Leopold Parts
Leopold Parts
Faculty at Wellcome Sanger Institute; Senior Researcher (part-time) at University of Tartu
Adresse e-mail validée de sanger.ac.uk - Page d'accueil
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A map of human genome variation from population scale sequencing
1000 Genomes Project Consortium
Nature 467 (7319), 1061, 2010
75782010
Evolution of genes and genomes on the Drosophila phylogeny
AG Clark, MB Eisen, DR Smith, CM Bergman, B Oliver, TA Markow, ...
Nature 450 (7167), 203-218, 2007
20462007
Population genomics of domestic and wild yeasts
D Carter, G Liti, A Moses, L Parts, S James, R Davey, I Roberts, ...
Nature, 2009
1472*2009
Deep learning for computational biology
C Angermueller, T Pärnamaa, L Parts, O Stegle
Molecular systems biology 12 (7), 878, 2016
9822016
Mapping cis-and trans-regulatory effects across multiple tissues in twins
E Grundberg, KS Small, ÅK Hedman, AC Nica, A Buil, S Keildson, JT Bell, ...
Nature genetics 44 (10), 1084-1089, 2012
7752012
Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures
A Stark, MF Lin, P Kheradpour, JS Pedersen, L Parts, JW Carlson, ...
Nature 450 (7167), 219-232, 2007
6762007
Using Probabilistic Estimation of Expression Residuals (PEER) to obtain increased power and interpretability of gene expression analyses
O Stegle, L Parts, M Piipari, J Winn, R Durbin
Nature Protocols 7 (3), 500-507, 2012
6292012
Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants
GC Langridge, MD Phan, DJ Turner, TT Perkins, L Parts, J Haase, ...
Genome research 19 (12), 2308-2316, 2009
5412009
Patterns of Cis Regulatory Variation in Diverse Human Populations
BE Stranger, SB Montgomery, AS Dimas, L Parts, O Stegle, CE Ingle, ...
PLoS genetics 8 (4), e1002639, 2012
5202012
The architecture of gene regulatory variation across multiple human tissues: the MuTHER study
AC Nica, L Parts, D Glass, J Nisbet, A Barrett, M Sekowska, M Travers, ...
PLoS genetics 7 (2), e1002003, 2011
5012011
A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies
O Stegle, L Parts, R Durbin, J Winn
PLoS computational biology 6 (5), e1000770, 2010
4082010
Functional profiling of a Plasmodium genome reveals an abundance of essential genes
E Bushell, AR Gomes, T Sanderson, B Anar, G Girling, C Herd, T Metcalf, ...
Cell 170 (2), 260-272. e8, 2017
3312017
A high-definition view of functional genetic variation from natural yeast genomes
A Bergström, JT Simpson, F Salinas, B Barré, L Parts, A Zia, ...
Molecular biology and evolution 31 (4), 872-888, 2014
2622014
Revealing the genetic structure of a trait by sequencing a population under selection
L Parts, FA Cubillos, J Warringer, K Jain, F Salinas, SJ Bumpstead, ...
Genome research 21 (7), 1131-1138, 2011
2482011
Predicting the mutations generated by repair of Cas9-induced double-strand breaks
F Allen, L Crepaldi, C Alsinet, AJ Strong, V Kleshchevnikov, P De Angeli, ...
Nature biotechnology 37 (1), 64-72, 2019
2432019
Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes
A Stark, P Kheradpour, L Parts, J Brennecke, E Hodges, GJ Hannon, ...
Genome research 17 (12), 1865-1879, 2007
2172007
Gene expression changes with age in skin, adipose tissue, blood and brain
D Glass, A Viñuela, MN Davies, A Ramasamy, L Parts, D Knowles, ...
Genome biology 14 (7), 1-12, 2013
2152013
The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis
M van de Bunt, KJ Gaulton, L Parts, I Moran, PR Johnson, CM Lindgren, ...
PloS one 8 (1), e55272, 2013
1882013
Assessing the complex architecture of polygenic traits in diverged yeast populations
FA Cubillos, E Billi, E Zörgö, L Parts, P Fargier, S Omholt, A Blomberg, ...
Molecular ecology 20 (7), 1401-1413, 2011
1812011
Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design
JD Smith, S Suresh, U Schlecht, M Wu, O Wagih, G Peltz, RW Davis, ...
Genome biology 17 (1), 1-16, 2016
1332016
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