trevor A Graham
Director, Centre for Evolution and Cancer, ICR, London
Adresse e-mail validée de icr.ac.uk - Page d'accueil
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A Big Bang model of human colorectal tumor growth
A Sottoriva, H Kang, Z Ma, TA Graham, MP Salomon, J Zhao, P Marjoram, ...
Nature genetics 47 (3), 209-216, 2015
11612015
Pan-cancer analysis of the extent and consequences of intratumor heterogeneity
N Andor, TA Graham, M Jansen, LC Xia, CA Aktipis, C Petritsch, HP Ji, ...
Nature medicine 22 (1), 105-113, 2016
8252016
Identification of neutral tumor evolution across cancer types
MJ Williams, B Werner, CP Barnes, TA Graham, A Sottoriva
Nature genetics 48 (3), 238-244, 2016
6932016
Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential
DL Worthley, M Churchill, JT Compton, Y Tailor, M Rao, Y Si, D Levin, ...
Cell 160 (1), 269-284, 2015
6662015
Resolving genetic heterogeneity in cancer
S Turajlic, A Sottoriva, T Graham, C Swanton
Nature Reviews Genetics 20 (7), 404-416, 2019
5982019
An evolutionary perspective on field cancerization
K Curtius, NA Wright, TA Graham
Nature Reviews Cancer 18 (1), 19-32, 2018
4442018
Classifying the evolutionary and ecological features of neoplasms
CC Maley, A Aktipis, TA Graham, A Sottoriva, AM Boddy, M Janiszewska, ...
Nature Reviews Cancer 17 (10), 605-619, 2017
4132017
Forty-year analysis of colonoscopic surveillance program for neoplasia in ulcerative colitis: an updated overview
CHR Choi, MD Rutter, A Askari, GH Lee, J Warusavitarne, M Moorghen, ...
Official journal of the American College of Gastroenterology| ACG 110 (7 …, 2015
3112015
Quantification of subclonal selection in cancer from bulk sequencing data
MJ Williams, B Werner, T Heide, C Curtis, CP Barnes, A Sottoriva, ...
Nature genetics 50 (6), 895-903, 2018
2532018
Quantification of crypt and stem cell evolution in the normal and neoplastic human colon
AM Baker, B Cereser, S Melton, AG Fletcher, M Rodriguez-Justo, ...
Cell reports 8 (4), 940-947, 2014
2382014
Krt19+/Lgr5− cells are radioresistant cancer-initiating stem cells in the colon and intestine
S Asfaha, Y Hayakawa, A Muley, S Stokes, TA Graham, RE Ericksen, ...
Cell stem cell 16 (6), 627-638, 2015
2242015
Clonality, founder mutations, and field cancerization in human ulcerative colitis–associated neoplasia
SJ Leedham, TA Graham, D Oukrif, SAC McDonald, M Rodriguez–Justo, ...
Gastroenterology 136 (2), 542-550. e6, 2009
2112009
Stem cells and their implications for colorectal cancer
SS Zeki, TA Graham, NA Wright
Nature reviews Gastroenterology & hepatology 8 (2), 90-100, 2011
2002011
Detecting repeated cancer evolution from multi-region tumor sequencing data
G Caravagna, Y Giarratano, D Ramazzotti, I Tomlinson, TA Graham, ...
Nature methods 15 (9), 707-714, 2018
1792018
Between-region genetic divergence reflects the mode and tempo of tumor evolution
R Sun, Z Hu, A Sottoriva, TA Graham, A Harpak, Z Ma, JM Fischer, ...
Nature genetics 49 (7), 1015-1024, 2017
1772017
Measuring cancer evolution from the genome
TA Graham, A Sottoriva
The Journal of pathology 241 (2), 183-191, 2017
1712017
Cumulative burden of inflammation predicts colorectal neoplasia risk in ulcerative colitis: a large single-centre study
CHR Choi, I Al Bakir, NSJ Ding, GH Lee, A Askari, J Warusavitarne, ...
Gut 68 (3), 414-422, 2019
1702019
Clonality assessment and clonal ordering of individual neoplastic crypts shows polyclonality of colorectal adenomas
C Thirlwell, OCC Will, E Domingo, TA Graham, SAC McDonald, D Oukrif, ...
Gastroenterology 138 (4), 1441-1454. e7, 2010
1662010
Clonal evolution of colorectal cancer in IBD
CHR Choi, IA Bakir, AL Hart, TA Graham
Nature reviews Gastroenterology & hepatology 14 (4), 218-229, 2017
1622017
Evolutionary history of human colitis-associated colorectal cancer
AM Baker, W Cross, K Curtius, I Al Bakir, CHR Choi, HL Davis, D Temko, ...
Gut 68 (6), 985-995, 2019
1562019
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