Philippe Lefebvre
Philippe Lefebvre
Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, France
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Role of bile acids and bile acid receptors in metabolic regulation
P Lefebvre, B Cariou, F Lien, F Kuipers, B Staels
Physiological Reviews 89 (1), 147-191, 2009
Sorting out the roles of PPARalpha in energy metabolism and vascular homeostasis
P Lefebvre, G Chinetti, J Fruchart, B Staels
The Journal of Clinical Investigation 116 (3), 571, 2006
Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease
M Pawlak, P Lefebvre, B Staels
Journal of Hepatology 62 (3), 720-733, 2015
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator–activated receptor-γ
C Rousseaux, B Lefebvre, L Dubuquoy, P Lefebvre, O Romano, J Auwerx, ...
The Journal of Experimental Medicine 201 (8), 1205, 2005
Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease
O Chávez-Talavera, A Tailleux, P Lefebvre, B Staels
Gastroenterology 152 (7), 1679-1694. e3, 2017
Transcription factor loading on the MMTV promoter: a bimodal mechanism for promoter activation
TK Archer, P Lefebvre, RG Wolford, GL Hager
Science 255 (5051), 1573-1576, 1992
PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD
B Gross,B., Pawlak,M., Lefebvre,P., Staels
Nature Rev. Endocrino. 13 (1), 36-49, 2016
Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy.
E Woldt, Y Sebti, LA Solt, C Duhem, S Lancel, J Eeckhoute, MK Hesselink, ...
Nature Medicine 19, 1039–1046, 2013
Candida albicans phospholipomannan is sensed through toll-like receptors
T Jouault, S Ibata-Ombetta, O Takeuchi, PA Trinel, P Sacchetti, P Lefebvre, ...
Journal of Infectious Diseases 188 (1), 165-172, 2003
Retinoid X receptors: common heterodimerization partners with distinct functions
P Lefebvre, Y Benomar, B Staels
Trends in Endocrinology & Metabolism 21 (11), 676-683, 2010
Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells
MS Trabelsi, M Daoudi, J Prawitt, S Ducastel, V Touche, SI Sayin, ...
Nat. Comm. 6, 7629, 2015
Myocardial Contractile Dysfunction is Associated with Impaired Mitochondrial Function and Dynamics in Type 2 Diabetic but not in Obese Patients
B Montaigne,D, Marechal, X.,.Coisne, A., Debry, N., Modine, T., Fayad, G ...
Circulation 130, 554–564, 2014
PPARα gene expression correlates with severity and histological treatment response in patients with Non-alcoholic Steatohepatitis.
SB Francque S, Verrijken A, Caron S, Prawitt J, Paumelle R, Derudas B ...
J Hepatol. 63 (1), 164-173, 2015
Distinct but complementary contributions of PPAR isotypes to energy homeostasis.
V Dubois, J Eeckhoute, P Lefebvre, B Staels
J Clin Invest. 127 (4), 1202-1214, 2017
Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a …
D Montaigne, X Marechal, T Modine, A Coisne, S Mouton, G Fayad, ...
The Lancet 391, 59, 2017
MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids
X Fu, B Dong, Y Tian, P Lefebvre, Z Meng, X Wang, F Pattou, W Han, ...
The Journal of Clinical Investigation 125 (6), 2497-509, 2015
Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers
AA Sérandour, S Avner, F Oger, M Bizot, F Percevault, ...
Nucleic Acids Research 40 (17), 8255-8265, 2012
Transcriptional activities of retinoic acid receptors.
P Lefebvre, PJ Martin, S Flajollet, S Dedieu, X Billaut, B Lefebvre
Vitamins and hormones 70, 199-264, 2005
General Molecular Biology and Architecture of Nuclear Receptors
M Pawlak, P Lefebvre, B Staels
Current Topics in Medicinal Chemistry 12 (6), 486-504, 2012
Regulation of human ApoA-I by gemfibrozil and fenofibrate through selective peroxisome proliferator-activated receptor α modulation
H Duez, B Lefebvre, P Poulain, IP Torra, F Percevault, G Luc, JM Peters, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 25 (3), 585-591, 2005
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