Genetic basis for clinical response to CTLA-4 blockade in melanoma A Snyder, V Makarov, T Merghoub, J Yuan, JM Zaretsky, A Desrichard, ... New England Journal of Medicine 371 (23), 2189-2199, 2014 | 4454 | 2014 |
Tumor and microenvironment evolution during immunotherapy with nivolumab N Riaz, JJ Havel, V Makarov, A Desrichard, WJ Urba, JS Sims, FS Hodi, ... Cell 171 (4), 934-949. e16, 2017 | 1715 | 2017 |
Inhibiting DNA methylation causes an interferon response in cancer via dsRNA including endogenous retroviruses KB Chiappinelli, PL Strissel, A Desrichard, H Li, C Henke, B Akman, ... Cell 162 (5), 974-986, 2015 | 1713 | 2015 |
The head and neck cancer immune landscape and its immunotherapeutic implications R Mandal, Y Şenbabaoğlu, A Desrichard, JJ Havel, MG Dalin, N Riaz, ... JCI insight 1 (17), 2016 | 680 | 2016 |
Pan-cancer analysis of intratumor heterogeneity as a prognostic determinant of survival LGT Morris, N Riaz, A Desrichard, Y Şenbabaoğlu, AA Hakimi, V Makarov, ... Oncotarget 7 (9), 10051, 2016 | 291 | 2016 |
Cancer neoantigens and applications for immunotherapy A Desrichard, A Snyder, TA Chan Clinical Cancer Research 22 (4), 807-812, 2016 | 276 | 2016 |
NF-κB c-Rel is crucial for the regulatory T cell immune checkpoint in cancer Y Grinberg-Bleyer, H Oh, A Desrichard, DM Bhatt, R Caron, TA Chan, ... Cell 170 (6), 1096-1108. e13, 2017 | 269 | 2017 |
Comprehensive molecular characterization of salivary duct carcinoma reveals actionable targets and similarity to apocrine breast cancer MG Dalin, A Desrichard, N Katabi, V Makarov, LA Walsh, KW Lee, ... Clinical cancer research 22 (18), 4623-4633, 2016 | 173 | 2016 |
The role of neoantigens in response to immune checkpoint blockade N Riaz, L Morris, JJ Havel, V Makarov, A Desrichard, TA Chan International immunology 28 (8), 411-419, 2016 | 162 | 2016 |
Tobacco smoking-associated alterations in the immune microenvironment of squamous cell carcinomas A Desrichard, F Kuo, D Chowell, KW Lee, N Riaz, RJ Wong, TA Chan, ... JNCI: Journal of the National Cancer Institute 110 (12), 1386-1392, 2018 | 140 | 2018 |
Recurrent SERPINB3 and SERPINB4 mutations in patients who respond to anti-CTLA4 immunotherapy N Riaz, JJ Havel, SM Kendall, V Makarov, LA Walsh, A Desrichard, ... Nature genetics 48 (11), 1327-1329, 2016 | 135 | 2016 |
Multicentric neoadjuvant phase II study of panitumumab combined with an anthracycline/taxane-based chemotherapy in operable triple-negative breast cancer: identification of … JM Nabholtz, C Abrial, MA Mouret-Reynier, MM Dauplat, B Weber, ... Annals of oncology 25 (8), 1570-1577, 2014 | 121 | 2014 |
CHEK2 contribution to hereditary breast cancer in non-BRCAfamilies A Desrichard, Y Bidet, N Uhrhammer, YJ Bignon Breast Cancer Research 13, 1-11, 2011 | 113 | 2011 |
An integrated systems biology approach identifies TRIM25 as a key determinant of breast cancer metastasis LA Walsh, MJ Alvarez, EY Sabio, M Reyngold, V Makarov, S Mukherjee, ... Cell reports 20 (7), 1623-1640, 2017 | 99 | 2017 |
Multi-dimensional genomic analysis of myoepithelial carcinoma identifies prevalent oncogenic gene fusions MG Dalin, N Katabi, M Persson, KW Lee, V Makarov, A Desrichard, ... Nature communications 8 (1), 1197, 2017 | 89 | 2017 |
Bi‐allelic alterations in DNA repair genes underpin homologous recombination DNA repair defects in breast cancer RW Mutter, N Riaz, CKY Ng, R Delsite, S Piscuoglio, M Edelweiss, ... The Journal of pathology 242 (2), 165-177, 2017 | 54 | 2017 |
Integrated genomics for pinpointing survival loci within arm-level somatic copy number alterations DM Roy, LA Walsh, A Desrichard, JT Huse, W Wu, JJ Gao, P Bose, W Lee, ... Cancer cell 29 (5), 737-750, 2016 | 54 | 2016 |
Diet-induced hypoxia responsive element demethylation increases CEACAM6 expression, favouring Crohn's disease-associated Escherichia coli colonisation J Denizot, A Desrichard, A Agus, N Uhrhammer, N Dreux, ... Gut 64 (3), 428-437, 2015 | 45 | 2015 |
Positive link between variant Toll-like receptor 4 (Asp299Gly and Thr399Ile) and colorectal cancer patients with advanced stage and lymph node metastasis I Omrane, O Baroudi, N Kourda, YJ Bignon, N Uhrhammer, A Desrichard, ... Tumor Biology 35, 545-551, 2014 | 45 | 2014 |
CD97 is a critical regulator of acute myeloid leukemia stem cell function GH Martin, N Roy, S Chakraborty, A Desrichard, SS Chung, CM Woolthuis, ... Journal of Experimental Medicine 216 (10), 2362-2377, 2019 | 40 | 2019 |