| ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A SJ Hatsell, V Idone, DMA Wolken, L Huang, HJ Kim, L Wang, X Wen, ... Science translational medicine 7 (303), 303ra137-303ra137, 2015 | 398 | 2015 |
| Small-molecule antagonists for CXCR2 and CXCR1 inhibit human melanoma growth by decreasing tumor cell proliferation, survival, and angiogenesis S Singh, A Sadanandam, KC Nannuru, ML Varney, R Mayer-Ezell, ... Clinical Cancer Research 15 (7), 2380-2386, 2009 | 178 | 2009 |
| CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion S Singh, KC Nannuru, A Sadanandam, ML Varney, RK Singh British journal of cancer 100 (10), 1638-1646, 2009 | 144 | 2009 |
| Matrix metalloproteinase (MMP)-13 regulates mammary tumor–induced osteolysis by activating MMP9 and transforming growth factor-β signaling at the tumor-bone interface KC Nannuru, M Futakuchi, ML Varney, TM Vincent, EG Marcusson, ... Cancer research 70 (9), 3494-3504, 2010 | 141 | 2010 |
| Targeting CXCR2 enhances chemotherapeutic response, inhibits mammary tumor growth, angiogenesis, and lung metastasis B Sharma, DM Nawandar, KC Nannuru, ML Varney, RK Singh Molecular cancer therapeutics 12 (5), 799-808, 2013 | 137 | 2013 |
| Cathepsin G Enhances Mammary Tumor–Induced Osteolysis by Generating Soluble Receptor Activator of Nuclear Factor-κb Ligand TJ Wilson, KC Nannuru, M Futakuchi, A Sadanandam, RK Singh Cancer research 68 (14), 5803-5811, 2008 | 104 | 2008 |
| Cathepsin G-mediated enhanced TGF-β signaling promotes angiogenesis via upregulation of VEGF and MCP-1 TJ Wilson, KC Nannuru, M Futakuchi, RK Singh Cancer letters 288 (2), 162-169, 2010 | 97 | 2010 |
| Role of chemokine receptor CXCR2 expression in mammary tumor growth, angiogenesis and metastasis KC Nannuru, B Sharma, ML Varney, RK Singh Journal of carcinogenesis 10, 2011 | 75 | 2011 |
| Cathepsin G–mediated activation of pro–matrix metalloproteinase 9 at the tumor-bone Interface promotes transforming growth factor-β signaling and bone destruction TJ Wilson, KC Nannuru, RK Singh Molecular Cancer Research 7 (8), 1224-1233, 2009 | 74 | 2009 |
| Small interfering RNA‐mediated CXCR1 or CXCR2 knock‐down inhibits melanoma tumor growth and invasion S Singh, A Sadanandam, ML Varney, KC Nannuru, RK Singh International journal of cancer 126 (2), 328-336, 2010 | 67 | 2010 |
| Transforming growth factor‐β signaling at the tumor–bone interface promotes mammary tumor growth and osteoclast activation M Futakuchi, KC Nannuru, ML Varney, A Sadanandam, K Nakao, K Asai, ... Cancer science 100 (1), 71-81, 2009 | 67 | 2009 |
| The expansion of heterotopic bone in fibrodysplasia ossificans progressiva is activin A‐dependent J Upadhyay, LQ Xie, L Huang, N Das, RC Stewart, MC Lyon, K Palmer, ... Journal of Bone and Mineral Research 32 (12), 2489-2499, 2017 | 56 | 2017 |
| Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop S Aykul, RA Corpina, EJ Goebel, CJ Cunanan, A Dimitriou, HJ Kim, ... Elife 9, e54582, 2020 | 55 | 2020 |
| Cathepsin G recruits osteoclast precursors via proteolytic activation of protease-activated receptor-1 TJ Wilson, KC Nannuru, RK Singh Cancer Research 69 (7), 3188-3195, 2009 | 51 | 2009 |
| Tumor-stromal interactions in bone metastasis KC Nannuru, RK Singh Current osteoporosis reports 8, 105-113, 2010 | 50 | 2010 |
| Host Cxcr2-dependent regulation of mammary tumor growth and metastasis B Sharma, KC Nannuru, ML Varney, RK Singh Clinical & experimental metastasis 32, 65-72, 2015 | 42 | 2015 |
| In Vivo Quantitative Microcomputed Tomographic Analysis of Vasculature and Organs in a Normal and Diseased Mouse Model NM Das, S Hatsell, K Nannuru, L Huang, X Wen, L Wang, LH Wang, ... PLoS One 11 (2), e0150085, 2016 | 38 | 2016 |
| Activin A does not drive post-traumatic heterotopic ossification C Hwang, CA Pagani, N Das, S Marini, AK Huber, LQ Xie, J Jimenez, ... Bone 138, 115473, 2020 | 27 | 2020 |
| Functional biology of the Steel syndrome founder allele and evidence for clan genomics derivation of COL27A1 pathogenic alleles worldwide C Gonzaga-Jauregui, G Yesil, H Nistala, A Gezdirici, Y Bayram, ... European Journal of Human Genetics 28 (9), 1243-1264, 2020 | 27 | 2020 |
| Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1 S Aykul, L Huang, L Wang, NM Das, S Reisman, Y Ray, Q Zhang, ... The Journal of Clinical Investigation 132 (12), 2022 | 24 | 2022 |
