Stability and Kinetics of c-MYC Promoter G-Quadruplexes Studied by Single-Molecule Manipulation H You, J Wu, F Shao, J Yan Journal of the American Chemical Society 137 (7), 2424-2427, 2015 | 96 | 2015 |
Dynamics and stability of polymorphic human telomeric G-quadruplex under tension H You, X Zeng, Y Xu, CJ Lim, AK Efremov, AT Phan, J Yan Nucleic acids research 42 (13), 8789-8795, 2014 | 83 | 2014 |
Folding/unfolding kinetics of G-quadruplexes upstream of the P1 promoter of the human BCL-2 oncogene Y Cheng, Q Tang, Y Li, Y Zhang, C Zhao, J Yan, H You Journal of Biological Chemistry 294 (15), 5890-5895, 2019 | 47 | 2019 |
Structural–elastic determination of the force-dependent transition rate of biomolecules S Guo, Q Tang, M Yao, H You, S Le, H Chen, J Yan Chemical science 9 (27), 5871-5882, 2018 | 46 | 2018 |
The mechanical properties of RNA-DNA hybrid duplex stretched by magnetic tweezers C Zhang, H Fu, Y Yang, E Zhou, Z Tan, H You, X Zhang Biophysical journal 116 (2), 196-204, 2019 | 45 | 2019 |
RHAU helicase stabilizes G4 in its nucleotide-free state and destabilizes G4 upon ATP hydrolysis H You, S Lattmann, D Rhodes, J Yan Nucleic acids research 45 (1), 206-214, 2017 | 45 | 2017 |
Single-molecule imaging and manipulation of biomolecular machines and systems R Iino, T Iida, A Nakamura, E Saita, H You, Y Sako Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (2), 241-252, 2018 | 21 | 2018 |
Torque transmission mechanism via DELSEED loop of F1-ATPase R Watanabe, K Koyasu, H You, M Tanigawara, H Noji Biophysical journal 108 (5), 1144-1152, 2015 | 20 | 2015 |
Winding single-molecule double-stranded DNA on a nanometer-sized reel H You, R Iino, R Watanabe, H Noji Nucleic acids research 40 (19), e151-e151, 2012 | 19 | 2012 |
Characterization of G-quadruplexes folding/unfolding dynamics and interactions with proteins from single-molecule force spectroscopy Y Cheng, Y Zhang, H You Biomolecules 11 (11), 1579, 2021 | 17 | 2021 |
ZYH005, a novel DNA intercalator, overcomes all-trans retinoic acid resistance in acute promyelocytic leukemia Q Tong, H You, X Chen, K Wang, W Sun, Y Pei, X Zhao, M Yuan, H Zhu, ... Nucleic Acids Research 46 (7), 3284-3297, 2018 | 13 | 2018 |
Two-state folding energy determination based on transition points in nonequilibrium single-molecule experiments H You, S Guo, S Le, Q Tang, M Yao, X Zhao, J Yan The journal of physical chemistry letters 9 (4), 811-816, 2018 | 13 | 2018 |
High mechanical stability and slow unfolding rates are prevalent in parallel-stranded DNA G-quadruplexes Y Cheng, Y Zhang, Z Gong, X Zhang, Y Li, X Shi, Y Pei, H You The Journal of Physical Chemistry Letters 11 (19), 7966-7971, 2020 | 12 | 2020 |
Detecting the formation kinetics of doxorubicin-DNA interstrand cross-link at the single-molecule level and clinically relevant concentrations of doxorubicin Y Pei, Y Liu, C Xie, X Zhang, H You Analytical chemistry 92 (6), 4504-4511, 2020 | 12 | 2020 |
Mechanical diversity and folding intermediates of parallel-stranded G-quadruplexes with a bulge Y Zhang, Y Cheng, J Chen, K Zheng, H You Nucleic Acids Research 49 (12), 7179-7188, 2021 | 11 | 2021 |
A universal assay for making DNA, RNA, and RNA–DNA hybrid configurations for single-molecule manipulation in two or three steps without ligation YJ Yang, L Song, XC Zhao, C Zhang, WQ Wu, HJ You, H Fu, EC Zhou, ... ACS Synthetic Biology 8 (7), 1663-1672, 2019 | 11 | 2019 |
The holdase function of Escherichia coli Hsp70 (DnaK) chaperone RS Winardhi, Q Tang, H You, M Sheetz, J Yan bioRxiv, 305854, 2018 | 9 | 2018 |
Single-molecule manipulation of G-quadruplexes by magnetic tweezers H You, S Le, H Chen, L Qin, J Yan JoVE (Journal of Visualized Experiments), e56328, 2017 | 8 | 2017 |
Using magnetic tweezers to unravel the mechanism of the G-quadruplex binding and unwinding activities of DHX36 helicase H You, Y Zhou, J Yan RNA Remodeling Proteins: Methods and Protocols, 175-191, 2021 | 5 | 2021 |
Single-molecule mechanical unfolding of AT-rich chromosomal fragile site DNA hairpins: resolving the thermodynamic and kinetic effects of a single GT mismatch X Li, Y Pei, Y Zhang, Y Liu, W Fu, J Li, H You, J Huang The Journal of Physical Chemistry B 124 (42), 9365-9370, 2020 | 5 | 2020 |