Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway AM Taherbhoy, SW Tait, SE Kaiser, AH Williams, A Deng, A Nourse, ... Molecular cell 44 (3), 451-461, 2011 | 161 | 2011 |
Structural basis for the acyl chain selectivity and mechanism of UDP-N-acetylglucosamine acyltransferase AH Williams, CRH Raetz Proceedings of the National Academy of Sciences 104 (34), 13543-13550, 2007 | 93 | 2007 |
Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide AH Williams, RM Immormino, DT Gewirth, CRH Raetz Proceedings of the National Academy of Sciences 103 (29), 10877-10882, 2006 | 77 | 2006 |
N-terminomics identifies Prli42 as a membrane miniprotein conserved in Firmicutes and critical for stressosome activation in Listeria monocytogenes F Impens, N Rolhion, L Radoshevich, C Bécavin, M Duval, J Mellin, ... Nature microbiology 2 (5), 1-12, 2017 | 75 | 2017 |
De‐O‐acetylation of peptidoglycan regulates glycan chain extension and affects in vivo survival of Neisseria meningitidis FJ Veyrier, AH Williams, S Mesnage, C Schmitt, MK Taha, IG Boneca Molecular microbiology 87 (5), 1100-1112, 2013 | 48 | 2013 |
Enzymatic synthesis of lipid A molecules with four amide-linked acyl chains: LpxA acyltransferases selective for an analog of UDP-N-acetylglucosamine in which an amine replaces … CR Sweet, AH Williams, MJ Karbarz, C Werts, SR Kalb, RJ Cotter, ... Journal of Biological Chemistry 279 (24), 25411-25419, 2004 | 46 | 2004 |
Bulgecin A: The key to a broad-spectrum inhibitor that targets lytic transglycosylases AH Williams, R Wheeler, C Thiriau, A Haouz, MK Taha, IG Boneca Antibiotics 6 (1), 8, 2017 | 42 | 2017 |
Structural basis for the sugar nucleotide and acyl-chain selectivity of Leptospira interrogans LpxA LI Robins, AH Williams, CRH Raetz Biochemistry 48 (26), 6191-6201, 2009 | 36 | 2009 |
The cryo-electron microscopy supramolecular structure of the bacterial stressosome unveils its mechanism of activation AH Williams, A Redzej, N Rolhion, TRD Costa, A Rifflet, G Waksman, ... Nature communications 10 (1), 3005, 2019 | 28 | 2019 |
The Effect of Bulgecin A on Peptidoglycan Metabolism and Physiology of Helicobacter pylori M Bonis, A Williams, S Guadagnini, C Werts, IG Boneca Microbial drug resistance 18 (3), 230-239, 2012 | 28 | 2012 |
Structure guided design of an antibacterial peptide that targets UDP-N-acetylglucosamine acyltransferase M Dangkulwanich, CRH Raetz, AH Williams Scientific Reports 9 (1), 3947, 2019 | 24 | 2019 |
Visualization of a substrate-induced productive conformation of the catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic … AH Williams, FJ Veyrier, M Bonis, Y Michaud, B Raynal, MK Taha, ... Acta Crystallographica Section D: Biological Crystallography 70 (10), 2631-2639, 2014 | 22 | 2014 |
A step-by-step in crystallo guide to bond cleavage and 1, 6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase AH Williams, R Wheeler, L Rateau, C Malosse, J Chamot-Rooke, ... Journal of Biological Chemistry 293 (16), 6000-6010, 2018 | 18 | 2018 |
Defective lytic transglycosylase disrupts cell morphogenesis by hindering cell wall de-O-acetylation in Neisseria meningitidis AH Williams, R Wheeler, AE Deghmane, I Santecchia, RE Schaub, ... Elife 9, 2020 | 8 | 2020 |
The mechanistic landscape of lytic transglycosylase as targets for antibacterial therapy EA Martinez-Bond, BM Soriano, AH Williams Current opinion in structural biology 77, 102480, 2022 | 6 | 2022 |
The dynamics of peptidoglycan structure and function: Conference report on the 3rd Great Wall Symposium AH Williams, IG Boneca, LL Burrows, TDH Bugg Research in microbiology 165 (1), 60-67, 2014 | 2 | 2014 |
Crippling the bacterial cell wall molecular machinery AH Williams, R Wheeler, AE Deghmane, I Santecchia, F Impens, ... BioRxiv, 607697, 2019 | 1 | 2019 |
In this section J Williams Work 785, 821-0092, 2010 | 1 | 2010 |
Acetylation regulates the oligomerization state and activity of RNase J, the Helicobacter pylori major ribonuclease A Tejada-Arranz, A Lulla, M Bouilloux-Lafont, E Turlin, XY Pei, T Douché, ... Nature Communications 14 (1), 8072, 2023 | | 2023 |
Acetylation regulates the oligomerization state and activity of RNase J, the major ribonuclease of Helicobacter pylori A Tejada-Arranz, M Bouilloux-Lafont, XY Pei, T Douché, M Matondo, ... bioRxiv, 2021.08. 09.455701, 2021 | | 2021 |