| Aggregation-prone c9FTD/ALS poly (GA) RAN-translated proteins cause neurotoxicity by inducing ER stress YJ Zhang, K Jansen-West, YF Xu, TF Gendron, KF Bieniek, WL Lin, ... Acta neuropathologica 128, 505-524, 2014 | 383 | 2014 |
| Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS M Prudencio, VV Belzil, R Batra, CA Ross, TF Gendron, LJ Pregent, ... Nature neuroscience 18 (8), 1175-1182, 2015 | 379 | 2015 |
| Discovery of a biomarker and lead small molecules to target r (GGGGCC)-associated defects in c9FTD/ALS Z Su, Y Zhang, TF Gendron, PO Bauer, J Chew, WY Yang, E Fostvedt, ... Neuron 83 (5), 1043-1050, 2014 | 370 | 2014 |
| Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood VV Belzil, PO Bauer, M Prudencio, TF Gendron, CT Stetler, IK Yan, ... Acta neuropathologica 126, 895-905, 2013 | 337 | 2013 |
| Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis TF Gendron, J Chew, JN Stankowski, LR Hayes, YJ Zhang, M Prudencio, ... Science translational medicine 9 (383), eaai7866, 2017 | 223 | 2017 |
| Exome sequencing identifies FUS mutations as a cause of essential tremor ND Merner, SL Girard, H Catoire, CV Bourassa, VV Belzil, JB Rivière, ... The American Journal of Human Genetics 91 (2), 313-319, 2012 | 208 | 2012 |
| Mutations in FUS cause FALS and SALS in French and French Canadian populations VV Belzil, PN Valdmanis, PA Dion, H Daoud, E Kabashi, A Noreau, ... Neurology 73 (15), 1176-1179, 2009 | 178 | 2009 |
| ERBB4 mutations that disrupt the neuregulin-ErbB4 pathway cause amyotrophic lateral sclerosis type 19 Y Takahashi, Y Fukuda, J Yoshimura, A Toyoda, K Kurppa, H Moritoyo, ... The American Journal of Human Genetics 93 (5), 900-905, 2013 | 169 | 2013 |
| Mechanisms of toxicity in C9FTLD/ALS TF Gendron, VV Belzil, YJ Zhang, L Petrucelli Acta neuropathologica 127, 359-376, 2014 | 160 | 2014 |
| Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight MTW Ebbert, TD Jensen, K Jansen-West, JP Sens, JS Reddy, PG Ridge, ... Genome biology 20, 1-23, 2019 | 152 | 2019 |
| Deleterious mutations in the essential mRNA metabolism factor, hGle1, in amyotrophic lateral sclerosis HM Kaneb, AW Folkmann, VV Belzil, LE Jao, CS Leblond, SL Girard, ... Human molecular genetics 24 (5), 1363-1373, 2015 | 148 | 2015 |
| Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts NJ Kramer, Y Carlomagno, YJ Zhang, S Almeida, CN Cook, TF Gendron, ... Science 353 (6300), 708-712, 2016 | 132 | 2016 |
| Association of long ATXN2 CAG repeat sizes with increased risk of amyotrophic lateral sclerosis H Daoud, V Belzil, S Martins, M Sabbagh, P Provencher, L Lacomblez, ... Archives of neurology 68 (6), 739-742, 2011 | 123 | 2011 |
| Exome sequencing reveals SPG11 mutations causing juvenile ALS H Daoud, S Zhou, A Noreau, M Sabbagh, V Belzil, A Dionne-Laporte, ... Neurobiology of aging 33 (4), 839. e5-839. e9, 2012 | 116 | 2012 |
| Phenotype and genotype analysis in amyotrophic lateral sclerosis with TARDBP gene mutations P Corcia, P Valdmanis, S Millecamps, C Lionnet, H Blasco, K Mouzat, ... Neurology 78 (19), 1519-1526, 2012 | 110 | 2012 |
| Characterization of DNA hypermethylation in the cerebellum of c9FTD/ALS patients VV Belzil, PO Bauer, TF Gendron, ME Murray, D Dickson, L Petrucelli Brain research 1584, 15-21, 2014 | 104 | 2014 |
| RNA-mediated toxicity in neurodegenerative disease VV Belzil, TF Gendron, L Petrucelli Molecular and Cellular Neuroscience 56, 406-419, 2013 | 101 | 2013 |
| ALS and FTD: an epigenetic perspective VV Belzil, RB Katzman, L Petrucelli Acta neuropathologica 132, 487-502, 2016 | 83 | 2016 |
| Analysis of OPTN as a causative gene for amyotrophic lateral sclerosis VV Belzil, H Daoud, A Desjarlais, JP Bouchard, N Dupré, W Camu, ... Neurobiology of aging 32 (3), 555. e13-555. e14, 2011 | 72 | 2011 |
| ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD S Moore, E Alsop, I Lorenzini, A Starr, BE Rabichow, E Mendez, JL Levy, ... Acta neuropathologica 138, 49-65, 2019 | 62 | 2019 |
