Paul T. Edlefsen
Paul T. Edlefsen
Assistant Member, Biostatistics, Bioinformatics and Epidemiology Program, Vaccine and Infectious
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Immune clearance of highly pathogenic SIV infection
SG Hansen, M Piatak Jr, AB Ventura, CM Hughes, RM Gilbride, JC Ford, ...
Nature 502 (7469), 100-104, 2013
Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection
TA Wagner, S McLaughlin, K Garg, CYK Cheung, BB Larsen, S Styrchak, ...
Science 345 (6196), 570-573, 2014
Cytomegalovirus vectors violate CD8+ T cell epitope recognition paradigms
SG Hansen, JB Sacha, CM Hughes, JC Ford, BJ Burwitz, I Scholz, ...
Science 340 (6135), 2013
Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2
M Rolland, PT Edlefsen, BB Larsen, S Tovanabutra, E Sanders-Buell, ...
Nature 490 (7420), 417-420, 2012
B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers
Y Fukazawa, R Lum, AA Okoye, H Park, K Matsuda, JY Bae, SI Hagen, ...
Nature medicine 21 (2), 132-139, 2015
Global panel of HIV-1 Env reference strains for standardized assessments of vaccine-elicited neutralizing antibodies
A deCamp, P Hraber, RT Bailer, MS Seaman, C Ochsenbauer, J Kappes, ...
Journal of virology 88 (5), 2489-2507, 2014
Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines
Y Fukazawa, H Park, MJ Cameron, F Lefebvre, R Lum, N Coombes, ...
Nature medicine 18 (11), 1673-1681, 2012
Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine
SG Hansen, DE Zak, G Xu, JC Ford, EE Marshall, D Malouli, RM Gilbride, ...
Nature medicine 24 (2), 130-143, 2018
Global profiling of Shewanella oneidensis MR-1: expression of hypothetical genes and improved functional annotations
E Kolker, AF Picone, MY Galperin, MF Romine, R Higdon, KS Makarova, ...
Proceedings of the National Academy of Sciences 102 (6), 2099-2104, 2005
FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial
SS Li, PB Gilbert, GD Tomaras, G Kijak, G Ferrari, R Thomas, CW Pyo, ...
The Journal of clinical investigation 124 (9), 3879-3890, 2014
Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound
AA Okoye, SG Hansen, M Vaidya, Y Fukazawa, H Park, DM Duell, R Lum, ...
Nature medicine 24 (9), 1430-1440, 2018
Analysis of HLA A* 02 association with vaccine efficacy in the RV144 HIV-1 vaccine trial
AJ Gartland, S Li, J McNevin, GD Tomaras, R Gottardo, H Janes, Y Fong, ...
Journal of virology 88 (15), 8242-8255, 2014
Comprehensive sieve analysis of breakthrough HIV-1 sequences in the RV144 vaccine efficacy trial
PT Edlefsen, M Rolland, T Hertz, S Tovanabutra, AJ Gartland, ...
PLoS computational biology 11 (2), e1003973, 2015
Vaccine-induced human antibodies specific for the third variable region of HIV-1 gp120 impose immune pressure on infecting viruses
S Zolla-Pazner, PT Edlefsen, M Rolland, XP Kong, A deCamp, R Gottardo, ...
EBioMedicine 1 (1), 37-45, 2014
A live-attenuated RhCMV/SIV vaccine shows long-term efficacy against heterologous SIV challenge
SG Hansen, EE Marshall, D Malouli, AB Ventura, CM Hughes, E Ainslie, ...
Science translational medicine 11 (501), 2019
Viral genetic diversity and protective efficacy of a tetravalent dengue vaccine in two phase 3 trials
M Juraska, CA Magaret, J Shao, LN Carpp, AJ Fiore-Gartland, ...
Proceedings of the National Academy of Sciences 115 (36), E8378-E8387, 2018
Sieve analysis in HIV-1 vaccine efficacy trials
PT Edlefsen, PB Gilbert, M Rolland
Current opinion in HIV and AIDS 8 (5), 2013
Addendum: Immune clearance of highly pathogenic SIV infection
SG Hansen, M Piatak, AB Ventura, CM Hughes, RM Gilbride, JC Ford, ...
Nature 547 (7661), 123-124, 2017
Early cellular innate immune responses drive Zika viral persistence and tissue tropism in pigtail macaques
MA O’Connor, J Tisoncik-Go, TB Lewis, CJ Miller, D Bratt, CR Moats, ...
Nature communications 9 (1), 1-11, 2018
Sieve analysis of breakthrough HIV-1 sequences in HVTN 505 identifies vaccine pressure targeting the CD4 binding site of Env-gp120
AC Decamp, M Rolland, PT Edlefsen, E Sanders-Buell, B Hall, ...
PloS one 12 (11), e0185959, 2017
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