Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo S Philippe, C Sarkis, M Barkats, H Mammeri, C Ladroue, C Petit, J Mallet, ... Proceedings of the National Academy of Sciences 103 (47), 17684-17689, 2006 | 314 | 2006 |
The HIV-1 DNA flap stimulates HIV vector-mediated cell transduction in the brain V Zennou, C Serguera, C Sarkis, P Colin, E Perret, J Mallet, P Charneau Nature biotechnology 19 (5), 446-450, 2001 | 262 | 2001 |
Efficient transduction of neural cells in vitro and in vivo by a baculovirus-derived vector C Sarkis, C Serguera, S Petres, D Buchet, JL Ridet, L Edelman, J Mallet Proceedings of the National Academy of Sciences 97 (26), 14638-14643, 2000 | 249 | 2000 |
Non-integrating lentiviral vectors C Sarkis, S Philippe, J Mallet, C Serguera Current gene therapy 8 (6), 430-437, 2008 | 94 | 2008 |
Control of erythropoietin secretion by doxycycline or mifepristone in mice bearing polymer-encapsulated engineered cells C Serguera, D Bohl, E Rolland, P Prevost, JM Heard Human gene therapy 10 (3), 375-383, 1999 | 82 | 1999 |
Cell death and neuronal differentiation of glioblastoma stem‐like cells induced by neurogenic transcription factors PO Guichet, I Bieche, M Teigell, C Serguera, B Rothhut, V Rigau, ... Glia 61 (2), 225-239, 2013 | 71 | 2013 |
Induction of experimental autoimmune encephalomyelitis with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund’s adjuvant in three non-human primate species KG Haanstra, SA Jagessar, AL Bauchet, M Doussau, CM Fovet, ... Journal of Neuroimmune Pharmacology 8, 1251-1264, 2013 | 65 | 2013 |
Increased dopamine after mating impairs olfaction and prevents odor interference with pregnancy C Serguera, V Triaca, J Kelly-Barrett, MA Banchaabouchi, L Minichiello Nature neuroscience 11 (8), 949-956, 2008 | 65 | 2008 |
Cranial nerve involvement in patients with MOG antibody–associated disease A Cobo-Calvo, X Ayrignac, P Kerschen, P Horellou, F Cotton, P Labauge, ... Neurology: Neuroimmunology & Neuroinflammation 6 (2), e543, 2019 | 62 | 2019 |
Long-term expression of β-glucuronidase by genetically modified human neural progenitor cells grafted into the mouse central nervous system D Buchet, C Serguera, V Zennou, P Charneau, J Mallet Molecular and Cellular Neuroscience 19 (3), 389-401, 2002 | 62 | 2002 |
Grafted human embryonic progenitors expressing neurogenin-2 stimulate axonal sprouting and improve motor recovery after severe spinal cord injury FE Perrin, G Boniface, C Serguera, N Lonjon, A Serre, M Prieto, J Mallet, ... PLoS One 5 (12), e15914, 2010 | 48 | 2010 |
Increased interleukin-6 correlates with myelin oligodendrocyte glycoprotein antibodies in pediatric monophasic demyelinating diseases and multiple sclerosis P Horellou, M Wang, V Keo, P Chrétien, C Serguera, P Waters, K Deiva Journal of neuroimmunology 289, 1-7, 2015 | 43 | 2015 |
Transplantation of human adult astrocytes: efficiency and safety requirements for an autologous gene therapy JL Ridet, C Sarkis, C Serguera, V Zennou, P Charneau, J Mallet Journal of neuroscience research 72 (6), 704-708, 2003 | 29 | 2003 |
Primary adult human astrocytes as an ex vivo vehicle for β-glucuronidase delivery in the brain C Serguera, C Sarkis, JL Ridet, P Colin, P Moullier, J Mallet Molecular Therapy 3 (6), 875-881, 2001 | 25 | 2001 |
Experimental models of autoimmune demyelinating diseases in nonhuman primates L Stimmer, CM Fovet, C Serguera Veterinary pathology 55 (1), 27-41, 2018 | 23 | 2018 |
Integration of genetically modified adult astrocytes into the lesioned rat spinal cord P Pencalet, C Serguera, O Corti, A Privat, J Mallet, M Giménez y Ribotta Journal of neuroscience research 83 (1), 61-67, 2006 | 21 | 2006 |
Gene therapy of the central nervous system: general considerations on viral vectors for gene transfer into the brain C Serguera, AP Bemelmans Revue neurologique 170 (12), 727-738, 2014 | 20 | 2014 |
Comparison between several integrase-defective lentiviral vectors reveals increased integration of an HIV vector bearing a D167H mutant MQ Saeed, N Dufour, C Bartholmae, U Sieranska, M Knopf, E Thierry, ... Molecular Therapy-Nucleic Acids 3, 2014 | 20 | 2014 |
Non-integrative and non-replicative lentivirus, preparation and uses thereof J Mallet, C Serguera, S Philippe, C Sarkis US Patent 8,119,119, 2012 | 20 | 2012 |
Influence of insulators on transgene expression from integrating and non-integrating lentiviral vectors N Grandchamp, D Henriot, S Philippe, L Amar, S Ursulet, C Serguera, ... Genetic vaccines and therapy 9, 1-8, 2011 | 18 | 2011 |