| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10745 | 2021 |
| Nanoparticle biointerfacing by platelet membrane cloaking CMJ Hu, RH Fang, KC Wang, BT Luk, S Thamphiwatana, D Dehaini, ... Nature 526 (7571), 118-121, 2015 | 1446 | 2015 |
| Molecular basis of the effects of shear stress on vascular endothelial cells YSJ Li, JH Haga, S Chien Journal of biomechanics 38 (10), 1949-1971, 2005 | 1162 | 2005 |
| Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux Q Wang, Y Zhang, C Yang, H Xiong, Y Lin, J Yao, H Li, L Xie, W Zhao, ... Science 327 (5968), 1004-1007, 2010 | 1115 | 2010 |
| Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy J Kim, YC Kim, C Fang, RC Russell, JH Kim, W Fan, R Liu, Q Zhong, ... Cell 152 (1), 290-303, 2013 | 853 | 2013 |
| mTOR as a central hub of nutrient signalling and cell growth J Kim, KL Guan Nature cell biology 21 (1), 63-71, 2019 | 850 | 2019 |
| The Hippo pathway: biology and pathophysiology S Ma, Z Meng, R Chen, KL Guan Annual review of biochemistry 88, 577-604, 2019 | 845 | 2019 |
| AMPK and mTOR in cellular energy homeostasis and drug targets K Inoki, J Kim, KL Guan Annual review of pharmacology and toxicology 52, 381-400, 2012 | 843 | 2012 |
| Piezo1, a mechanically activated ion channel, is required for vascular development in mice SS Ranade, Z Qiu, SH Woo, SS Hur, SE Murthy, SM Cahalan, J Xu, ... Proceedings of the National Academy of Sciences 111 (28), 10347-10352, 2014 | 822 | 2014 |
| Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting X Ma, X Qu, W Zhu, YS Li, S Yuan, H Zhang, J Liu, P Wang, CSE Lai, ... Proceedings of the National Academy of Sciences 113 (8), 2206-2211, 2016 | 814 | 2016 |
| The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation I Lian, J Kim, H Okazawa, J Zhao, B Zhao, J Yu, A Chinnaiyan, MA Israel, ... Genes & development 24 (11), 1106-1118, 2010 | 811 | 2010 |
| ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS A Alexander, SL Cai, J Kim, A Nanez, M Sahin, KH MacLean, K Inoki, ... Proceedings of the National Academy of Sciences 107 (9), 4153-4158, 2010 | 790 | 2010 |
| Role of integrins in endothelial mechanosensing of shear stress JYJ Shyy, S Chien Circulation research 91 (9), 769-775, 2002 | 765 | 2002 |
| Autophagy regulation by nutrient signaling RC Russell, HX Yuan, KL Guan Cell research 24 (1), 42-57, 2014 | 763 | 2014 |
| TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species C Chen, Y Liu, R Liu, T Ikenoue, KL Guan, Y Liu, P Zheng The Journal of experimental medicine 205 (10), 2397-2408, 2008 | 759 | 2008 |
| Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling T Ikenoue, K Inoki, Q Yang, X Zhou, KL Guan The EMBO journal 27 (14), 1919-1931, 2008 | 757 | 2008 |
| Mechanotransduction in response to shear stress: roles of receptor tyrosine kinases, integrins, and Shc KD Chen, YS Li, M Kim, S Li, S Yuan, S Chien, JYJ Shyy Journal of Biological Chemistry 274 (26), 18393-18400, 1999 | 740 | 1999 |
| Expanding mTOR signaling Q Yang, KL Guan Cell research 17 (8), 666-681, 2007 | 735 | 2007 |
| Protein Tyrosine Phosphatase Activity of an Essential Virulence Determinant in Yersinia K Guan, JE Dixon Science 249 (4968), 553-556, 1990 | 725 | 1990 |
| Activation of integrins in endothelial cells by fluid shear stress mediates Rho‐dependent cytoskeletal alignment E Tzima, MA Del Pozo, SJ Shattil, S Chien, MA Schwartz The EMBO journal, 2001 | 722 | 2001 |
