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Wassim El Nemer
Wassim El Nemer
EFS
Adresse e-mail validée de efs.sante.fr
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Gene therapy in a patient with sickle cell disease
JA Ribeil, S Hacein-Bey-Abina, E Payen, A Magnani, M Semeraro, ...
New England Journal of Medicine 376 (9), 848-855, 2017
7482017
Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus
C Antoniani, V Meneghini, A Lattanzi, T Felix, O Romano, E Magrin, ...
Blood, The Journal of the American Society of Hematology 131 (17), 1960-1973, 2018
2102018
A biomimetic microfluidic chip to study the circulation and mechanical retention of red blood cells in the spleen
J Picot, PA Ndour, SD Lefevre, W El Nemer, H Tawfik, J Galimand, ...
American journal of hematology 90 (4), 339-345, 2015
1762015
The Lutheran blood group glycoproteins, the erythroid receptors for laminin, are adhesion molecules
W El Nemer, P Gane, Y Colin, V Bony, C Rahuel, F Galactéros, JP Cartron, ...
Journal of Biological Chemistry 273 (27), 16686-16693, 1998
1571998
Increased adhesion to endothelial cells of erythrocytes from patients with polycythemia vera is mediated by laminin α5 chain and Lu/BCAM
MP Wautier, W El Nemer, P Gane, JD Rain, JP Cartron, Y Colin, ...
Blood, The Journal of the American Society of Hematology 110 (3), 894-901, 2007
1512007
Human induced pluripotent stem cells can reach complete terminal maturation: in vivo and in vitro evidence in the erythropoietic differentiation model
L Kobari, F Yates, N Oudrhiri, A Francina, L Kiger, C Mazurier, S Rouzbeh, ...
haematologica 97 (12), 1795, 2012
1452012
Proteomic analysis of the tetraspanin web using LC‐ESI‐MS/MS and MALDI‐FTICR‐MS
M André, JP Le Caer, C Greco, S Planchon, W El Nemer, C Boucheix, ...
Proteomics 6 (5), 1437-1449, 2006
1282006
Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype
L Weber, G Frati, T Felix, G Hardouin, A Casini, C Wollenschlaeger, ...
Science advances 6 (7), eaay9392, 2020
1182020
JAK2V617F activates Lu/BCAM-mediated red cell adhesion in polycythemia vera through an EpoR-independent Rap1/Akt pathway
M De Grandis, M Cambot, MP Wautier, B Cassinat, C Chomienne, Y Colin, ...
Blood, The Journal of the American Society of Hematology 121 (4), 658-665, 2013
1062013
The European hematology association roadmap for European hematology research: a consensus document
A Engert, C Balduini, A Brand, B Coiffier, C Cordonnier, H Döhner, ...
haematologica 101 (2), 115, 2016
932016
Absolute proteome quantification of highly purified populations of circulating reticulocytes and mature erythrocytes
EF Gautier, M Leduc, S Cochet, K Bailly, C Lacombe, N Mohandas, ...
Blood advances 2 (20), 2646-2657, 2018
812018
Protein kinase A-dependent phosphorylation of Lutheran/basal cell adhesion molecule glycoprotein regulates cell adhesion to laminin α5
E Gauthier, C Rahuel, MP Wautier, W El Nemer, P Gane, JL Wautier, ...
Journal of Biological Chemistry 280 (34), 30055-30062, 2005
812005
Decreased sickle red blood cell adhesion to laminin by hydroxyurea is associated with inhibition of Lu/BCAM protein phosphorylation
P Bartolucci, V Chaar, J Picot, D Bachir, A Habibi, C Fauroux, ...
Blood, The Journal of the American Society of Hematology 116 (12), 2152-2159, 2010
802010
Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: the HGB-205 trial
E Magrin, M Semeraro, N Hebert, L Joseph, A Magnani, A Chalumeau, ...
Nature Medicine 28 (1), 81-88, 2022
742022
Endothelial cells harbouring the JAK2V617F mutation display pro-adherent and pro-thrombotic features
A Guadall, E Lesteven, G Letort, SA Toor, M Delord, D Pognant, ...
Thrombosis and haemostasis 118 (09), 1586-1599, 2018
732018
Organization of the Human LU Gene and Molecular Basis of the Lua/Lub Blood Group Polymorphism
W El Nemer, C Rahuel, Y Colin, P Gane, JP Cartron, C Le Van Kim
Blood, The Journal of the American Society of Hematology 89 (12), 4608-4616, 1997
711997
Endothelial Lu/BCAM glycoproteins are novel ligands for red blood cell α4β1integrin: role in adhesion of sickle red blood cells to endothelial cells
W El Nemer, MP Wautier, C Rahuel, P Gane, P Hermand, F Galactéros, ...
Blood 109 (8), 3544-3551, 2007
672007
Resolution of sickle cell disease–associated inflammation and tissue damage with 17R-resolvin D1
A Matte, A Recchiuti, E Federti, B Koehl, T Mintz, W El Nemer, PL Tharaux, ...
Blood, The Journal of the American Society of Hematology 133 (3), 252-265, 2019
612019
Isoforms of the Lutheran/basal cell adhesion molecule glycoprotein are differentially delivered in polarized epithelial cells: mapping of the basolateral sorting signal to a …
W El Nemer, Y Colin, C Bauvy, P Codogno, RH Fraser, JP Cartron, ...
Journal of Biological Chemistry 274 (45), 31903-31908, 1999
581999
Aggregation of mononuclear and red blood cells through an α4β1-Lu/basal cell adhesion molecule interaction in sickle cell disease
V Chaar, J Picot, O Renaud, P Bartolucci, R Nzouakou, D Bachir, ...
haematologica 95 (11), 1841, 2010
472010
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