| IAP antagonists target cIAP1 to induce TNFα-dependent apoptosis JE Vince, WWL Wong, N Khan, R Feltham, D Chau, AU Ahmed, ... Cell 131 (4), 682-693, 2007 | 1256 | 2007 |
| Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction TL Haas, CH Emmerich, B Gerlach, AC Schmukle, SM Cordier, E Rieser, ... Molecular cell 36 (5), 831-844, 2009 | 853 | 2009 |
| Pyroptosis versus necroptosis: similarities, differences, and crosstalk D Frank, JE Vince Cell Death & Differentiation 26 (1), 99-114, 2019 | 784 | 2019 |
| RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL KE Lawlor, N Khan, A Mildenhall, M Gerlic, BA Croker, AA D’Cruz, C Hall, ... Nature communications 6 (1), 6282, 2015 | 594 | 2015 |
| RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis JA Rickard, JA O’Donnell, JM Evans, N Lalaoui, AR Poh, TW Rogers, ... Cell 157 (5), 1175-1188, 2014 | 587 | 2014 |
| Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation JE Vince, WWL Wong, I Gentle, KE Lawlor, R Allam, L O'Reilly, K Mason, ... Immunity 36 (2), 215-227, 2012 | 521 | 2012 |
| AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC V Sagulenko, SJ Thygesen, DP Sester, A Idris, JA Cridland, PR Vajjhala, ... Cell Death & Differentiation 20 (9), 1149-1160, 2013 | 490 | 2013 |
| The NLRP3 inflammasome in health and disease: the good, the bad and the ugly P Menu, JE Vince Clinical & Experimental Immunology 166 (1), 1-15, 2011 | 428 | 2011 |
| Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G Núñez, ... Proceedings of the National Academy of Sciences 114 (6), E961-E969, 2017 | 386 | 2017 |
| TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα JE Vince, D Chau, B Callus, WWL Wong, CJ Hawkins, P Schneider, ... The Journal of cell biology 182 (1), 171-184, 2008 | 271 | 2008 |
| TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (TNF) to efficiently activate NF-κB and to prevent TNF-induced apoptosis JE Vince, D Pantaki, R Feltham, PD Mace, SM Cordier, AC Schmukle, ... Journal of Biological Chemistry 284 (51), 35906-35915, 2009 | 264 | 2009 |
| Mitochondrial apoptosis is dispensable for NLRP 3 inflammasome activation but non‐apoptotic caspase‐8 is required for inflammasome priming R Allam, KE Lawlor, ECW Yu, AL Mildenhall, DM Moujalled, RS Lewis, ... EMBO reports 15 (9), 982-990, 2014 | 240 | 2014 |
| The pathogen Candida albicans hijacks pyroptosis for escape from macrophages N Uwamahoro, J Verma-Gaur, HH Shen, Y Qu, R Lewis, J Lu, K Bambery, ... MBio 5 (2), 10.1128/mbio. 00003-14, 2014 | 193 | 2014 |
| Surface determinants of Leishmania parasites and their role in infectivity in the mammalian host T Naderer, JE Vince, MJ McConville Current molecular medicine 4 (6), 649-665, 2004 | 190 | 2004 |
| The mitochondrial apoptotic effectors BAX/BAK activate caspase-3 and-7 to trigger NLRP3 inflammasome and caspase-8 driven IL-1β activation JE Vince, D De Nardo, W Gao, AJ Vince, C Hall, K McArthur, D Simpson, ... Cell reports 25 (9), 2339-2353. e4, 2018 | 185 | 2018 |
| Oxidative stress and NLRP3-inflammasome activity as significant drivers of diabetic cardiovascular complications: therapeutic implications A Sharma, M Tate, G Mathew, JE Vince, RH Ritchie, JB De Haan Frontiers in physiology 9, 331431, 2018 | 183 | 2018 |
| EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation JS Pearson, C Giogha, S Mühlen, U Nachbur, CLL Pham, Y Zhang, ... Nature microbiology 2 (4), 1-10, 2017 | 175 | 2017 |
| Birinapant, a smac-mimetic with improved tolerability for the treatment of solid tumors and hematological malignancies SM Condon, Y Mitsuuchi, Y Deng, MG LaPorte, SR Rippin, T Haimowitz, ... Journal of medicinal chemistry 57 (9), 3666-3677, 2014 | 174 | 2014 |
| TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1 DM Moujalled, WD Cook, T Okamoto, J Murphy, KE Lawlor, JE Vince, ... Cell death & disease 4 (1), e465-e465, 2013 | 174 | 2013 |
| The intersection of cell death and inflammasome activation JE Vince, J Silke Cellular and Molecular Life Sciences 73, 2349-2367, 2016 | 172 | 2016 |
Kate E LawlorGroup Head, Cell Death and Inflammatory Signalling, Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research and Adjunct Research Fellow, Department of Molecular and Translational Science, Monash UniversityAdresse e-mail validée de hudson.org.au
