| The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases R Chowdhury, KK Yeoh, YM Tian, L Hillringhaus, EA Bagg, NR Rose, ... EMBO reports 12 (5), 463-469, 2011 | 1103 | 2011 |
| A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene C Church, S Lee, EAL Bagg, JS McTaggart, R Deacon, T Gerken, A Lee, ... PLoS genetics 5 (8), e1000599, 2009 | 404 | 2009 |
| 5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation RJ Hopkinson, A Tumber, C Yapp, R Chowdhury, WS Aik, KH Che, XS Li, ... Chemical Science 4 (8), 3110-3117, 2013 | 174 | 2013 |
| Structural basis for inhibition of the fat mass and obesity associated protein (FTO) WS Aik, M Demetriades, MKK Hamdan, EAL Bagg, KK Yeoh, C Lejeune, ... Journal of Medicinal Chemistry 56 (9), 3680-3688, 2013 | 151 | 2013 |
| Crystal structure of the 2-oxoglutarate-and Fe (II)-dependent lysyl hydroxylase JMJD6 M Mantri, T Krojer, EA Bagg, CJ Webby, DS Butler, G Kochan, ... Journal of molecular biology 401 (2), 211-222, 2010 | 106 | 2010 |
| Kinetic rationale for selectivity toward N-and C-terminal oxygen-dependent degradation domain substrates mediated by a loop region of hypoxia-inducible factor prolyl hydroxylases E Flashman, EAL Bagg, R Chowdhury, J Mecinović, C Loenarz, ... Journal of Biological Chemistry 283 (7), 3808-3815, 2008 | 92 | 2008 |
| Emulsion PCR Significantly Improves Nonequilibrium Capillary Electrophoresis of Equilibrium Mixtures-Based Aptamer Selection: Allowing for Efficient and Rapid Selection of … R Yufa, SM Krylova, C Bruce, EA Bagg, CJ Schofield, SN Krylov Analytical chemistry, 2014 | 83 | 2014 |
| Dynamic Combinatorial Mass Spectrometry Leads to Inhibitors of a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase ECY Woon, M Demetriades, EAL Bagg, WS Aik, SM Krylova, JHY Ma, ... Journal of Medicinal Chemistry 55 (5), 2173-2184, 2012 | 60 | 2012 |
| Performance evaluation of Sanger sequencing for the diagnosis of primary hyperoxaluria and comparison with targeted next generation sequencing EL Williams, EAL Bagg, M Mueller, J Vandrovcova, TJ Aitman, G Rumsby Molecular Genetics & Genomic Medicine 3 (1), 69-78, 2015 | 37 | 2015 |
| Specificity of localization and phosphotransfer in the CheA proteins of Rhodobacter sphaeroides KA Scott, SL Porter, EAL Bagg, R Hamer, JL Hill, DA Wilkinson, ... Molecular microbiology 76 (2), 318-330, 2010 | 35 | 2010 |
| DNA aptamers for as analytical tools for the quantitative analysis of DNA-dealkylating enzymes SM Krylova, AA Karkhanina, MU Musheev, EAL Bagg, CJ Schofield, ... Analytical Biochemistry 414 (2), 261-265, 2011 | 31 | 2011 |
| Mechanistic studies on the application of DNA aptamers as inhibitors of 2-oxoglutarate-dependent oxygenases SM Krylova, V Koshkin, E Bagg, CJ Schofield, SN Krylov Journal of medicinal chemistry 55 (7), 3546-3552, 2012 | 16 | 2012 |
| The potential of 2-oxoglutarate oxygenases acting on nucleic acids as therapeutic targets A Thalhammer, WS Aik, EAL Bagg, CJ Schofield Drug Discovery Today: Therapeutic Strategies 9 (2-3), e91-e100, 2012 | 15 | 2012 |
| Preclinical evaluation of an optimal-affinity MAGE-A4 T cell receptor for adoptive T cell therapy MM Andrew Gerry, Joseph P Sanderson, Karen Howe, Roslin Docta, Qian Gao ... Journal for ImmunoTherapy of Cancer 4 (Suppl 1), P3, 2016 | | 2016 |
| An evaluation of next generation sequencing for the genetic diagnosis of the Primary Hyperoxalurias: Th93 E Bagg, M Mueller, T Aitman, G Rumsby, E Walker Clinical Chemistry and Laboratory Medicine 52 (11), 2014 | | 2014 |
| Structural basis for inhibition of the fat mass and obesity associated protein (FTO). AWS Aik WeiShen, M Demetriades, MKK Hamdan, EAL Bagg, ... | | 2013 |
| Roles of oxygenases in nucleic acid modification EAL Bagg University of Oxford, 2011 | | 2011 |
| A dominant mutation in the obesity susceptibility gene FTO results in reduced fat mass with enhanced lipid and carbohydrate metabolism CD Church, EAL Bagg, S Lee, JS McTaggart, L Moir, R Deacon, T Gerken, ... DIABETOLOGIA 52, S90-S90, 2009 | | 2009 |
| A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene. PLoS Genet 5: e1000599 C Church, S Lee, EAL Bagg, JS Mctaggart, R Deacon, A Lee, L Moir, ... Mecinović J, Quwailid MM, Schofield CJ, Ashcroft FM, Cox RD, 2009 | | 2009 |
| Supplementary Information The Oncometabolite 2-Hydroxyglutarate Inhibits Histone Lysine Demethylases R Chowdhury, KK Yeoh, YM Tian, L Hillringhaus, EA Bagg, NR Rose, ... | | |
Michael McDonoughAtomic Resolution Consulting ABAdresse e-mail validée de atomic-resolution.com
