Ken Solt
Ken Solt
Associate Professor of Anaesthesia, Harvard Medical School
Adresse e-mail validée de mgh.harvard.edu - Page d'accueil
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The ageing brain: age-dependent changes in the electroencephalogram during propofol and sevoflurane general anaesthesia
PL Purdon, KJ Pavone, O Akeju, AC Smith, AL Sampson, J Lee, DW Zhou, ...
British journal of anaesthesia 115 (suppl_1), i46-i57, 2015
1902015
Reversal of general anesthesia by administration of methylphenidate, amphetamine, modafinil, amantadine, and/or caffeine
EN Brown, PL Purdon
US Patent 10,299,720, 2019
1522019
Methylphenidate actively induces emergence from general anesthesia
K Solt, JF Cotten, A Cimenser, KFK Wong, JJ Chemali, EN Brown
The Journal of the American Society of Anesthesiologists 115 (4), 791-803, 2011
1452011
Correlating the clinical actions and molecular mechanisms of general anesthetics
K Solt, SA Forman
Current Opinion in Anesthesiology 20 (4), 300-306, 2007
1262007
Optogenetic activation of dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia
NE Taylor, CJ Van Dort, JD Kenny, JZ Pei, JA Guidera, KY Vlasov, JT Lee, ...
Proceedings of the National Academy of Sciences 113 (45), 12826-12831, 2016
1182016
Active emergence from propofol general anesthesia is induced by methylphenidate
JJ Chemali, CJ Van Dort, EN Brown, K Solt
The Journal of the American Society of Anesthesiologists 116 (5), 998-1005, 2012
952012
Differential modulation of human N-methyl-D-aspartate receptors by structurally diverse general anesthetics
K Solt, EI Eger, DE Raines
Anesthesia & Analgesia 102 (5), 1407-1411, 2006
942006
Electrical stimulation of the ventral tegmental area induces reanimation from general anesthesia
K Solt, CJ Van Dort, JJ Chemali, NE Taylor, JD Kenny, EN Brown
Anesthesiology 121 (2), 311-319, 2014
932014
Activation of D1 dopamine receptors induces emergence from isoflurane general anesthesia
NE Taylor, JJ Chemali, EN Brown, K Solt
The Journal of the American Society of Anesthesiologists 118 (1), 30-39, 2013
792013
Towards a comprehensive understanding of anesthetic mechanisms of action: a decade of discovery
HC Hemmings Jr, PM Riegelhaupt, MB Kelz, K Solt, RG Eckenhoff, ...
Trends in pharmacological sciences 40 (7), 464-481, 2019
552019
Case 40-2012: a 43-year-old woman with cardiorespiratory arrest after a cesarean section
JL Ecker, K Solt, MG Fitzsimons, TE MacGillivray
New England Journal of Medicine 367 (26), 2528-2536, 2012
552012
Case 40-2012: a 43-year-old woman with cardiorespiratory arrest after a cesarean section
JL Ecker, K Solt, MG Fitzsimons, TE MacGillivray
New England Journal of Medicine 367 (26), 2528-2536, 2012
552012
Modulation of human 5-hydroxytryptamine type 3AB receptors by volatile anesthetics and n-alcohols
R Stevens, D Rüsch, K Solt, DE Raines, PA Davies
Journal of Pharmacology and Experimental Therapeutics 314 (1), 338-345, 2005
502005
Synthesis of trifluoromethylaryl diazirine and benzophenone derivatives of etomidate that are potent general anesthetics and effective photolabels for probing sites on ligand …
SS Husain, S Nirthanan, D Ruesch, K Solt, Q Cheng, GD Li, E Arevalo, ...
Journal of medicinal chemistry 49 (16), 4818-4825, 2006
492006
Burst suppression probability algorithms: state-space methods for tracking EEG burst suppression
J Chemali, SN Ching, PL Purdon, K Solt, EN Brown
Journal of neural engineering 10 (5), 056017, 2013
452013
Real-time closed-loop control in a rodent model of medically induced coma using burst suppression
SN Ching, MY Liberman, JJ Chemali, MB Westover, JD Kenny, K Solt, ...
Anesthesiology 119 (4), 848-860, 2013
442013
Differential effects of serotonin and dopamine on human 5-HT3A receptor kinetics: interpretation within an allosteric kinetic model
K Solt, D Ruesch, SA Forman, PA Davies, DE Raines
Journal of Neuroscience 27 (48), 13151-13160, 2007
432007
Contrasting roles of the N-methyl-D-aspartate receptor in the production of immobilization by conventional and aromatic anesthetics
EI Eger, M Liao, MJ Laster, A Won, J Popovich, DE Raines, K Solt, ...
Anesthesia & Analgesia 102 (5), 1397-1406, 2006
422006
A brain-machine interface for control of medically-induced coma
MM Shanechi, JJ Chemali, M Liberman, K Solt, EN Brown
PLoS Comput Biol 9 (10), e1003284, 2013
412013
General anesthetic-induced channel gating enhancement of 5-hydroxytryptamine type 3 receptors depends on receptor subunit composition
K Solt, RJ Stevens, PA Davies, DE Raines
Journal of Pharmacology and Experimental Therapeutics 315 (2), 771-776, 2005
402005
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