| Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage S Alsafadi, A Houy, A Battistella, T Popova, M Wassef, E Henry, F Tirode, ... Nature communications 7 (1), 10615, 2016 | 392 | 2016 |
| Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib L Quek, MD David, A Kennedy, M Metzner, M Amatangelo, A Shih, ... Nature medicine 24 (8), 1167-1177, 2018 | 178 | 2018 |
| Targeting the deregulated spliceosome core machinery in cancer cells triggers mTOR blockade and autophagy V Quidville, S Alsafadi, A Goubar, F Commo, V Scott, C Pioche-Durieu, ... Cancer research 73 (7), 2247-2258, 2013 | 160 | 2013 |
| A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome S Bondu, AS Alary, C Lefèvre, A Houy, G Jung, T Lefebvre, D Rombaut, ... Science Translational Medicine 11 (500), eaav5467, 2019 | 73 | 2019 |
| Chk1 as a new therapeutic target in triple-negative breast cancer L Albiges, A Goubar, V Scott, C Vicier, C Lefèbvre, S Alsafadi, F Commo, ... The Breast 23 (3), 250-258, 2014 | 60 | 2014 |
| Germline MBD4 Mutations and Predisposition to Uveal Melanoma AC Derrien, M Rodrigues, A Eeckhoutte, S Dayot, A Houy, L Mobuchon, ... JNCI: Journal of the National Cancer Institute 113 (1), 80-87, 2021 | 55 | 2021 |
| Evolutionary Routes in Metastatic Uveal Melanomas Depend on MBD4 Alterations M Rodrigues, L Mobuchon, A Houy, S Alsafadi, S Baulande, O Mariani, ... Clinical Cancer Research 25 (18), 5513-5524, 2019 | 54 | 2019 |
| Splicing Patterns in SF3B1-Mutated Uveal Melanoma Generate Shared Immunogenic Tumor-Specific Neoepitopes J Bigot, AI Lalanne, F Lucibello, P Gueguen, A Houy, S Dayot, O Ganier, ... Cancer discovery 11 (8), 1938-1951, 2021 | 50 | 2021 |
| Emerging therapeutic opportunities based on current knowledge of uveal melanoma biology R Vivet-Noguer, M Tarin, S Roman-Roman, S Alsafadi Cancers 11 (7), 1019, 2019 | 42 | 2019 |
| Angiotropism and extravascular migratory metastasis in cutaneous and uveal melanoma progression in a zebrafish model G Fornabaio, RL Barnhill, C Lugassy, LA Bentolila, N Cassoux, ... Scientific reports 8 (1), 10448, 2018 | 42 | 2018 |
| P53 family: at the crossroads in cancer therapy S Alsafadi, S Tourpin, F André, G Vassal, JC Ahomadegbe Current medicinal chemistry 16 (32), 4328-4344, 2009 | 42 | 2009 |
| Preclinical evaluation of drug combinations identifies co-inhibition of Bcl-2/XL/W and MDM2 as a potential therapy in uveal melanoma D Decaudin, EFD Leitz, F Nemati, M Tarin, A Naguez, M Zerara, ... European Journal of Cancer 126, 93-103, 2020 | 26 | 2020 |
| Retinoic acid receptor alpha amplifications and retinoic acid sensitivity in breast cancers S Alsafadi, C Even, C Falet, A Goubar, F Commo, V Scott, V Quidville, ... Clinical breast cancer 13 (5), 401-408, 2013 | 26 | 2013 |
| Genetic alterations of SUGP1 mimic mutant-SF3B1 splice pattern in lung adenocarcinoma and other cancers S Alsafadi, S Dayot, M Tarin, A Houy, D Bellanger, M Cornella, M Wassef, ... Oncogene 40 (1), 85-96, 2021 | 21 | 2021 |
| Involvement of N-terminally truncated variants of p73, ΔTAp73, in head and neck squamous cell cancer: A comparison with p53 mutations L Faridoni-Laurens, S Tourpin, S Alsafadi, M Barrois, S Temam, F Janot, ... Cell Cycle 7 (11), 1587-1596, 2008 | 19 | 2008 |
| Functional and conformational impact of cancer-associated SF3B1 mutations depends on the position and the charge of amino acid substitution C Canbezdi, M Tarin, A Houy, D Bellanger, T Popova, MH Stern, ... Computational and Structural Biotechnology Journal 19, 1361-1370, 2021 | 15 | 2021 |
| Differential expression of DNA repair genes in prognostically-favorable versus unfavorable uveal melanoma M Dogrusöz, A Ruschel Trasel, J Cao, S Ҫolak, SI van Pelt, WGM Kroes, ... Cancers 11 (8), 1104, 2019 | 15 | 2019 |
| SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response P Bland, H Saville, PT Wai, L Curnow, G Muirhead, J Nieminuszczy, ... Nature Genetics 55 (8), 1311-1323, 2023 | 8 | 2023 |
| Nuclear localization of the caspase-3-cleaved form of p73 in anoikis S Alsafadi, S Tourpin, N Bessoltane, S Salomé-Desnoulez, G Vassal, ... Oncotarget 7 (11), 12331, 2016 | 8 | 2016 |
| Patient-derived zebrafish xenografts of uveal melanoma reveal ferroptosis as a drug target A Groenewoud, J Yin, MC Gelmi, S Alsafadi, F Nemati, D Decaudin, ... Cell Death Discovery 9 (1), 183, 2023 | 7 | 2023 |
