Patrick M Collins
Patrick M Collins
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Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
KA Stannard, PM Collins, K Ito, EM Sullivan, SA Scott, E Gabutero, ...
Cancer letters 299 (2), 95-110, 2010
A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density
NM Pearce, T Krojer, AR Bradley, P Collins, RP Nowak, R Talon, ...
Nature communications 8, 15123, 2017
Slow diffusion of lactose out of galectin-3 crystals monitored by X-ray crystallography: possible implications for ligand-exchange protocols
PM Collins, KIPJ Hidari, H Blanchard
Acta Crystallographica Section D: Biological Crystallography 63 (3), 415-419, 2007
Galectin-3 interactions with glycosphingolipids
PM Collins, K Bum-Erdene, X Yu, H Blanchard
Journal of molecular biology 426 (7), 1439-1451, 2014
Galectin‐3‐binding glycomimetics that strongly reduce bleomycin‐induced lung fibrosis and modulate intracellular glycan recognition
T Delaine, P Collins, A MacKinnon, G Sharma, J Stegmayr, VK Rajput, ...
ChemBioChem 17 (18), 1759-1770, 2016
Galectin-3 inhibitors: a patent review (2008–present)
H Blanchard, X Yu, PM Collins, K Bum-Erdene
Expert opinion on therapeutic patents 24 (10), 1053-1065, 2014
A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP (2), an atypical bromodomain
OB Cox, T Krojer, P Collins, O Monteiro, R Talon, A Bradley, O Fedorov, ...
Chemical science 7 (3), 2322-2330, 2016
Taloside Inhibitors of Galectin‐1 and Galectin‐3
PM Collins, CT Öberg, H Leffler, UJ Nilsson, H Blanchard
Chemical biology & drug design 79 (3), 339-346, 2012
Investigation into the feasibility of thioditaloside as a novel scaffold for galectin‐3‐specific inhibitors
K Bum‐Erdene, IA Gagarinov, PM Collins, M Winger, AG Pearson, ...
ChemBioChem 14 (11), 1331-1342, 2013
Towards understanding the functional role of the glycosyltransferases involved in the biosynthesis of Moraxella catarrhalis lipooligosaccharide
IR Peak, ID Grice, I Faglin, Z Klipic, PM Collins, L van Schendel, ...
The FEBS journal 274 (8), 2024-2037, 2007
Gentle, fast and effective crystal soaking by acoustic dispensing
PM Collins, JT Ng, R Talon, K Nekrosiute, T Krojer, A Douangamath, ...
Acta Crystallographica Section D: Structural Biology 73 (3), 246-255, 2017
A Selective Galactose–Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model
VK Rajput, A MacKinnon, S Mandal, P Collins, H Blanchard, H Leffler, ...
Journal of medicinal chemistry 59 (17), 8141-8147, 2016
The XChemExplorer graphical workflow tool for routine or large-scale protein–ligand structure determination
T Krojer, R Talon, N Pearce, P Collins, A Douangamath, J Brandao-Neto, ...
Acta Crystallographica Section D: Structural Biology 73 (3), 267-278, 2017
Identification of a novel glycosyltransferase involved in LOS biosynthesis of Moraxella catarrhalis
JC Wilson, PM Collins, Z Klipic, ID Grice, IR Peak
Carbohydrate research 341 (15), 2600-2606, 2006
Synthesis and Demonstration of the Biological Relevance of sp3‐rich Scaffolds Distantly Related to Natural Product Frameworks
DJ Foley, PGE Craven, PM Collins, RG Doveston, A Aimon, R Talon, ...
Chemistry–A European Journal 23 (60), 15227-15232, 2017
Characterization of three druggable hot-spots in the aurora-A/TPX2 interaction using biochemical, biophysical, and fragment-based approaches
PJ McIntyre, PM Collins, L Vrzal, K Birchall, LH Arnold, C Mpamhanga, ...
ACS chemical biology 12 (11), 2906-2914, 2017
Small molecule antagonists of the interaction between the histone deacetylase 6 zinc-finger domain and ubiquitin
RJ Harding, R Ferreira de Freitas, P Collins, I Franzoni, M Ravichandran, ...
Journal of medicinal chemistry 60 (21), 9090-9096, 2017
Identification of a capsular polysaccharide from Moraxella bovis
JC Wilson, PG Hitchen, M Frank, IR Peak, PM Collins, HR Morris, A Dell, ...
Carbohydrate research 340 (4), 765-769, 2005
An Unusual Carbohydrate Conformation is Evident in Moraxella catarrhalis Oligosaccharides
M Frank, P Collins, I Peak, I Grice, J Wilson
molecules 20 (8), 14234-14253, 2015
Biochemical analysis of Lgt3, a glycosyltransferase of the bacterium Moraxella catarrhalis
I Faglin, J Tiralongo, JC Wilson, PM Collins, IR Peak
Biochemical and biophysical research communications 393 (4), 609-613, 2010
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