Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ-Aminobutyric Acid Aminotransferase Inactivator … JI Juncosa, K Takaya, HV Le, MJ Moschitto, PM Weerawarna, ... Journal of the American Chemical Society 140 (6), 2151-2164, 2018 | 70 | 2018 |
Structural and biochemical characterization of AidC, a quorum-quenching lactonase with atypical selectivity R Mascarenhas, PW Thomas, CX Wu, BP Nocek, QQ Hoang, D Liu, ... Biochemistry 54 (28), 4342-4353, 2015 | 23 | 2015 |
An Interprotein Co–S Coordination Complex in the B12-Trafficking Pathway Z Li, R Mascarenhas, UT Twahir, A Kallon, A Deb, M Yaw, J Penner-Hahn, ... Journal of the American Chemical Society 142 (38), 16334-16345, 2020 | 21 | 2020 |
Selective targeting by a mechanism-based inactivator against pyridoxal 5′-phosphate-dependent enzymes: Mechanisms of inactivation and alternative turnover R Mascarenhas, HV Le, KD Clevenger, HJ Lehrer, D Ringe, NL Kelleher, ... Biochemistry 56 (37), 4951-4961, 2017 | 20 | 2017 |
The human B12 trafficking protein CblC processes nitrocobalamin R Mascarenhas, Z Li, C Gherasim, M Ruetz, R Banerjee Journal of Biological Chemistry 295 (28), 9630-9640, 2020 | 19 | 2020 |
Mobile loop dynamics in adenosyltransferase control binding and reactivity of coenzyme B12 R Mascarenhas, M Ruetz, L McDevitt, M Koutmos, R Banerjee Proceedings of the National Academy of Sciences 117 (48), 30412-30422, 2020 | 16 | 2020 |
Human B12-dependent enzymes: Methionine synthase and Methylmalonyl-CoA mutase R Mascarenhas, H Gouda, M Ruetz, R Banerjee Methods in enzymology 668, 309-326, 2022 | 11 | 2022 |
Structural analysis reveals a pyruvate-binding activator site in the Agrobacterium tumefaciens ADP–glucose pyrophosphorylase BL Hill, R Mascarenhas, HP Patel, MDA Diez, R Wu, AA Iglesias, D Liu, ... Journal of Biological Chemistry 294 (4), 1338-1348, 2019 | 10 | 2019 |
Substrate trapping in the siderophore tailoring enzyme PvdQ KD Clevenger, R Mascarenhas, D Catlin, R Wu, NL Kelleher, EJ Drake, ... ACS chemical biology 12 (3), 643-647, 2017 | 9 | 2017 |
On the simultaneous activation of Agrobacterium tumefaciens ADP-glucose pyrophosphorylase by pyruvate and fructose 6-phosphate MDA Diez, CM Figueroa, MC Esper, R Mascarenhas, MC Aleanzi, D Liu, ... Biochimie 171, 23-30, 2020 | 5 | 2020 |
Disease-causing cystathionine β-synthase linker mutations impair allosteric regulation JV Roman, R Mascarenhas, K Ceric, DP Ballou, R Banerjee Journal of Biological Chemistry 299 (12), 2023 | 3 | 2023 |
Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B12 repair H Gouda, R Mascarenhas, M Ruetz, M Yaw, R Banerjee Proceedings of the National Academy of Sciences 120 (11), e2220677120, 2023 | 3 | 2023 |
Cyclobutanone inhibitor of cobalt-functionalized metallo-γ-lactonase AiiA with cyclobutanone ring opening in the active site CT Reidl, R Mascarenhas, TSH Mohammad, MR Lutz Jr, PW Thomas, ... ACS omega 6 (21), 13567-13578, 2021 | 3 | 2021 |
Patient mutations in human ATP: cob (I) alamin adenosyltransferase differentially affect its catalytic versus chaperone functions H Gouda, R Mascarenhas, S Pillay, M Ruetz, M Koutmos, R Banerjee Journal of Biological Chemistry 297 (6), 2021 | 2 | 2021 |
Cobalt–Sulfur Coordination Chemistry Drives B12 Loading onto Methionine Synthase R Mascarenhas, A Guha, Z Li, M Ruetz, S An, J Seravalli, R Banerjee Journal of the American Chemical Society 145 (45), 24678-24689, 2023 | 1 | 2023 |
Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B12 delivery and repair R Mascarenhas, M Ruetz, H Gouda, N Heitman, M Yaw, R Banerjee Nature Communications 14 (1), 4332, 2023 | 1 | 2023 |
The impact of patient mutations on coenzyme B12 loading and repair M Ruetz, R Mascarenhas, H Gouda, N Heitman, R Banerjee Journal of Biological Chemistry 299 (3), S336, 2023 | | 2023 |
Human Methionine B12-dependent synthase enzymes: and Methylmalonyl-CoA mutase R Mascarenhas, H Gouda, M Ruetz, R Banerjee Coenzyme B12 Enzymes Part A, 309, 2022 | | 2022 |
Reply to Sysel et al.: Comment on the importance of using nitric oxide gas in the synthesis of nitrosylcobalamin and ICH-validated methods to assess purity and stability R Mascarenhas, Z Li, C Gherasim, M Ruetz, R Banerjee The Journal of Biological Chemistry 295 (43), 14790, 2020 | | 2020 |
Interprotein Co–S Coordination Complex in the B₁₂-Trafficking Pathway Z Li, R Mascarenhas, UT Twahir, A Kallon, A Deb, M Yaw, J Penner-Hahn, ... | | 2020 |