Suivre
Hamlet Chu
Hamlet Chu
Cancer biology and Immunology research
Adresse e-mail validée de exelixis.com
Titre
Citée par
Citée par
Année
Naive CD4+ T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude
JJ Moon, HH Chu, M Pepper, SJ McSorley, SC Jameson, RM Kedl, ...
Immunity 27 (2), 203-213, 2007
11152007
Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire
MA Burchill, J Yang, KB Vang, JJ Moon, HH Chu, CWJ Lio, AL Vegoe, ...
Immunity 28 (1), 112-121, 2008
5112008
Tracking epitope-specific T cells
JJ Moon, HH Chu, J Hataye, AJ Pagán, M Pepper, JB McLachlan, T Zell, ...
Nature protocols 4 (4), 565-581, 2009
3322009
On the composition of the preimmune repertoire of T cells specific for peptide–major histocompatibility complex ligands
MK Jenkins, HH Chu, JB McLachlan, JJ Moon
Annual review of immunology 28, 275-294, 2009
2892009
Quantitative impact of thymic selection on Foxp3+ and Foxp3 subsets of self-peptide/MHC class II-specific CD4+ T cells
JJ Moon, P Dash, TH Oguin III, JL McClaren, HH Chu, PG Thomas, ...
Proceedings of the National Academy of Sciences 108 (35), 14602-14607, 2011
1272011
Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain
E Gagnon, DA Schubert, S Gordo, HH Chu, KW Wucherpfennig
Journal of Experimental Medicine 209 (13), 2423-2439, 2012
1132012
Continuous effector CD8+ T cell production in a controlled persistent infection is sustained by a proliferative intermediate population
HH Chu, SW Chan, JP Gosling, N Blanchard, A Tsitsiklis, G Lythe, ...
Immunity 45 (1), 159-171, 2016
772016
Location of the CD8 T Cell Epitope within the Antigenic Precursor Determines Immunogenicity and Protection against the Toxoplasma gondii Parasite
V Feliu, V Vasseur, HS Grover, HH Chu, MJ Brown, J Wang, JP Boyle, ...
PLoS pathogens 9 (6), e1003449, 2013
652013
Dendritic cells amplify T cell-mediated immune responses in the central nervous system
J Karman, HH Chu, DO Co, CM Seroogy, M Sandor, Z Fabry
The Journal of Immunology 177 (11), 7750-7760, 2006
542006
Negative selection and peptide chemistry determine the size of naive foreign peptide–MHC class II-specific CD4+ T cell populations
HH Chu, JJ Moon, AC Kruse, M Pepper, MK Jenkins
The Journal of immunology 185 (8), 4705-4713, 2010
532010
Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire
HH Chu, JJ Moon, K Takada, M Pepper, JA Molitor, TW Schacker, ...
Proceedings of the National Academy of Sciences 106 (27), 11241-11245, 2009
512009
CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs
AJ Pagán, M Pepper, HH Chu, JM Green, MK Jenkins
The Journal of immunology 189 (6), 2909-2917, 2012
432012
The transcription factors Thpok and LRF are necessary and partly redundant for T helper cell differentiation
AC Carpenter, JR Grainger, Y Xiong, Y Kanno, HH Chu, L Wang, S Naik, ...
Immunity 37 (4), 622-633, 2012
422012
Response multilayered control of T cell receptor phosphorylation
E Gagnon, C Xu, W Yang, HH Chu, ME Call, JJ Chou, KW Wucherpfennig
Cell 142 (5), 669-671, 2010
402010
TCR ITAM multiplicity is required for the generation of follicular helper T-cells
SJ Hwang, AC Palin, LQ Li, KD Song, J Lee, J Herz, N Tubo, H Chu, ...
Nature communications 6 (1), 6982, 2015
392015
Impact of regulated secretion on antiparasitic CD8 T cell responses
HS Grover, HH Chu, FD Kelly, SJ Yang, ML Reese, N Blanchard, ...
Cell reports 7 (5), 1716-1728, 2014
302014
Naive CD4 (+) T cell frequency varies for different application to human mitochondrial DNA restriction data
JJ Moon, HH Chu, M Pepper, SJ McSorley, SC Jameson, RM Kedl, ...
Genetics 131, 479-491, 2007
222007
The same well-characterized T cell epitope SIINFEKL expressed in the context of a cytoplasmic or secreted protein in BCG induces different CD8+ T cell responses
PD Hulseberg, A Zozulya, HH Chu, JA Triccas, Z Fabry, M Sandor
Immunology letters 130 (1-2), 36-42, 2010
162010
847 Pharmacokinetics and pharmacodynamics of GS-3583 in cynomolgus monkeys
M Kuhne, H Chu, C Clarke, B Carr, M Baca, M Hung, M Nagel, ...
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A888-A888, 2021
12021
846 Pre-clinical validation of a FLT3L-fusion protein for dendritic cell expansion and anti-tumor efficacy
M Kuhne, H Chu, S Ng, C Clarke, B Carr, M Baca, M Hung, M Nagel, ...
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A887-A887, 2021
12021
Le système ne peut pas réaliser cette opération maintenant. Veuillez réessayer plus tard.
Articles 1–20