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Shridhar Bale
Shridhar Bale
Staff Scientist
Adresse e-mail validée de scripps.edu
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Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase
A Chatterjee, ND Abeydeera, S Bale, PJ Pai, PC Dorrestein, DH Russell, ...
Nature 478 (7370), 542-546, 2011
270*2011
Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design
SK Sharma, N de Val, S Bale, J Guenaga, K Tran, Y Feng, V Dubrovskaya, ...
Cell reports 11 (4), 539-550, 2015
2362015
A shared structural solution for neutralizing ebolaviruses
JM Dias, AI Kuehne, DM Abelson, S Bale, AC Wong, P Halfmann, ...
Nature structural & molecular biology 18 (12), 1424-1427, 2011
1502011
Crystal Structure and Mechanism of Tryptophan 2,3-Dioxygenase, a Heme Enzyme Involved in Tryptophan Catabolism and in Quinolinate Biosynthesis,
Y Zhang, SA Kang, T Mukherjee, S Bale, BR Crane, TP Begley, SE Ealick
Biochemistry 46 (1), 145-155, 2007
1392007
Vaccination with glycan-modified HIV NFL envelope trimer-liposomes elicits broadly neutralizing antibodies to multiple sites of vulnerability
V Dubrovskaya, K Tran, G Ozorowski, J Guenaga, R Wilson, S Bale, ...
Immunity 51 (5), 915-929. e7, 2019
1202019
Host-primed Ebola virus GP exposes a hydrophobic NPC1 receptor-binding pocket, revealing a target for broadly neutralizing antibodies
ZA Bornholdt, E Ndungo, ML Fusco, S Bale, AI Flyak, JE Crowe Jr, ...
MBio 7 (1), 10.1128/mbio. 02154-15, 2016
1102016
Particulate array of well-ordered HIV clade C Env trimers elicits neutralizing antibodies that display a unique V2 cap approach
P Martinez-Murillo, K Tran, J Guenaga, G Lindgren, M Àdori, Y Feng, ...
Immunity 46 (5), 804-817. e7, 2017
1022017
Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism
S Bale, JP Julien, ZA Bornholdt, CR Kimberlin, P Halfmann, ...
Public Library of Science 8 (9), e1002916, 2012
892012
Thermostability of well-ordered HIV spikes correlates with the elicitation of autologous tier 2 neutralizing antibodies
Y Feng, K Tran, S Bale, S Kumar, J Guenaga, R Wilson, N de Val, ...
PLoS pathogens 12 (8), e1005767, 2016
852016
Ebola virus glycoprotein needs an additional trigger, beyond proteolytic priming for membrane fusion
S Bale, T Liu, S Li, Y Wang, D Abelson, M Fusco, VL Woods Jr, ...
PLoS neglected tropical diseases 5 (11), e1395, 2011
832011
Structural basis for differential neutralization of ebolaviruses
S Bale, JM Dias, ML Fusco, T Hashiguchi, AC Wong, T Liu, AI Keuhne, ...
Viruses 4 (4), 447-470, 2012
822012
Covalent linkage of HIV-1 trimers to synthetic liposomes elicits improved B cell and antibody responses
S Bale, G Goebrecht, A Stano, R Wilson, T Ota, K Tran, J Ingale, MB Zwick, ...
Journal of virology 91 (16), 10.1128/jvi. 00443-17, 2017
782017
Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism
S Bale, JP Julien, ZA Bornholdt, AS Krois, IA Wilson, EO Saphire
Journal of virology 87 (18), 10385-10388, 2013
672013
Structural biology of S-adenosylmethionine decarboxylase
S Bale, SE Ealick
Amino acids 38, 451-460, 2010
652010
Structural Similarities between Thiamin-Binding Protein and Thiaminase-I Suggest a Common Ancestor,
EV Soriano, KR Rajashankar, JW Hanes, S Bale, TP Begley, SE Ealick
Biochemistry 47 (5), 1346-1357, 2008
562008
Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer
A Sarkar, S Bale, AJ Behrens, S Kumar, SK Sharma, N de Val, J Pallesen, ...
Nature communications 9 (1), 1956, 2018
502018
Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase
S Bale, MM Lopez, GI Makhatadze, Q Fang, AE Pegg, SE Ealick
Biochemistry 47 (50), 13404-13417, 2008
492008
Structure of an antibody in complex with its mucin domain linear epitope that is protective against Ebola virus
D Olal, AI Kuehne, S Bale, P Halfmann, T Hashiguchi, ML Fusco, JE Lee, ...
Journal of virology 86 (5), 2809-2816, 2012
482012
Hiding the evidence: two strategies for innate immune evasion by hemorrhagic fever viruses
KM Hastie, S Bale, CR Kimberlin, EO Saphire
Current opinion in virology 2 (2), 151-156, 2012
462012
Two synthetic antibodies that recognize and neutralize distinct proteolytic forms of the ebola virus envelope glycoprotein
JF Koellhoffer, G Chen, RG Sandesara, S Bale, E Ollmann Saphire, ...
Chembiochem 13 (17), 2549-2557, 2012
412012
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