Randall Duncan
Randall Duncan
Professor and Chair, Dept. of Biology, University of Michigan - Flint
Adresse e-mail validée de umich.edu
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Mechanotransduction and the functional response of bone to mechanical strain
RL Duncan, CH Turner
Calcified tissue international 57 (5), 344-358, 1995
13031995
Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain
I Owan, DB Burr, CH Turner, J Qiu, Y Tu, JE Onyia, RL Duncan
American Journal of Physiology-Cell Physiology 273 (3), C810-C815, 1997
6111997
Fluid shear-induced mechanical signaling in MC3T3-E1 osteoblasts requires cytoskeleton-integrin interactions
FM Pavalko, NX Chen, CH Turner, DB Burr, S Atkinson, YF Hsieh, J Qiu, ...
American Journal of Physiology-Cell Physiology 275 (6), C1591-C1601, 1998
5081998
The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment
K Sawakami, AG Robling, M Ai, ND Pitner, D Liu, SJ Warden, J Li, P Maye, ...
Journal of Biological Chemistry 281 (33), 23698-23711, 2006
3922006
Ca2+ regulates fluid shear-induced cytoskeletal reorganization and gene expression in osteoblasts
NX Chen, KD Ryder, FM Pavalko, CH Turner, DB Burr, J Qiu, RL Duncan
American Journal of Physiology-Cell Physiology 278 (5), C989-C997, 2000
3862000
Fluid shear‐induced ATP secretion mediates prostaglandin release in MC3T3‐E1 osteoblasts
DC Genetos, DJ Geist, D Liu, HJ Donahue, RL Duncan
Journal of Bone and Mineral Research 20 (1), 41-49, 2005
2942005
A model for mechanotransduction in bone cells: The load‐bearing mechanosomes
FM Pavalko, SM Norvell, DB Burr, CH Turner, RL Duncan, JP Bidwell
Journal of cellular biochemistry 88 (1), 104-112, 2003
2942003
Human osteoblast-like cells respond to mechanical strain with increased bone matrix protein production independent of hormonal regulation
LV Harter, KA Hruska, RL Duncan
Endocrinology 136 (2), 528-535, 1995
2721995
The P2X7 nucleotide receptor mediates skeletal mechanotransduction
J Li, D Liu, HZ Ke, RL Duncan, CH Turner
Journal of Biological Chemistry 280 (52), 42952-42959, 2005
2612005
Effects of broad frequency vibration on cultured osteoblasts
SM Tanaka, J Li, RL Duncan, H Yokota, DB Burr, CH Turner
Journal of biomechanics 36 (1), 73-80, 2003
2412003
Osteoclast cytosolic calcium, regulated by voltage-gated calcium channels and extracellular calcium, controls podosome assembly and bone resorption.
A Miyauchi, KA Hruska, EM Greenfield, R Duncan, J Alvarez, R Barattolo, ...
The Journal of cell biology 111 (6), 2543-2552, 1990
2381990
Voltage‐activated and stretch‐activated Ba2+ conducting channels in an osteoblast‐like cell line (UMR 106)
R Duncan, S Misler
Febs Letters 251 (1-2), 17-21, 1989
1831989
Do bone cells behave like a neuronal network?
CH Turner, AG Robling, RL Duncan, DB Burr
Calcified tissue international 70 (6), 435, 2002
1772002
Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca2+-and ATP-dependent in MC3T3-E1 osteoblasts
D Liu, DC Genetos, Y Shao, DJ Geist, J Li, HZ Ke, CH Turner, RL Duncan
Bone 42 (4), 644-652, 2008
1612008
Voltage-sensitive ion channels and cancer
JL Fiske, VP Fomin, ML Brown, RL Duncan, RA Sikes
Cancer and Metastasis Reviews 25 (3), 493-500, 2006
1562006
Calcium signals and calcium channels in osteoblastic cells
RL Duncan, KA Akanbi, MC Farach-Carson
Seminars in nephrology 18 (2), 178-190, 1998
1511998
Heparin-decorated, hyaluronic acid-based hydrogel particles for the controlled release of bone morphogenetic protein 2
X Xu, AK Jha, RL Duncan, X Jia
Acta biomaterialia 7 (8), 3050-3059, 2011
1402011
Structural analysis and mechanical characterization of hyaluronic acid-based doubly cross-linked networks
AK Jha, RA Hule, T Jiao, SS Teller, RJ Clifton, RL Duncan, DJ Pochan, ...
Macromolecules 42 (2), 537-546, 2009
1372009
Chronic, intermittent loading alters mechanosensitive channel characteristics in osteoblast-like cells
RL Duncan, KA Hruska
American Journal of Physiology-Renal Physiology 267 (6), F909-F916, 1994
1311994
Parathyroid hormone enhances fluid shear‐induced [Ca2+] i signaling in osteoblastic cells through activation of mechanosensitive and voltage‐sensitive Ca2+ channels
KD Ryder, RL Duncan
Journal of Bone and Mineral Research 16 (2), 240-248, 2001
1262001
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