| Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk KD Mayer-Barber, BB Andrade, SD Oland, EP Amaral, DL Barber, ... Nature 511 (7507), 99-103, 2014 | 809 | 2014 |
| A major role for ferroptosis in Mycobacterium tuberculosis–induced cell death and tissue necrosis EP Amaral, DL Costa, S Namasivayam, N Riteau, O Kamenyeva, ... Journal of Experimental Medicine 216 (3), 556-570, 2019 | 269 | 2019 |
| Mycobacterium tuberculosis strains of the modern sublineage of the Beijing family are more likely to display increased virulence than strains of the ancient sublineage SCM Ribeiro, LL Gomes, EP Amaral, MRM Andrade, FM Almeida, ... Journal of clinical microbiology 52 (7), 2615-2624, 2014 | 186 | 2014 |
| N-acetyl-cysteine exhibits potent anti-mycobacterial activity in addition to its known anti-oxidative functions EP Amaral, EL Conceição, DL Costa, MS Rocha, JM Marinho, ... BMC microbiology 16, 1-10, 2016 | 119 | 2016 |
| Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in aggressive forms of tuberculosis EP Amaral, SCM Ribeiro, VR Lanes, FM Almeida, MRM de Andrade, ... PLoS pathogens 10 (7), e1004188, 2014 | 97 | 2014 |
| Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by Mycobacterium tuberculosis in Infected Macrophages EP Amaral, N Riteau, M Moayeri, N Maier, KD Mayer-Barber, RM Pereira, ... Frontiers in immunology 9, 1427, 2018 | 90 | 2018 |
| Dissecting major signaling pathways throughout the development of prostate cancer HB da Silva, EP Amaral, EL Nolasco, NC de Victo, R Atique, CC Jank, ... Prostate cancer 2013, 2013 | 80 | 2013 |
| Innate immunity in tuberculosis: how the sensing of mycobacteria and tissue damage modulates macrophage death EP Amaral, EB Lasunskaia, MR D'Império-Lima Microbes and infection 18 (1), 11-20, 2016 | 71 | 2016 |
| Heme oxygenase-1 regulation of matrix metalloproteinase-1 expression underlies distinct disease profiles in tuberculosis BB Andrade, N Pavan Kumar, EP Amaral, N Riteau, KD Mayer-Barber, ... The Journal of Immunology 195 (6), 2763-2773, 2015 | 69 | 2015 |
| Nitric oxide production, inhibitory, antioxidant and antimycobacterial activities of the fruits extract and flavonoid content of Schinus terebinthifolius NR Bernardes, M Heggdorne-Araújo, IFJC Borges, FM Almeida, ... Revista Brasileira de Farmacognosia 24, 644-650, 2014 | 69 | 2014 |
| Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and-independent macrophage responses SL Lage, CL Buzzo, EP Amaral, KC Matteucci, LM Massis, MY Icimoto, ... Proceedings of the National Academy of Sciences 110 (35), E3321-E3330, 2013 | 63 | 2013 |
| Persistent Oxidative Stress and Inflammasome Activation in CD14highCD16− Monocytes From COVID-19 Patients SL Lage, EP Amaral, KL Hilligan, E Laidlaw, A Rupert, S Namasivayan, ... Frontiers in Immunology 12, 799558, 2022 | 60 | 2022 |
| P2X7 receptor drives Th1 cell differentiation and controls the follicular helper T cell population to protect against Plasmodium chabaudi malaria ÉM Salles, MN Menezes, R Siqueira, H Borges da Silva, EP Amaral, ... PLoS pathogens 13 (8), e1006595, 2017 | 55 | 2017 |
| Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes DL Costa, S Namasivayam, EP Amaral, K Arora, A Chao, LR Mittereder, ... MBio 7 (5), 10.1128/mbio. 01675-16, 2016 | 53 | 2016 |
| Pathogenic Mycobacterium bovis strains differ in their ability to modulate the proinflammatory activation phenotype of macrophages MRM Andrade, EP Amaral, SCM Ribeiro, FM Almeida, TV Peres, V Lanes, ... BMC microbiology 12, 1-12, 2012 | 49 | 2012 |
| Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes N Rockwood, DL Costa, EP Amaral, E Du Bruyn, A Kubler, L Gil-Santana, ... Frontiers in immunology 8, 542, 2017 | 48 | 2017 |
| The interplay between systemic inflammation, oxidative stress, and tissue remodeling in tuberculosis EP Amaral, CL Vinhaes, D Oliveira-de-Souza, B Nogueira, KM Akrami, ... Antioxidants & redox signaling 34 (6), 471-485, 2021 | 46 | 2021 |
| Hypervirulent Mycobacterium tuberculosis strain triggers necrotic lung pathology associated with enhanced recruitment of neutrophils in resistant C57BL/6 mice FM Almeida, TLB Ventura, EP Amaral, SCM Ribeiro, SD Calixto, ... PloS one 12 (3), e0173715, 2017 | 45 | 2017 |
| Cathepsin K contributes to cavitation and collagen turnover in pulmonary tuberculosis A Kubler, C Larsson, B Luna, BB Andrade, EP Amaral, M Urbanowski, ... The Journal of Infectious Diseases 213 (4), 618-627, 2016 | 36 | 2016 |
| Human CD40 ligand deficiency dysregulates the macrophage transcriptome causing functional defects that are improved by exogenous IFN-γ O Cabral-Marques, RN Ramos, LF Schimke, TA Khan, EP Amaral, ... Journal of Allergy and Clinical Immunology 139 (3), 900-912. e7, 2017 | 35 | 2017 |
