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H.Furkan Alkan
H.Furkan Alkan
Adresse e-mail validée de utsouthwestern.edu
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Cytosolic aspartate availability determines cell survival when glutamine is limiting
HF Alkan, KE Walter, A Luengo, CT Madreiter-Sokolowski, S Stryeck, ...
Cell metabolism 28 (5), 706-720. e6, 2018
1482018
Blockade of VEGF-C and VEGF-D modulates adipose tissue inflammation and improves metabolic parameters under high-fat diet
S Karaman, M Hollmén, MR Robciuc, A Alitalo, H Nurmi, B Morf, ...
Molecular metabolism 4 (2), 93-105, 2015
1192015
PHGDH heterogeneity potentiates cancer cell dissemination and metastasis
M Rossi, P Altea-Manzano, M Demicco, G Doglioni, L Bornes, M Fukano, ...
Nature 605 (7911), 747-753, 2022
982022
Transgenic overexpression of VEGF-C induces weight gain and insulin resistance in mice
S Karaman, M Hollmén, SY Yoon, HF Alkan, K Alitalo, C Wolfrum, ...
Scientific reports 6 (1), 31566, 2016
522016
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling
P Altea-Manzano, G Doglioni, Y Liu, AM Cuadros, E Nolan, ...
Nature cancer 4 (3), 344-364, 2023
342023
Maintaining cytosolic aspartate levels is a major function of the TCA cycle in proliferating cells
HF Alkan, JG Bogner-Strauss
Molecular & Cellular Oncology 6 (5), e1536843, 2019
272019
Co-chaperone bag-1 plays a role in the autophagy-dependent cell survival through Beclin 1 interaction
M Turk, O Tatli, HF Alkan, P Ozfiliz Kilbas, G Alkurt, G Dinler Doganay
Molecules 26 (4), 854, 2021
122021
Deficiency of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis
HF Alkan, PW Vesely, H Hackl, J Foßelteder, DR Schmidt, ...
Cancer & Metabolism 8, 1-13, 2020
122020
Palmitic acid: Enabling the tumor’s nerves
HF Alkan, P Altea-Manzano, SM Fendt
Cell Metabolism 34 (1), 7-9, 2022
32022
Blockade of VEGF-C and VEGF-D modulates adipose tissue inflammation and improves metabolic parameters under high-fat diet. Mol Metab. 2014; 4 (2): 93-105
S Karaman, M Hollmén, MR Robciuc, A Alitalo, H Nurmi, B Morf, ...
3
N-acetylaspartate improves cell survival when glucose is limiting
HF Alkan, KE Walter, H Hackl, MG Vander Heiden, T Madl, ...
bioRxiv, 2020.05. 28.114629, 2020
22020
HIF1α-dependent uncoupling of glycolysis suppresses tumor cell proliferation
AA Urrutia, C Mesa-Ciller, A Guajardo-Grence, HF Alkan, I Soro-Arnáiz, ...
Cell Reports 43 (4), 2024
2024
PHGDH heterogeneity potentiates cancer cell dissemination and metastasis (vol 605. pg 747, 2022)
M Rossi, P Altea-Manzano, M Demicco, G Doglioni, L Bornes, M Fukano, ...
Nature 609 (7927), E8-E8, 2022
2022
Loss of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis
HF Alkan, PW Vesely, H Hackl, J Foßelteder, MG Vander Heiden, ...
bioRxiv, 2020.05. 29.121400, 2020
2020
Pex16 is a required factor for white adipocyte lipid and energy homeostasis
D Hofer, A Pessentheiner, HJ Pelzmann, K Huber, HF Alkan, ...
Peroxisystem 2016, 2016
2016
Characterization of N-acetyltransferase 8-like (NAT8L)-knockout mice with regard to lipid and energy homeostasis
D Hofer, HJ Pelzmann, K Huber, HF Alkan, A Pessentheiner, ...
Doctoral Day of the Medical University of Graz, 2016
2016
Pex16 is a required factor for adipocyte lipid and energy homeostasis
D Hofer, A Pessentheiner, HJ Pelzmann, K Huber, HF Alkan, ...
5th DK-MCD Scientific Retreat, 2015
2015
N-acetyltransferase 8-like (Nat8l), regulates cellular acetyl-CoA levels in brown adipocytes: Impact on energy metabolism and autophagy
K Huber, A Pessentheiner, HJ Pelzmann, D Hofer, K Dagmar, C Magnes, ...
5th DK-MCD Scientific Retreat, 2015
2015
Investigating the Role of Aspartate-Glutamate Carrier (AGC1) in Skeletal Muscle
HF Alkan, P Vesely, T Madl, E Stadelmeyer, A Pessentheiner, ...
MUG Doctoral Day, 2015
2015
The effects of VEGF-C and SIK2 on polarization and recruitment of macrophages
HF Alkan
Mühendislik ve Fen Bilimleri Enstitüsü, 2014
2014
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