| Flavin-dependent enzymes RL Fagan, BA Palfey Comprehensive natural products II 7, 37-113, 2010 | 127* | 2010 |
| The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1 F Syeda, RL Fagan, M Wean, GV Avvakumov, JR Walker, S Xue, ... Journal of Biological Chemistry 286 (17), 15344-15351, 2011 | 126 | 2011 |
| Oxygen reactivity in flavoenzymes: context matters CA McDonald, RL Fagan, F Collard, VM Monnier, BA Palfey Journal of the American Chemical Society 133 (42), 16809-16811, 2011 | 81 | 2011 |
| Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1 RL Fagan, DE Cryderman, L Kopelovich, LL Wallrath, C Brenner Journal of Biological Chemistry 288 (33), 23858-23867, 2013 | 75 | 2013 |
| RGS6 suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 degradation and promoting apoptosis J Huang, A Stewart, B Maity, J Hagen, RL Fagan, J Yang, DE Quelle, ... Oncogene 33 (27), 3604-3611, 2014 | 55 | 2014 |
| Mechanism of flavin reduction in class 2 dihydroorotate dehydrogenases RL Fagan, MN Nelson, PM Pagano, BA Palfey Biochemistry 45 (50), 14926-14932, 2006 | 48 | 2006 |
| Mechanism of flavin reduction in the class 1A dihydroorotate dehydrogenase from Lactococcus lactis RL Fagan, KF Jensen, O Björnberg, BA Palfey Biochemistry 46 (13), 4028-4036, 2007 | 32 | 2007 |
| Roles in binding and chemistry for conserved active site residues in the class 2 dihydroorotate dehydrogenase from Escherichia coli RL Fagan, BA Palfey Biochemistry 48 (30), 7169-7178, 2009 | 27 | 2009 |
| An ultrasensitive high throughput screen for DNA methyltransferase 1-targeted molecular probes RL Fagan, M Wu, F Chédin, C Brenner PloS one 8 (11), e78752, 2013 | 24 | 2013 |
| Interaction of benzoate pyrimidine analogues with class 1A dihydroorotate dehydrogenase from Lactococcus lactis AE Wolfe, M Thymark, SG Gattis, RL Fagan, Y Hu, E Johansson, S Arent, ... Biochemistry 46 (19), 5741-5753, 2007 | 18 | 2007 |
| The Cation− π Interaction between Lys53 and the Flavin of Fructosamine Oxidase (FAOX-II) Is Critical for Activity F Collard, RL Fagan, J Zhang, I Nemet, BA Palfey, VM Monnier Biochemistry 50 (37), 7977-7986, 2011 | 14 | 2011 |
| Substituted anthraquinones represent a potential scaffold for DNA methyltransferase 1-specific inhibitors RL Switzer, J Medrano, DA Reedel, J Weiss PLOS ONE 14 (7), e0219830, 2019 | 13 | 2019 |
| Disruption of the proton relay network in the class 2 dihydroorotate dehydrogenase from Escherichia coli RL Kow, JR Whicher, CA McDonald, BA Palfey, RL Fagan Biochemistry 48 (41), 9801-9809, 2009 | 11 | 2009 |
| Disease-Associated Mutations G589A and V590F Relieve Replication Focus Targeting Sequence-Mediated Autoinhibition of DNA Methyltransferase 1. EK Dolen, JH McGinnis, RN Tavory, JA Weiss, RL Switzer Biochemistry 58 (51), 5151-5159, 2019 | 9 | 2019 |
| Analysis of the kinetic isotope effects on initial rates in transient kinetics BA Palfey, RL Fagan Biochemistry 45 (45), 13631-13640, 2006 | 7 | 2006 |
| Kinetics of Enzyme Catalysis BA Palfey, RL Switzer | 2 | 2022 |
| Disease-Associated Mutation A554V Disrupts Normal Autoinhibition of DNMT1 RL Switzer, ZJ Hartman, GR Hewett, CF Carroll DNA 3 (3), 119-133, 2023 | | 2023 |
| Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors R Switzer, KA Ward, J Medrano JoVE (Journal of Visualized Experiments), e62949, 2022 | | 2022 |
| Therapeutic Compounds CM Brenner, RL Fagan US Patent App. 13/774,594, 2013 | | 2013 |
| webZyme–A Web-Based Enzyme Simulation System for Education and Research RL Fagan, B Haber, BA Palfey Flavins and Flavoproteins 2008, 601 – 607, 2008 | | 2008 |
Bruce A. PalfeyAssociate Professor of Biological Chemistry, University of MichiganVerified email at umich.edu
