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Pinaki Datta
Pinaki Datta
Scientist, Teva Pharmaceutical Industries, Ltd
Verified email at tevapharm.com
Title
Cited by
Cited by
Year
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
T Fernandes-Alnemri, JW Yu, P Datta, J Wu, ES Alnemri
Nature 458 (7237), 509-513, 2009
20422009
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
SM Srinivasula, R Hegde, A Saleh, P Datta, E Shiozaki, J Chai, RA Lee, ...
Nature 410 (6824), 112-116, 2001
13902001
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
T Fernandes-Alnemri, J Wu, JW Yu, P Datta, B Miller, W Jankowski, ...
Cell Death & Differentiation 14 (9), 1590-1604, 2007
11632007
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
T Fernandes-Alnemri, JW Yu, C Juliana, L Solorzano, S Kang, J Wu, ...
Nature immunology 11 (5), 385-393, 2010
8352010
The PYRIN-CARD protein ASC is an activating adaptor for caspase-1
SM Srinivasula, JL Poyet, M Razmara, P Datta, ZJ Zhang, ES Alnemri
Journal of Biological Chemistry 277 (24), 21119-21122, 2002
7122002
Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome
C Juliana, T Fernandes-Alnemri, J Wu, P Datta, L Solorzano, JW Yu, ...
Journal of Biological Chemistry 285 (13), 9792-9802, 2010
6042010
Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway
SM Srinivasula, P Datta, XJ Fan, T Fernandes-Alnemri, Z Huang, ...
Journal of Biological Chemistry 275 (46), 36152-36157, 2000
4812000
Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice
JM Jones, P Datta, SM Srinivasula, W Ji, S Gupta, ZJ Zhang, E Davies, ...
Nature 425 (6959), 721-727, 2003
4622003
Cryopyrin and pyrin activate caspase-1, but not NF-κ B, via ASC oligomerization
JW Yu, J Wu, Z Zhang, P Datta, I Ibrahimi, S Taniguchi, J Sagara, ...
Cell Death & Differentiation 13 (2), 236-249, 2006
4482006
Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants
JW Yu, T Fernandes-Alnemri, P Datta, J Wu, C Juliana, L Solorzano, ...
Molecular cell 28 (2), 214-227, 2007
3272007
Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2
SM Srinivasula, S Gupta, P Datta, ZJ Zhang, R Hegde, NE Cheong, ...
Journal of biological chemistry 278 (34), 31469-31472, 2003
2712003
The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity
S Park, C Juliana, S Hong, P Datta, I Hwang, T Fernandes-Alnemri, JW Yu, ...
The Journal of Immunology 191 (8), 4358-4366, 2013
2682013
sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein
SM Srinivasula, P Datta, M Kobayashi, JW Wu, M Fujioka, R Hegde, ...
Current biology 12 (2), 125-130, 2002
1722002
The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein
R Hegde, SM Srinivasula, P Datta, M Madesh, R Wassell, ZJ Zhang, ...
Journal of Biological Chemistry 278 (40), 38699-38706, 2003
1222003
The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity
S Gupta, R Singh, P Datta, ZJ Zhang, C Orr, Z Lu, G DuBois, AS Zervos, ...
Journal of Biological Chemistry 279 (44), 45844-45854, 2004
1102004
Small terminase couples viral DNA binding to genome-packaging ATPase activity
A Roy, A Bhardwaj, P Datta, GC Lander, G Cingolani
Structure 20 (8), 1403-1413, 2012
812012
Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging
S Kang, JP Louboutin, P Datta, CP Landel, D Martinez, AS Zervos, ...
Cell Death & Differentiation 20 (2), 259-269, 2013
762013
The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila
FS Khan, M Fujioka, P Datta, T Fernandes-Alnemri, JB Jaynes, ...
Cell Death & Differentiation 15 (6), 1073-1083, 2008
332008
Translation termination factor eRF3 is targeted for caspase-mediated proteolytic cleavage and degradation during DNA damage-induced apoptosis
Y Hashimoto, N Hosoda, P Datta, ES Alnemri, S Hoshino
Apoptosis 17 (12), 1287-1299, 2012
172012
correction: a conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
SM Srinivasula, R Hegde, A Saleh, P Datta, E Shiozaki, J Chai, RA Lee, ...
Nature 411 (6841), 1081-1081, 2001
102001
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