Bruno Villoutreix
Bruno Villoutreix
Adresse e-mail validée de inserm.fr - Page d'accueil
TitreCitée parAnnée
Regulation of blood coagulation by the protein C anticoagulant pathway: novel insights into structure-function relationships and molecular recognition
B Dahlbäck, BO Villoutreix
Arteriosclerosis, thrombosis, and vascular biology 25 (7), 1311-1320, 2005
2852005
The anticoagulant protein C pathway
B Dahlbäck, BO Villoutreix
FEBS letters 579 (15), 3310-3316, 2005
2722005
Druggable pockets and binding site centric chemical space: a paradigm shift in drug discovery
S Perot, O Sperandio, MA Miteva, AC Camproux, BO Villoutreix
Drug discovery today 15 (15-16), 656-667, 2010
2222010
FAF-Drugs2: free ADME/tox filtering tool to assist drug discovery and chemical biology projects
D Lagorce, O Sperandio, H Galons, MA Miteva, BO Villoutreix
BMC bioinformatics 9 (1), 396, 2008
2022008
Complement inhibitor C4b-binding protein—friend or foe in the innate immune system?
AM Blom, BO Villoutreix, B Dahlbäck
Molecular immunology 40 (18), 1333-1346, 2004
1942004
3-Dimensional structure of membrane-bound coagulation factor VIII: modeling of the factor VIII heterodimer within a 3-dimensional density map derived by electron crystallography
S Stoilova-McPhie, BO Villoutreix, K Mertens, G Kemball-Cook, ...
Blood 99 (4), 1215-1223, 2002
1832002
Rationalizing the chemical space of protein–protein interaction inhibitors
O Sperandio, CH Reynès, AC Camproux, BO Villoutreix
Drug discovery today 15 (5-6), 220-229, 2010
1612010
Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome
F Bienaime, MA Dragon-Durey, CH Regnier, SC Nilsson, WH Kwan, ...
Kidney international 77 (4), 339-349, 2010
1552010
A novel interaction of outer membrane protein A with C4b binding protein mediates serum resistance of Escherichia coli K1
NV Prasadarao, AM Blom, BO Villoutreix, LC Linsangan
The Journal of Immunology 169 (11), 6352-6360, 2002
1552002
Toward in silico structure-based ADMET prediction in drug discovery
G Moroy, VY Martiny, P Vayer, BO Villoutreix, MA Miteva
Drug discovery today 17 (1-2), 44-55, 2012
1492012
FAF-Drugs3: a web server for compound property calculation and chemical library design
D Lagorce, O Sperandio, JB Baell, MA Miteva, BO Villoutreix
Nucleic acids research 43 (W1), W200-W207, 2015
1432015
Structure-based virtual ligand screening: recent success stories
BO Villoutreix, R Eudes, MA Miteva
Combinatorial chemistry & high throughput screening 12 (10), 1000-1016, 2009
1382009
Fast structure-based virtual ligand screening combining FRED, DOCK, and Surflex
MA Miteva, WH Lee, MO Montes, BO Villoutreix
Journal of medicinal chemistry 48 (19), 6012-6022, 2005
1282005
Proposed lipocalin fold for apolipoprotein M based on bioinformatics and site‐directed mutagenesis
J Duan, B Dahlbäck, BO Villoutreix
FEBS letters 499 (1-2), 127-132, 2001
1222001
A cluster of positively charged amino acids in the C4BP α-chain is crucial for C4b binding and factor I cofactor function
AM Blom, J Webb, BO Villoutreix, B Dahlbäck
Journal of Biological Chemistry 274 (27), 19237-19245, 1999
1071999
Free resources to assist structure-based virtual ligand screening experiments
BO Villoutreix, N Renault, D Lagorce, O Sperandio, M Montes, MA Miteva
Current Protein and Peptide Science 8 (4), 381-411, 2007
1052007
A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells
A Säfholm, K Leandersson, J Dejmek, CK Nielsen, BO Villoutreix, ...
Journal of Biological Chemistry 281 (5), 2740-2749, 2006
1052006
Designing focused chemical libraries enriched in protein-protein interaction inhibitors using machine-learning methods
C Reynès, H Host, AC Camproux, G Laconde, F Leroux, A Mazars, ...
PLoS computational biology 6 (3), e1000695, 2010
992010
FAF-Drugs: free ADME/tox filtering of compound collections
MA Miteva, S Violas, M Montes, D Gomez, P Tuffery, BO Villoutreix
Nucleic acids research 34 (suppl_2), W738-W744, 2006
982006
Molecular recognition in the protein C anticoagulant pathway
B Dahlbäck, BO Villoutreix
Journal of thrombosis and haemostasis 1 (7), 1525-1534, 2003
942003
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