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Leslie O. Ofori
Leslie O. Ofori
Adresse e-mail validée de stanford.edu
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Design of protease activated optical contrast agents that exploit a latent lysosomotropic effect for use in fluorescence-guided surgery
LO Ofori, NP Withana, TR Prestwood, M Verdoes, JJ Brady, MM Winslow, ...
ACS chemical biology 10 (9), 1977-1988, 2015
1122015
Non-invasive imaging of idiopathic pulmonary fibrosis using cathepsin protease probes
NP Withana, X Ma, HM McGuire, M Verdoes, WA van der Linden, LO Ofori, ...
Scientific reports 6 (1), 19755, 2016
992016
From dynamic combinatorial ‘hit’ to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy
LO Ofori, J Hoskins, M Nakamori, CA Thornton, BL Miller
Nucleic acids research 40 (13), 6380-6390, 2012
812012
Design of a highly selective quenched activity-based probe and its application in dual color imaging studies of cathepsin S activity localization
K Oresic Bender, L Ofori, WA van der Linden, ED Mock, GK Datta, ...
Journal of the American Chemical Society 137 (14), 4771-4777, 2015
742015
Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion
MA Child, CI Hall, JR Beck, LO Ofori, VE Albrow, M Garland, PW Bowyer, ...
Nature chemical biology 9 (10), 651-656, 2013
692013
Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects
JW Hoskins, LO Ofori, CZ Chen, A Kumar, K Sobczak, M Nakamori, ...
Nucleic acids research 42 (10), 6591-6602, 2014
622014
Labeling of active proteases in fresh-frozen tissues by topical application of quenched activity-based probes
NP Withana, M Garland, M Verdoes, LO Ofori, E Segal, M Bogyo
Nature protocols 11 (1), 184-191, 2016
562016
High-affinity recognition of HIV-1 frameshift-stimulating RNA alters frameshifting in vitro and interferes with HIV-1 infectivity
LO Ofori, TA Hilimire, RP Bennett, NW Brown Jr, HC Smith, BL Miller
Journal of Medicinal Chemistry 57 (3), 723-732, 2014
512014
Dual-modality activity-based probes as molecular imaging agents for vascular inflammation
NP Withana, T Saito, X Ma, M Garland, C Liu, H Kosuge, M Amsallem, ...
Journal of Nuclear Medicine 57 (10), 1583-1590, 2016
462016
Strategies for Recognition of Stem− Loop RNA Structures by Synthetic Ligands: Application to the HIV-1 Frameshift Stimulatory Sequence
PB Palde, LO Ofori, PC Gareiss, J Lerea, BL Miller
Journal of medicinal chemistry 53 (16), 6018-6027, 2010
402010
Nucleic acid binding compounds, methods of making, and use thereof
BL Miller, LO Ofori, AV Gromova
US Patent App. 13/976,852, 2014
32014
Solving the problem of sequence selective RNA recognition by small molecules with application to Myotonic Dystrophy and HIV
LO Ofori
University of Rochester, 2012
12012
Protease-activated contrast agents for in vivo imaging
MS Bogyo, M Verdoes, L Ofori, NP Withana
US Patent App. 18/489,653, 2024
2024
Protease-activated contrast agents for in vivo imaging
MS Bogyo, M Verdoes, L Ofori, NP Withana
US Patent App. 18/053,682, 2024
2024
Protease-activated contrast agents for in vivo imaging
MS Bogyo, M Verdoes, L Ofori, NP Withana
US Patent 11,828,752, 2023
2023
CONTRAST AGENTS ACTIVATED BY A PROTEASE FOR IN VIVO IMAGING
MS Bogyo, M VERDOES, L OFORI, NP WITHANA
2021
Protease-activated contrast agents for in vivo imaging
MS Bogyo, M Verdoes, L Ofori, NP Withana
US Patent App. 16/792,142, 2020
2020
Protease-activated contrast agents for in vivo imaging
MS Bogyo, M Verdoes, L Ofori, NP Withana
US Patent 10,570,173, 2020
2020
Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease Probes
H Collard, P Wolters, NP Withana, X Ma, HM McGuire, M Verdoes, ...
2016
New chemical probe technologies for diagnostic and intra-operative imaging applications
L Ofori, N Withana, M Verdoes, J Sorger, M Bogyo
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015
2015
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