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Alexandre Quintas
Alexandre Quintas
Professor of Biochemistry, Egas Moniz
Adresse e-mail validée de egasmoniz.edu.pt
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Tetramer dissociation and monomer partial unfolding precedes protofibril formation in amyloidogenic transthyretin variants
A Quintas, DC Vaz, I Cardoso, MJM Saraiva, RMM Brito
Journal of Biological Chemistry 276 (29), 27207-27213, 2001
4052001
Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation
MJ Diógenes, RB Dias, DM Rombo, HV Miranda, F Maiolino, P Guerreiro, ...
Journal of Neuroscience 32 (34), 11750-11762, 2012
2942012
The tetrameric protein transthyretin dissociates to a non-native monomer in solution: a novel model for amyloidogenesis
A Quintas, MJM Saraiva, RMM Brito
Journal of Biological Chemistry 274 (46), 32943-32949, 1999
2081999
Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies
H Vicente Miranda, ÉM Szegő, LMA Oliveira, C Breda, E Darendelioglu, ...
Brain 140 (5), 1399-1419, 2017
2012017
The amyloidogenic potential of transthyretin variants correlates with their tendency to aggregate in solution
A Quintas, MJM Saraiva, RMM Brito
Febs Letters 418 (3), 297-300, 1997
1291997
Insulin glycation by methylglyoxal results in native-like aggregation and inhibition of fibril formation
LMA Oliveira, A Lages, RA Gomes, H Neves, C Família, AV Coelho, ...
BMC biochemistry 12, 1-13, 2011
1242011
Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy
R Gomes, M Sousa Silva, A Quintas, C Cordeiro, A Freire, P Pereira, ...
Biochemical Journal 385 (2), 339-345, 2005
1222005
Dopamine-induced conformational changes in alpha-synuclein
TF Outeiro, J Klucken, K Bercury, J Tetzlaff, P Putcha, LMA Oliveira, ...
PloS one 4 (9), e6906, 2009
852009
Prediction of peptide and protein propensity for amyloid formation
C Família, SR Dennison, A Quintas, DA Phoenix
PloS one 10 (8), e0134679, 2015
692015
Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the homotetrameric protein transthyretin
VL Shnyrov, E Villar, GG Zhadan, JM Sanchez-Ruiz, A Quintas, ...
Biophysical Chemistry 88 (1-3), 61-67, 2000
652000
Insights into the molecular mechanism of protein native-like aggregation upon glycation
LMA Oliveira, RA Gomes, D Yang, SR Dennison, C Família, A Lages, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (6), 1010-1022, 2013
632013
Bioquimica-organização molecular da vida
A Quintas, AP Freire, MJ Halpern
Lisboa: Lidel, 2008
622008
Protein glycation in vivo: functional and structural effects on yeast enolase
RA Gomes, LMA Oliveira, M Silva, C Ascenso, A Quintas, G Costa, ...
Biochemical journal 416 (3), 317-326, 2008
612008
Energy-independent translocation of cell-penetrating peptides occurs without formation of pores. A biophysical study with pep-1
S Troeira Henriques, A Quintas, LA Bagatolli, F Homblé, MARB Castanho
Molecular membrane biology 24 (4), 282-293, 2007
592007
Probing Surface Properties of Cytochrome c at Au Bionanoconjugates
I Gomes, NC Santos, LMA Oliveira, A Quintas, P Eaton, E Pereira, ...
The Journal of Physical Chemistry C 112 (42), 16340-16347, 2008
492008
Evolutionary and structural features of the C2, V3 and C3 envelope regions underlying the differences in HIV-1 and HIV-2 biology and infection
H Barroso, P Borrego, I Bártolo, JM Marcelino, C Família, A Quintas, ...
PloS one 6 (1), e14548, 2011
472011
An ancestral HIV-2/simian immunodeficiency virus peptide with potent HIV-1 and HIV-2 fusion inhibitor activity
P Borrego, R Calado, JM Marcelino, P Pereira, A Quintas, H Barroso, ...
Aids 27 (7), 1081-1090, 2013
372013
Potent and broadly reactive HIV-2 neutralizing antibodies elicited by a vaccinia virus vector prime-C2V3C3 polypeptide boost immunization strategy
JM Marcelino, P Borrego, C Rocha, H Barroso, A Quintas, C Novo, ...
Journal of virology 84 (23), 12429-12436, 2010
362010
Resistance to antibody neutralization in HIV-2 infection occurs in late stage disease and is associated with X4 tropism
JM Marcelino, P Borrego, C Nilsson, C Família, H Barroso, F Maltez, ...
Aids 26 (18), 2275-2284, 2012
352012
Extraction procedures for hair forensic toxicological analysis: a mini-review
C Ferreira, C Paulino, A Quintas
Chemical research in toxicology 32 (12), 2367-2381, 2019
342019
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