| Inert and seed-competent tau monomers suggest structural origins of aggregation H Mirbaha, D Chen, OA Morazova, KM Ruff, AM Sharma, X Liu, ... Elife 7, e36584, 2018 | 239 | 2018 |
| Tau local structure shields an amyloid-forming motif and controls aggregation propensity D Chen, KW Drombosky, Z Hou, L Sari, OM Kashmer, BD Ryder, ... Nature communications 10 (1), 2493, 2019 | 132 | 2019 |
| Seed-competent tau monomer initiates pathology in a tauopathy mouse model H Mirbaha, D Chen, V Mullapudi, SJ Terpack, CL White, LA Joachimiak, ... Journal of Biological Chemistry 298 (8), 2022 | 21 | 2022 |
| Biophysical properties of a tau seed Z Hou, D Chen, BD Ryder, LA Joachimiak Scientific reports 11 (1), 13602, 2021 | 21 | 2021 |
| FTD-tau S320F mutation stabilizes local structure and allosterically promotes amyloid motif-dependent aggregation D Chen, S Bali, R Singh, A Wosztyl, V Mullapudi, J Vaquer-Alicea, ... Nature communications 14 (1), 1625, 2023 | 7 | 2023 |
| Spontaneous motor-behavior abnormalities in two Drosophila models of neurodevelopmental disorders DR Andrew, ME Moe, D Chen, JA Tello, RL Doser, WE Conner, ... Journal of Neurogenetics 35 (1), 1-22, 2021 | 4 | 2021 |
| Tau local structure shields an amyloid-forming motif and controls aggregation propensity. Nat Commun 10: 2493 D Chen, KW Drombosky, Z Hou, L Sari, OM Kashmer, BD Ryder, ... | 4 | 2019 |
| Native tau structure is disrupted by disease-associated mutations that promote aggregation KW Drombosky, D Chen, D Woodard, L Sari, M Lin, MI Diamond, ... bioRxiv, 330266, 2018 | 3 | 2018 |
| Saturation mutagenesis of α-synuclein reveals monomer fold that modulates aggregation J Chlebowicz, W Russ, D Chen, A Vega, S Vernino, CL White III, J Rizo, ... Science Advances 9 (43), eadh3457, 2023 | 2 | 2023 |
| Seed-competent tau monomer initiates pathology in PS19 tauopathy mice H Mirbaha, D Chen, V Mullapudi, SJ Terpack, CL White 3rd, ... bioRxiv, 2022.01. 03.474806, 2022 | 2 | 2022 |
| Cross-linking mass spectrometry analysis of metastable compact structures in intrinsically disordered proteins D Chen, LA Joachimiak Protein Aggregation: Methods and Protocols, 189-201, 2022 | 1 | 2022 |
| Ensemble-based design of tau to inhibit aggregation while preserving biological activity L Joachimiak, S Bali, R Singh, P Wydorski, A Wosztyl, V Perez, D Chen, ... | | 2024 |
| Ensemble-based design of tau to inhibit aggregation while preserving biological activity. S Bali, R Singh, PM Wydorski, A Wosztyl, VA Perez, D Chen, J Rizo, ... bioRxiv, 2023.12. 13.571598, 2023 | | 2023 |
| Tau peptide antigens and antibodies binding thereto for the treatment of tauopathies MI Diamond, K Drombosky, C Dailu, V Manon, X Liu, H Mirzaei, ... US Patent App. 17/295,152, 2022 | | 2022 |
| Mechanistic Investigation into the Regulation of Amyloid Motifs in Tau Aggregation and Disease D Chen | | 2022 |
| Tau local structure shields amyloid motif and controls aggregation propensity D Chen, KW Drombosky, Z Hou, L Sari, OM Kashmer, BD Ryder, ... bioRxiv, 330266, 2019 | | 2019 |
