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Antonio DiGiandomenico
Antonio DiGiandomenico
Verified email at astrazeneca.com
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Cited by
Year
A multifunctional bispecific antibody protects against Pseudomonas aeruginosa
A DiGiandomenico, AE Keller, C Gao, GJ Rainey, P Warrener, ...
Science translational medicine 6 (262), 262ra155-262ra155, 2014
2762014
Patrolling alveolar macrophages conceal bacteria from the immune system to maintain homeostasis
AS Neupane, M Willson, AK Chojnacki, FVES Castanheira, C Morehouse, ...
Cell 183 (1), 110-125. e11, 2020
1972020
Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening
A Digiandomenico, P Warrener, M Hamilton, S Guillard, P Ravn, R Minter, ...
Journal of Experimental Medicine 209 (7), 1273-1287, 2012
1892012
Neutrophil extracellular traps confine Pseudomonas aeruginosa ocular biofilms and restrict brain invasion
A Thanabalasuriar, BNV Scott, M Peiseler, ME Willson, Z Zeng, ...
Cell host & microbe 25 (4), 526-536. e4, 2019
1542019
A novel anti-PcrV antibody providing enhanced protection against Pseudomonas aeruginosa in multiple animal infection models
P Warrener, R Varkey, JC Bonnell, A DiGiandomenico, M Camara, ...
Antimicrobial agents and chemotherapy 58 (8), 4384-4391, 2014
1272014
Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections
TS Cohen, JJ Hilliard, O Jones-Nelson, AE Keller, T O’Day, C Tkaczyk, ...
Science Translational Medicine 8 (329), 329ra31-329ra31, 2016
1142016
Glycosylation of Pseudomonas aeruginosa 1244 pilin: glycan substrate specificity
A DiGiandomenico, MJ Matewish, A Bisaillon, JR Stehle, JS Lam, ...
Molecular microbiology 46 (2), 519-530, 2002
1092002
Phase 1 study of MEDI3902, an investigational anti–Pseudomonas aeruginosa PcrV and Psl bispecific human monoclonal antibody, in healthy adults
SO Ali, XQ Yu, GJ Robbie, Y Wu, K Shoemaker, L Yu, A DiGiandomenico, ...
Clinical microbiology and infection 25 (5), 629. e1-629. e6, 2019
1082019
Antibacterial monoclonal antibodies: the next generation?
A DiGiandomenico, BR Sellman
Current opinion in microbiology 27, 78-85, 2015
1052015
Intranasal immunization with heterologously expressed polysaccharide protects against multiple Pseudomonas aeruginosa infections
A DiGiandomenico, J Rao, K Harcher, TS Zaidi, J Gardner, AN Neely, ...
Proceedings of the National Academy of Sciences 104 (11), 4624-4629, 2007
882007
Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature
A Thanabalasuriar, BGJ Surewaard, ME Willson, AS Neupane, CK Stover, ...
The Journal of clinical investigation 127 (6), 2249-2261, 2017
872017
Suppression of acute lung inflammation by intracellular peptide delivery of a nuclear import inhibitor
D Liu, J Zienkiewicz, A DiGiandomenico, J Hawiger
Molecular Therapy 17 (5), 796-802, 2009
832009
Oral Vaccination of BALB/c Mice with Salmonella enterica Serovar Typhimurium Expressing Pseudomonas aeruginosa O Antigen Promotes Increased Survival in …
A DiGiandomenico, J Rao, JB Goldberg
Infection and immunity 72 (12), 7012-7021, 2004
812004
Immune stealth-driven O2 serotype prevalence and potential for therapeutic antibodies against multidrug resistant Klebsiella pneumoniae
ME Pennini, A De Marco, M Pelletier, J Bonnell, R Cvitkovic, ...
Nature communications 8 (1), 1991, 2017
772017
An engineered bispecific DNA-encoded IgG antibody protects against Pseudomonas aeruginosa in a pneumonia challenge model
A Patel, A DiGiandomenico, AE Keller, TRF Smith, DH Park, S Ramos, ...
Nature communications 8 (1), 637, 2017
602017
Lipopolysaccharide O-Antigen Chain Length Regulation in Pseudomonas aeruginosa Serogroup O11 Strain PA103
E Kintz, JM Scarff, A DiGiandomenico, JB Goldberg
Journal of bacteriology 190 (8), 2709-2716, 2008
552008
Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates
DE Tabor, V Oganesyan, AE Keller, L Yu, RE McLaughlin, E Song, ...
The Journal of Infectious Diseases 218 (12), 1983-1994, 2018
512018
Anti-Psl Targeting of Pseudomonas aeruginosa Biofilms for Neutrophil-Mediated Disruption
VA Ray, PJ Hill, CK Stover, S Roy, CK Sen, L Yu, DJ Wozniak, ...
Scientific reports 7 (1), 16065, 2017
472017
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient
J Rao, FH Damron, M Basler, A DiGiandomenico, NE Sherman, JW Fox, ...
Frontiers in microbiology 2, 162, 2011
442011
A novel oxidized low-density lipoprotein-binding protein from Pseudomonas aeruginosa
J Rao, A DiGiandomenico, J Unger, Y Bao, RK Polanowska-Grabowska, ...
Microbiology 154 (2), 654-665, 2008
442008
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