Chris Benner
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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
S Heinz, C Benner, N Spann, E Bertolino, YC Lin, P Laslo, JX Cheng, ...
Molecular cell 38 (4), 576-589, 2010
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
Y Zhou, B Zhou, L Pache, M Chang, AH Khodabakhshi, O Tanaseichuk, ...
Nature communications 10 (1), 1523, 2019
The selection and function of cell type-specific enhancers
S Heinz, CE Romanoski, C Benner, CK Glass
Nature reviews Molecular cell biology 16 (3), 144-154, 2015
Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA
D Wang, I Garcia-Bassets, C Benner, W Li, X Su, Y Zhou, J Qiu, W Liu, ...
Nature 474 (7351), 390-394, 2011
Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis
T Kisseleva, M Cong, YH Paik, D Scholten, C Jiang, C Benner, K Iwaisako, ...
Proceedings of the National Academy of Sciences 109 (24), 9448-9453, 2012
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors
S Ogawa, J Lozach, C Benner, G Pascual, RK Tangirala, S Westin, ...
Cell 122 (5), 707-721, 2005
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, L Pache, ...
Nature 586 (7827), 113-119, 2020
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription
MU Kaikkonen, NJ Spann, S Heinz, CE Romanoski, KA Allison, ...
Molecular cell 51 (3), 310-325, 2013
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
MTY Lam, H Cho, HP Lesch, D Gosselin, S Heinz, Y Tanaka-Oishi, ...
Nature 498 (7455), 511-515, 2013
Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
AL Hevener, JM Olefsky, D Reichart, MTA Nguyen, G Bandyopadyhay, ...
The Journal of clinical investigation 117 (6), 1658-1669, 2007
A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate
YC Lin, S Jhunjhunwala, C Benner, S Heinz, E Welinder, R Mansson, ...
Nature immunology 11 (7), 635-643, 2010
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity
S Shalapour, XJ Lin, IN Bastian, J Brain, AD Burt, AA Aksenov, ...
Nature 551 (7680), 340-345, 2017
PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression
W Liu, B Tanasa, OV Tyurina, TY Zhou, R Gassmann, WT Liu, KA Ohgi, ...
Nature 466 (7305), 508-512, 2010
Transcription elongation can affect genome 3D structure
S Heinz, L Texari, MGB Hayes, M Urbanowski, MW Chang, N Givarkes, ...
Cell 174 (6), 1522-1536. e22, 2018
Effect of natural genetic variation on enhancer selection and function
S Heinz, CE Romanoski, C Benner, KA Allison, MU Kaikkonen, ...
Nature 503 (7477), 487-492, 2013
Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors
A Crotti, C Benner, BE Kerman, D Gosselin, C Lagier-Tourenne, ...
Nature neuroscience 17 (4), 513-521, 2014
The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression
C Benner, T van der Meulen, E CacÚres, K Tigyi, CJ Donaldson, ...
BMC genomics 15 (1), 1-17, 2014
Global changes in the nuclear positioning of genes and intra-and interdomain genomic interactions that orchestrate B cell fate
YC Lin, C Benner, R Mansson, S Heinz, K Miyazaki, M Miyazaki, ...
Nature immunology 13 (12), 1196-1204, 2012
Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways
S Ghisletti, W Huang, K Jepsen, C Benner, G Hardiman, MG Rosenfeld, ...
Genes & development 23 (6), 681-693, 2009
Bcl-6 and NF-κB cistromes mediate opposing regulation of the innate immune response
GD Barish, TY Ruth, M Karunasiri, CB Ocampo, J Dixon, C Benner, ...
Genes & development 24 (24), 2760-2765, 2010
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Articles 1–20