Suivre
Kelvin Yen
Kelvin Yen
Research Associate Professor, The University of Southern California
Adresse e-mail validée de usc.edu
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Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants
A Bansal, LJ Zhu, K Yen, HA Tissenbaum
Proceedings of the National Academy of Sciences 112 (3), E277-E286, 2015
3612015
Humanin: a harbinger of mitochondrial-derived peptides?
C Lee, K Yen, P Cohen
Trends in Endocrinology & Metabolism 24 (5), 222-228, 2013
2922013
A comparative study of fat storage quantitation in nematode Caenorhabditis elegans using label and label-free methods
K Yen, TT Le, A Bansal, SD Narasimhan, JX Cheng, HA Tissenbaum
PloS one 5 (9), e12810, 2010
2812010
Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers
LJ Cobb, C Lee, J Xiao, K Yen, RG Wong, HK Nakamura, HH Mehta, ...
Aging (Albany NY) 8 (4), 796, 2016
2352016
A new DAF-16 isoform regulates longevity
ES Kwon, SD Narasimhan, K Yen, HA Tissenbaum
Nature 466 (7305), 498-502, 2010
2242010
The emerging role of the mitochondrial-derived peptide humanin in stress resistance
K Yen, C Lee, H Mehta, P Cohen
J Mol Endocrinol 50 (1), R11-R19, 2013
2182013
Converging pathways in lifespan regulation
SD Narasimhan, K Yen, HA Tissenbaum
Current Biology 19 (15), R657-R666, 2009
1942009
Mitochondrially derived peptides as novel regulators of metabolism
SJ Kim, J Xiao, J Wan, P Cohen, K Yen
The Journal of physiology 595 (21), 6613-6621, 2017
1702017
The mitochondrial-derived peptide humanin protects RPE cells from oxidative stress, senescence, and mitochondrial dysfunction
PG Sreekumar, K Ishikawa, C Spee, HH Mehta, J Wan, K Yen, P Cohen, ...
Investigative ophthalmology & visual science 57 (3), 1238-1253, 2016
1672016
Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling
M Zhang, M Poplawski, K Yen, H Cheng, E Bloss, X Zhu, H Patel, ...
PLoS biology 7 (11), e1000245, 2009
1362009
FDA-approved drugs that protect mammalian neurons from glucose toxicity slow aging dependent on cbp and protect against proteotoxicity
A Lublin, F Isoda, H Patel, K Yen, L Nguyen, D Hajje, M Schwartz, ...
PloS one 6 (11), e27762, 2011
982011
The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus
SJ Kim, N Guerrero, G Wassef, J Xiao, HH Mehta, P Cohen, K Yen
Oncotarget 7 (30), 46899, 2016
932016
PDP-1 links the TGF-β and IIS pathways to regulate longevity, development, and metabolism
SD Narasimhan, K Yen, A Bansal, ES Kwon, S Padmanabhan, ...
PLoS genetics 7 (4), e1001377, 2011
912011
Hypothalamic-pituitary axis regulates hydrogen sulfide production
C Hine, HJ Kim, Y Zhu, E Harputlugil, A Longchamp, MS Matos, ...
Cell metabolism 25 (6), 1320-1333. e5, 2017
872017
Effects of air pollution on mitochondrial function, mitochondrial DNA methylation, and mitochondrial peptide expression
CV Breton, AY Song, J Xiao, SJ Kim, HH Mehta, J Wan, K Yen, C Sioutas, ...
Mitochondrion 46, 22-29, 2019
852019
DAF-16/Forkhead box O transcription factor: many paths to a single Fork (head) in the road
K Yen, SD Narasimhan, HA Tissenbaum
Antioxidants & redox signaling 14 (4), 623-634, 2011
842011
IGF‐I regulates the age‐dependent signaling peptide humanin
C Lee, J Wan, B Miyazaki, Y Fang, J Guevara‐Aguirre, K Yen, V Longo, ...
Aging Cell 13 (5), 958-961, 2014
832014
Impaired glucose signaling as a cause of obesity and the metabolic syndrome: the glucoadipostatic hypothesis
CV Mobbs, F Isoda, H Makimura, J Mastaitis, T Mizuno, IW Shu, K Yen, ...
Physiology & behavior 85 (1), 3-23, 2005
832005
The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan
K Yen, HH Mehta, SJ Kim, YH Lue, J Hoang, N Guerrero, J Port, Q Bi, ...
Aging (Albany NY) 12 (12), 11185, 2020
812020
Humanin prevents age-related cognitive decline in mice and is associated with improved cognitive age in humans
K Yen, J Wan, HH Mehta, B Miller, A Christensen, ME Levine, ...
Scientific reports 8 (1), 14212, 2018
812018
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