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Ali Tavassoli
Ali Tavassoli
Professor of Chemical Biology at University of Southampton and CSO of Curve Therapeutics
Adresse e-mail validée de soton.ac.uk - Page d'accueil
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A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells
E Miranda, IK Nordgren, AL Male, CE Lawrence, F Hoakwie, F Cuda, ...
Journal of the American Chemical Society 135 (28), 10418-10425, 2013
208*2013
Biocompatible artificial DNA linker that is read through by DNA polymerases and is functional in Escherichia coli
AH El-Sagheer, AP Sanzone, R Gao, A Tavassoli, T Brown
Proceedings of the National Academy of Sciences 108 (28), 11338-11343, 2011
2062011
Split-intein mediated circular ligation used in the synthesis of cyclic peptide libraries in E. coli
A Tavassoli, SJ Benkovic
Nature protocols 2 (5), 1126-1133, 2007
2012007
Inhibition of HIV Budding by a Genetically Selected Cyclic Peptide Targeting the Gag− TSG101 Interaction
A Tavassoli, Q Lu, J Gam, H Pan, SJ Benkovic, SN Cohen
ACS chemical biology 3 (12), 757-764, 2008
1872008
Identification of borinic esters as inhibitors of bacterial cell growth and bacterial methyltransferases, CcrM and MenH
SJ Benkovic, SJ Baker, MRK Alley, YH Woo, YK Zhang, T Akama, W Mao, ...
Journal of medicinal chemistry 48 (23), 7468-7476, 2005
1622005
Methods for generating and screening libraries of genetically encoded cyclic peptides in drug discovery
C Sohrabi, A Foster, A Tavassoli
Nature Reviews Chemistry 4 (2), 90-101, 2020
1392020
A lanthipeptide library used to identify a protein–protein interaction inhibitor
X Yang, KR Lennard, C He, MC Walker, AT Ball, C Doigneaux, ...
Nature Chemical Biology 14 (4), 375-380, 2018
1292018
SICLOPPS cyclic peptide libraries in drug discovery
A Tavassoli
Current Opinion in Chemical Biology 38, 30-35, 2017
1272017
Genetically selected cyclic‐peptide inhibitors of AICAR transformylase homodimerization
A Tavassoli, SJ Benkovic
Angewandte Chemie International Edition 44 (18), 2760-2763, 2005
1262005
Targeting Tumour Proliferation with a Small‐Molecule Inhibitor of AICAR Transformylase Homodimerization
IB Spurr, CN Birts, F Cuda, SJ Benkovic, JP Blaydes, A Tavassoli
ChemBioChem 13 (11), 1628-1634, 2012
1112012
Transcription of Click‐Linked DNA in Human Cells
CN Birts, AP Sanzone, AH El‐Sagheer, JP Blaydes, T Brown, A Tavassoli
Angewandte Chemie International Edition 53 (9), 2362-2365, 2014
982014
Targeting tumour angiogenesis with small molecule inhibitors of hypoxia inducible factor
IK Nordgren, A Tavassoli
Chemical Society Reviews 40 (8), 4307-4317, 2011
932011
A cyclic peptide inhibitor of C-terminal binding protein dimerization links metabolism with mitotic fidelity in breast cancer cells
CN Birts, SK Nijjar, CA Mardle, F Hoakwie, PJ Duriez, JP Blaydes, ...
Chemical Science 4 (8), 3046-3057, 2013
902013
AMPK Activation via Modulation of De Novo Purine Biosynthesis with an Inhibitor of ATIC Homodimerization
DJ Asby, F Cuda, M Beyaert, FD Houghton, FR Cagampang, A Tavassoli
Chemistry & biology 22 (7), 838-848, 2015
852015
Assembly of a biocompatible triazole-linked gene by one-pot click-DNA ligation
NM Kukwikila, N Gale, AH El-Sagheer, T Brown, A Tavassoli
Nature Chemistry, 2017
832017
Peptides Come Round: Using SICLOPPS Libraries for Early Stage Drug Discovery
KR Lennard, A Tavassoli
Chemistry-A European Journal 20 (34), 10608-10614, 2014
802014
Influenza A/Hong Kong/156/1997 (H5N1) virus NS1 gene mutations F103L and M106I both increase IFN antagonism, virulence and cytoplasmic localization but differ in binding to RIG …
SK Dankar, E Miranda, NE Forbes, M Pelchat, A Tavassoli, M Selman, ...
Virology journal 10 (1), 243, 2013
612013
Rational design, synthesis, evaluation, and crystal structure of a potent inhibitor of human GAR Tfase: 10-(trifluoroacetyl)-5, 10-dideazaacyclic-5, 6, 7, 8-tetrahydrofolic acid
Y Zhang, J Desharnais, TH Marsilje, C Li, MP Hedrick, LT Gooljarsingh, ...
Biochemistry 42 (20), 6043-6056, 2003
592003
Fluorescent transmembrane anion transporters: shedding light on anionophoric activity in cells
SN Berry, V Soto-Cerrato, ENW Howe, HJ Clarke, I Mistry, A Tavassoli, ...
Chemical Science 7 (8), 5069-5077, 2016
572016
Genetic selection of cyclic peptide Dam methyltransferase inhibitors
TA Naumann, A Tavassoli, SJ Benkovic
ChemBioChem 9 (2), 194-197, 2008
572008
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