| TREM2 variants in Alzheimer's disease R Guerreiro, A Wojtas, J Bras, M Carrasquillo, E Rogaeva, E Majounie, ... New England Journal of Medicine 368 (2), 117-127, 2013 | 3061 | 2013 |
| Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease C Cruchaga, CM Karch, SC Jin, BA Benitez, Y Cai, R Guerreiro, O Harari, ... Nature 505 (7484), 550-554, 2014 | 523 | 2014 |
| GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer’s disease C Cruchaga, JSK Kauwe, O Harari, SC Jin, Y Cai, CM Karch, BA Benitez, ... Neuron 78 (2), 256-268, 2013 | 378 | 2013 |
| Coding variants in TREM2 increase risk for Alzheimer's disease SC Jin, BA Benitez, CM Karch, B Cooper, T Skorupa, D Carrell, JB Norton, ... Human molecular genetics 23 (21), 5838-5846, 2014 | 294 | 2014 |
| TREM2 variant p. R47H as a risk factor for sporadic amyotrophic lateral sclerosis J Cady, ED Koval, BA Benitez, C Zaidman, J Jockel-Balsarotti, P Allred, ... JAMA neurology 71 (4), 449-453, 2014 | 277 | 2014 |
| TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis F Cignarella, F Filipello, B Bollman, C Cantoni, A Locca, R Mikesell, ... Acta neuropathologica 140, 513-534, 2020 | 225 | 2020 |
| The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk Y Deming, F Filipello, F Cignarella, C Cantoni, S Hsu, R Mikesell, Z Li, ... Science translational medicine 11 (505), eaau2291, 2019 | 208 | 2019 |
| Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy S Da Mesquita, Z Papadopoulos, T Dykstra, L Brase, FG Farias, M Wall, ... Nature 593 (7858), 255-260, 2021 | 204 | 2021 |
| TREM2 is associated with the risk of Alzheimer's disease in Spanish population BA Benitez, B Cooper, P Pastor, SC Jin, E Lorenzo, S Cervantes, ... Neurobiology of aging 34 (6), 1711. e15-1711. e17, 2013 | 173 | 2013 |
| A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain JL Del-Aguila, Z Li, U Dube, KA Mihindukulasuriya, JP Budde, ... Alzheimer's research & therapy 11, 1-16, 2019 | 154 | 2019 |
| TREM2 is associated with increased risk for Alzheimer’s disease in African Americans SC Jin, MM Carrasquillo, BA Benitez, T Skorupa, D Carrell, D Patel, ... Molecular neurodegeneration 10, 1-7, 2015 | 147 | 2015 |
| Missense variant in TREML2 protects against Alzheimer's disease BA Benitez, SC Jin, R Guerreiro, R Graham, J Lord, D Harold, R Sims, ... Neurobiology of aging 35 (6), 1510. e19-1510. e26, 2014 | 143 | 2014 |
| Exome-sequencing confirms DNAJC5 mutations as cause of adult neuronal ceroid-lipofuscinosis BA Benitez, D Alvarado, Y Cai, K Mayo, S Chakraverty, J Norton, ... PloS one 6 (11), e26741, 2011 | 133 | 2011 |
| Variants in GBA, SNCA, and MAPT influence Parkinson disease risk, age at onset, and progression AA Davis, KM Andruska, BA Benitez, BA Racette, JS Perlmutter, ... Neurobiology of aging 37, 209. e1-209. e7, 2016 | 131 | 2016 |
| C9orf72 hexanucleotide repeat expansions in clinical Alzheimer disease M Harms, BA Benitez, N Cairns, B Cooper, P Cooper, K Mayo, D Carrell, ... JAMA neurology 70 (6), 736-741, 2013 | 128 | 2013 |
| APOE genotype regulates pathology and disease progression in synucleinopathy AA Davis, CE Inman, ZM Wargel, U Dube, BM Freeberg, A Galluppi, ... Science translational medicine 12 (529), eaay3069, 2020 | 125 | 2020 |
| Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders C Yang, FHG Farias, L Ibanez, A Suhy, B Sadler, MV Fernandez, F Wang, ... Nature neuroscience 24 (9), 1302-1312, 2021 | 120 | 2021 |
| Regulation of ceramide-induced neuronal death: cell metabolism meets neurodegeneration G Arboleda, LC Morales, B Ben tez, H Arboleda Brain research reviews 59 (2), 333-346, 2009 | 120 | 2009 |
| Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer's disease Ibero-American … SC Jin, P Pastor, B Cooper, S Cervantes, BA Benitez, C Razquin, A Goate, ... Alzheimer's research & therapy 4, 1-9, 2012 | 116 | 2012 |
| TREM2 and neurodegenerative disease. BA Benitez, C Cruchaga The New England journal of medicine 369 (16), 1567-1568, 2013 | 99 | 2013 |
Carlos CruchagaProfessor. NeuroGenomics and Informatics Center DirectorAdresse e-mail validée de wustl.edu
