Discovery of 4-Aminobutyric Acid Derivatives Possessing Anticonvulsant and Antinociceptive Activities: A Hybrid Pharmacophore Approach JS Perumal Yogeeswari, Jegadeesan Vaigunda Ragavendran, Dharmarajan Sriram ... Journal of Medicinal Chemistry 50 (10), 2459-2467, 2007 | 37 | 2007 |
Azido-iodo-N-benzyl derivatives of threo-methylphenidate (Ritalin, Concerta): Rational design, synthesis, pharmacological evaluation, and dopamine transporter photoaffinity … DJ Lapinsky, R Velagaleti, N Yarravarapu, Y Liu, Y Huang, CK Surratt, ... Bioorganic & medicinal chemistry 19 (1), 504-512, 2011 | 26 | 2011 |
Development of a triazole class of highly potent Porcn inhibitors L You, C Zhang, N Yarravarapu, L Morlock, X Wang, L Zhang, ... Bioorganic & medicinal chemistry letters 26 (24), 5891-5895, 2016 | 23 | 2016 |
Regulation of tankyrase activity by a catalytic domain dimer interface C Fan, N Yarravarapu, H Chen, O Kulak, P Dasari, J Herbert, ... Biochemical and biophysical research communications 503 (3), 1780-1785, 2018 | 20 | 2018 |
Integration of CRISPR/Cas9 with artificial intelligence for improved cancer therapeutics AA Bhat, S Nisar, S Mukherjee, N Saha, N Yarravarapu, SN Lone, ... Journal of translational medicine 20 (1), 534, 2022 | 19 | 2022 |
Stereoselective fatty acylation is essential for the release of lipidated WNT proteins from the acyltransferase Porcupine (PORCN) R Tuladhar, N Yarravarapu, Y Ma, C Zhang, J Herbert, J Kim, C Chen, ... Journal of Biological Chemistry 294 (16), 6273-6282, 2019 | 16 | 2019 |
SNi′ displacements with main group organometallics RKV Devambatla, R Velagaleti, N Yarravarapu, FF Fleming Tetrahedron 68 (14), 2925-2942, 2012 | 15 | 2012 |
Exo-enzymatic addition of diazirine-modified sialic acid to cell surfaces enables photocrosslinking of glycoproteins N Yarravarapu, RSR Konada, N Darabedian, NJ Pedowtiz, ... Bioconjugate Chem, 2022 | 11 | 2022 |
Evolution of a Compact Photoprobe for the Dopamine Transporter Based on (±)-threo-Methylphenidate DJ Lapinsky, N Yarravarapu, TL Nolan, CK Surratt, JR Lever, ... ACS medicinal chemistry letters 3 (5), 378-382, 2012 | 10 | 2012 |
Clickable photoaffinity ligands for the human serotonin transporter based on the selective serotonin reuptake inhibitor (S)-citalopram N Yarravarapu, L Geffert, CK Surratt, M Cascio, DJ Lapinsky Bioorganic & medicinal chemistry letters 28 (21), 3431-3435, 2018 | 8 | 2018 |
Novel Azido-Iodo Photoaffinity Ligands for the Human Serotonin Transporter Based on the Selective Serotonin Reuptake Inhibitor (S)-Citalopram V Kumar, N Yarravarapu, DJ Lapinsky, D Perley, B Felts, MJ Tomlinson, ... Journal of medicinal chemistry 58 (14), 5609-5619, 2015 | 8 | 2015 |
4-Deoxy-4-fluoro-GalNAz (4FGalNAz) Is a Metabolic Chemical Reporter of O-GlcNAc Modifications, Highlighting the Notable Substrate Flexibility of O-GlcNAc Transferase MRP Emma G. Jackson, Giuliano Cutolo, Bo Yang, Nageswari Yarravarapu, Mary W ... ACS Chemical Biology, 2021 | 7 | 2021 |
Efficient Approaches for the Synthesis of Diverse α-Diazo Amides S Chow, AI Green, C Arter, S Liver, A Leggott, L Trask, G Karageorgis, ... Synthesis 52 (11), 1695-1706, 2020 | 7 | 2020 |
A synthetic combinatorial approach to disabling deviant Hedgehog signaling CCLL C-W. Fan, N. Yarravarapu, H. Shi, O. Kulak, J. Kim Scientific Reports, 2018 | 6 | 2018 |
Disubstituted and trisubstituted 1, 2, 3-triazoles as Wnt inhibitors N Yarravarapu, C Chen, L Lum, YOU Lin, C Zhang, X Wang, L Zhang US Patent 10,793,544, 2020 | 1 | 2020 |
Exo-enzymatic mapping of glycan mediated interactions on cell surfaces using diazirine-modified sugars RSR Konada, N Yarravarapu, N Darabedian, NJ Pedowitz, ... GLYCOBIOLOGY 32 (11), 1050-1050, 2022 | | 2022 |
DISUBSTITUTED AND TRISUBSTITUTED 1,2,3-TRIAZOLES AS WNT INHIBITORS XWLZ Nageswari YARRAVARAPU, Chuo CHEN, Lawrence LUM, Lin YOU, Chengwei ZHANG US Patent PCT/US2017/049,634, 2018 | | 2018 |
Monitoring Wnt Protein Acylation Using an In Vitro Cyclo-Addition Reaction. LL Tuladhar R, Yarravarapu N Methods in molecular biology 1481, 11-16, 2016 | | 2016 |
Monoamine Transporter Photoaffinity Ligands Based On Methylphenidate and Citalopram: Rational Design, Chemical Synthesis, and Biochemical Application N Yarravarapu | | 2015 |
Binding ensemble profiling with (f) photoaffinity labeling (BEProFL): Mapping the binding sites and poses of selective serotonin reuptake inhibitors (SSRIs) within the … N Yarravarapu, DJ Lapinsky, T Nolan, CK Surrat, M Cascio ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 244, 2012 | | 2012 |