| Synthesis and evaluation of nitroheterocyclic phosphoramidates as hypoxia-selective alkylating agents RF Borch, J Liu, JP Schmidt, JT Marakovits, C Joswig, JJ Gipp, ... Journal of medicinal chemistry 43 (11), 2258-2265, 2000 | 78 | 2000 |
| Small molecule quantification by liquid chromatography-mass spectrometry for metabolites of drugs and drug candidates UP Dahal, JP Jones, JA Davis, DA Rock Drug metabolism and disposition 39 (12), 2355-2360, 2011 | 67 | 2011 |
| Nitrobenzyl phosphorodiamidates as potential hypoxia-selective alkylating agents RT Mulcahy, JJ Gipp, JP Schmidt, C Joswig, RF Borch Journal of medicinal chemistry 37 (11), 1610-1615, 1994 | 65 | 1994 |
| Synthesis and biological evaluation of 5-fluoro-2'-deoxyuridine phosphoramidate analogs KM Fries, C Joswig, RF Borch Journal of medicinal chemistry 38 (14), 2672-2680, 1995 | 59 | 1995 |
| Synthesis and biological activity of novel 5-fluoro-2 ‘-deoxyuridine phosphoramidate prodrugs CL Freel Meyers, L Hong, C Joswig, RF Borch Journal of medicinal chemistry 43 (22), 4313-4318, 2000 | 58 | 2000 |
| Purification and mechanism of human aldehyde oxidase expressed in Escherichia coli JF Alfaro, CA Joswig-Jones, W Ouyang, J Nichols, GJ Crouch, JP Jones Drug metabolism and disposition 37 (12), 2393-2398, 2009 | 57 | 2009 |
| Antitumor activity and toxicity of novel nitroheterocyclic phosphoramidates RF Borch, J Liu, C Joswig, RB Baggs, DL Dexter, GL Mangold Journal of medicinal chemistry 44 (1), 74-77, 2001 | 40 | 2001 |
| Comparative study of the affinity and metabolism of type I and type II binding quinoline carboxamide analogues by cytochrome P450 3A4 UP Dahal, C Joswig-Jones, JP Jones Journal of medicinal chemistry 55 (1), 280-290, 2012 | 36 | 2012 |
| In vitro oxidative metabolism of 6-mercaptopurine in human liver: insights into the role of the molybdoflavoenzymes aldehyde oxidase, xanthine oxidase, and xanthine dehydrogenase KV Choughule, C Barnaba, CA Joswig-Jones, JP Jones Drug Metabolism and Disposition 42 (8), 1334-1340, 2014 | 35 | 2014 |
| Absolute quantification of aldehyde oxidase protein in human liver using liquid chromatography–tandem mass spectrometry JT Barr, JP Jones, CA Joswig-Jones, DA Rock Molecular pharmaceutics 10 (10), 3842-3849, 2013 | 35 | 2013 |
| Interspecies differences in the metabolism of methotrexate: an insight into the active site differences between human and rabbit aldehyde oxidase KV Choughule, CA Joswig-Jones, JP Jones Biochemical pharmacology 96 (3), 288-295, 2015 | 34 | 2015 |
| The effects of type II binding on metabolic stability and binding affinity in cytochrome P450 CYP3A4 CC Peng, JT Pearson, DA Rock, CA Joswig-Jones, JP Jones Archives of biochemistry and biophysics 497 (1-2), 68-81, 2010 | 34 | 2010 |
| Time course of aldehyde oxidase and why it is nonlinear A Abbasi, EM Paragas, CA Joswig-Jones, JT Rodgers, JP Jones Drug Metabolism and Disposition 47 (5), 473-483, 2019 | 31 | 2019 |
| The kinetic mechanism for cytochrome P450 metabolism of type II binding compounds: evidence supporting direct reduction J Pearson, UP Dahal, D Rock, CC Peng, JO Schenk, C Joswig-Jones, ... Archives of biochemistry and biophysics 511 (1-2), 69-79, 2011 | 30 | 2011 |
| Why do most human liver cytosol preparations lack xanthine oxidase activity? JT Barr, KV Choughule, S Nepal, T Wong, AS Chaudhry, ... Drug metabolism and disposition 42 (4), 695-699, 2014 | 28 | 2014 |
| The two faces of aldehyde oxidase: oxidative and reductive transformations of 5-nitroquinoline EM Paragas, SC Humphreys, J Min, CA Joswig-Jones, JP Jones Biochemical Pharmacology 145, 210-217, 2017 | 27 | 2017 |
| The effects of nitrogen-heme-iron coordination on substrate affinities for cytochrome P450 2E1 JP Jones, CA Joswig-Jones, M Hebner, Y Chu, DR Koop Chemico-biological interactions 193 (1), 50-56, 2011 | 26 | 2011 |
| ecoAO: a simple system for the study of human aldehyde oxidases role in drug metabolism EM Paragas, SC Humphreys, J Min, CA Joswig-Jones, S Leimkühler, ... ACS omega 2 (8), 4820-4827, 2017 | 11 | 2017 |
| Site-directed mutagenesis at the molybdenum pterin cofactor site of the human aldehyde oxidase: Interrogating the kinetic differences between human and cynomolgus monkey A Abbasi, CA Joswig-Jones, JP Jones Drug Metabolism and Disposition 48 (12), 1364-1371, 2020 | 5 | 2020 |
| Site Directed Mutagenesis at the MoCo Site of the Human Aldehyde Oxidase: Interrogating the Kinetic Differences Between Human and Cynomolgus Monkey A Abbasi, CA Joswig-Jones, JP Jones Drug Metabolism and Disposition, 2020 | 2 | 2020 |
