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David McGivern
David McGivern
Verified email at fda.hhs.gov
Title
Cited by
Cited by
Year
Competing and noncompeting activities of miR-122 and the 5′ exonuclease Xrn1 in regulation of hepatitis C virus replication
Y Li, T Masaki, D Yamane, DR McGivern, SM Lemon
Proceedings of the National Academy of Sciences 110 (5), 1881-1886, 2013
2812013
Virus-specific mechanisms of carcinogenesis in hepatitis C virus associated liver cancer
DR McGivern, SM Lemon
Oncogene 30 (17), 1969-1983, 2011
2382011
Hepatitis C virus induces E6AP-dependent degradation of the retinoblastoma protein
T Munakata, Y Liang, S Kim, DR McGivern, J Huibregtse, A Nomoto, ...
PLoS pathogens 3 (9), e139, 2007
1712007
Unravelling the complexities of respiratory syncytial virus RNA synthesis
VM Cowton, DR McGivern, R Fearns
Journal of general virology 87 (7), 1805-1821, 2006
1552006
Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation
D Yamane, DR McGivern, E Wauthier, MK Yi, VJ Madden, C Welsch, ...
Nature medicine 20 (8), 927-935, 2014
1492014
Protease inhibitor–resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus
T Shimakami, C Welsch, D Yamane, DR McGivern, MK Yi, S Zeuzem, ...
Gastroenterology 140 (2), 667-675, 2011
1482011
miR-122 stimulates hepatitis C virus RNA synthesis by altering the balance of viral RNAs engaged in replication versus translation
T Masaki, KC Arend, Y Li, D Yamane, DR McGivern, T Kato, T Wakita, ...
Cell host & microbe 17 (2), 217-228, 2015
1432015
Is hepatitis C virus carcinogenic?
SM Lemon, DR McGivern
Gastroenterology 142 (6), 1274-1278, 2012
1322012
Kinetic analyses reveal potent and early blockade of hepatitis C virus assembly by NS5A inhibitors
DR McGivern, T Masaki, S Williford, P Ingravallo, Z Feng, F Lahser, ...
Gastroenterology 147 (2), 453-462. e7, 2014
1282014
Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein
AGN Angus, D Dalrymple, S Boulant, DR McGivern, RF Clayton, MJ Scott, ...
Journal of general virology 91 (1), 122-132, 2010
1122010
Tumor suppressors, chromosomal instability, and hepatitis C virus–associated liver cancer
DR McGivern, SM Lemon
Annual Review of Pathology: Mechanisms of Disease 4, 399-415, 2009
1102009
Hepatitis C virus infection causes cell cycle arrest at the level of initiation of mitosis
RP Kannan, LL Hensley, LE Evers, SM Lemon, DR McGivern
Journal of virology 85 (16), 7989-8001, 2011
1092011
MAVS-dependent host species range and pathogenicity of human hepatitis A virus
A Hirai-Yuki, L Hensley, DR McGivern, O González-López, A Das, H Feng, ...
Science 353 (6307), 1541-1545, 2016
892016
Liver injury and disease pathogenesis in chronic hepatitis C
D Yamane, DR McGivern, T Masaki, SM Lemon
Hepatitis C virus: from molecular virology to antiviral therapy, 263-288, 2013
892013
Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells
H Dansako, D Yamane, C Welsch, DR McGivern, F Hu, N Kato, ...
PLoS pathogens 9 (5), e1003345, 2013
822013
NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR
H Feng, EM Lenarcic, D Yamane, E Wauthier, J Mo, H Guo, DR McGivern, ...
Nature immunology 18 (12), 1299-1309, 2017
772017
Roles of the respiratory syncytial virus trailer region: effects of mutations on genome production and stress granule formation
LL Hanley, DR McGivern, MN Teng, R Djang, PL Collins, R Fearns
Virology 406 (2), 241-252, 2010
732010
Identification of internal sequences in the 3′ leader region of human respiratory syncytial virus that enhance transcription and confer replication processivity
DR McGivern, PL Collins, R Fearns
Journal of virology 79 (4), 2449-2460, 2005
702005
How do persistent infections with hepatitis C virus cause liver cancer?
JK Mitchell, SM Lemon, DR McGivern
Current opinion in virology 14, 101-108, 2015
642015
Chronic hepatitis C infection–induced liver fibrogenesis is associated with M2 macrophage activation
MT Bility, K Nio, F Li, DR McGivern, SM Lemon, ER Feeney, RT Chung, ...
Scientific reports 6 (1), 39520, 2016
622016
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