| H2S-Induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response N Krishnan, C Fu, DJ Pappin, NK Tonks Science signaling 4 (203), ra86-ra86, 2011 | 471 | 2011 |
| Proline modulates the intracellular redox environment and protects mammalian cells against oxidative stress N Krishnan, MB Dickman, DF Becker Free Radical Biology and Medicine 44 (4), 671-681, 2008 | 380 | 2008 |
| Targeting the disordered C terminus of PTP1B with an allosteric inhibitor N Krishnan, D Koveal, DH Miller, B Xue, SD Akshinthala, J Kragelj, ... Nature chemical biology 10 (7), 558-566, 2014 | 355 | 2014 |
| Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A. X is mediated by the protein phosphatase eyes absent N Krishnan, DG Jeong, SK Jung, SE Ryu, A Xiao, CD Allis, SJ Kim, ... Journal of Biological Chemistry 284 (24), 16066-16070, 2009 | 162 | 2009 |
| Effect of Farnesol on a Mouse Model of Systemic Candidiasis, Determined by Use of a DPP3 Knockout Mutant of Candida albicans DH Navarathna, JM Hornby, N Krishnan, A Parkhurst, GE Duhamel, ... Infection and immunity 75 (4), 1609-1618, 2007 | 157 | 2007 |
| A potent, selective, and orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models N Krishnan, KF Konidaris, G Gasser, NK Tonks Journal of Biological Chemistry 293 (5), 1517-1525, 2018 | 113 | 2018 |
| Structure and kinetics of monofunctional proline dehydrogenase from Thermus thermophilus TA White, N Krishnan, DF Becker, JJ Tanner Journal of Biological Chemistry 282 (19), 14316-14327, 2007 | 113 | 2007 |
| Reactivation of oxidized PTP1B and PTEN by thioredoxin 1 U Schwertassek, A Haque, N Krishnan, R Greiner, L Weingarten, TP Dick, ... The FEBS journal 281 (16), 3545-3558, 2014 | 105 | 2014 |
| PTP1B inhibition suggests a therapeutic strategy for Rett syndrome N Krishnan, K Krishnan, CR Connors, MS Choy, R Page, W Peti, ... The Journal of clinical investigation 125 (8), 3163-3177, 2015 | 96 | 2015 |
| Crystal structure of the bifunctional proline utilization A flavoenzyme from Bradyrhizobium japonicum D Srivastava, JP Schuermann, TA White, N Krishnan, N Sanyal, GL Hura, ... Proceedings of the National Academy of Sciences 107 (7), 2878-2883, 2010 | 73 | 2010 |
| The anti‐inflammatory compound BAY‐11‐7082 is a potent inhibitor of protein tyrosine phosphatases N Krishnan, G Bencze, P Cohen, NK Tonks The FEBS journal 280 (12), 2830-2841, 2013 | 69 | 2013 |
| Oxygen Reactivity of PutA from Helicobacter Species and Proline-Linked Oxidative Stress N Krishnan, DF Becker Journal of bacteriology 188 (4), 1227-1235, 2006 | 60 | 2006 |
| Harnessing insulin-and leptin-induced oxidation of PTP1B for therapeutic development N Krishnan, CA Bonham, IA Rus, OK Shrestha, CM Gauss, A Haque, ... Nature communications 9 (1), 283, 2018 | 52 | 2018 |
| Characterization of a Helicobacter hepaticus putA Mutant Strain in Host Colonization and Oxidative Stress N Krishnan, AR Doster, GE Duhamel, DF Becker Infection and immunity 76 (7), 3037-3044, 2008 | 44 | 2008 |
| Characterization of a Bifunctional PutA Homologue from Bradyrhizobium japonicum and Identification of an Active Site Residue that Modulates Proline Reduction of … N Krishnan, DF Becker Biochemistry 44 (25), 9130-9139, 2005 | 43 | 2005 |
| DPM-1001 decreased copper levels and ameliorated deficits in a mouse model of Wilson's disease N Krishnan, C Felice, K Rivera, DJ Pappin, NK Tonks Genes & Development 32 (13-14), 944-952, 2018 | 36 | 2018 |
| Evidence for hysteretic substrate channeling in the proline dehydrogenase and Δ1-pyrroline-5-carboxylate dehydrogenase coupled reaction of proline utilization A (PutA) MA Moxley, N Sanyal, N Krishnan, JJ Tanner, DF Becker Journal of Biological Chemistry 289 (6), 3639-3651, 2014 | 31 | 2014 |
| The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity CK Baumgartner, H Ebrahimi-Nik, A Iracheta-Vellve, KM Hamel, ... Nature 622 (7984), 850-862, 2023 | 26 | 2023 |
| Kinetic and thermodynamic analysis of Bradyrhizobium japonicum PutA–membrane associations W Zhang, N Krishnan, DF Becker Archives of biochemistry and biophysics 445 (1), 174-183, 2006 | 15 | 2006 |
| A novel phosphatidic acid-protein-tyrosine phosphatase D2 axis is essential for ERBB2 signaling in mammary epithelial cells M Ramesh, N Krishnan, SK Muthuswamy, NK Tonks Journal of Biological Chemistry 290 (15), 9646-9659, 2015 | 12 | 2015 |
