Alex Toker
Alex Toker
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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3, 4-bisphosphate
TF Franke, DR Kaplan, LC Cantley, A Toker
Science 275 (5300), 665-668, 1997
Signalling through the lipid products of phosphoinositide-3-OH kinase
A Toker, LC Cantley
Nature 387 (6634), 673-676, 1997
AKT/PKB signaling: navigating the network
BD Manning, A Toker
Cell 169 (3), 381-405, 2017
Sequence analysis of mutations and translocations across breast cancer subtypes
S Banerji, K Cibulskis, C Rangel-Escareno, KK Brown, SL Carter, ...
Nature 486 (7403), 405-409, 2012
Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets
JH Hartwig, GM Bokoch, CL Carpenter, PA Janmey, LA Taylor, A Toker, ...
Cell 82 (4), 643-653, 1995
Regulation of protein kinase C ζ by PI 3-kinase and PDK-1
MM Chou, W Hou, J Johnson, LK Graham, MH Lee, CS Chen, AC Newton, ...
Current Biology 8 (19), 1069-1078, 1998
Activation of phosphoinositide 3-OH kinase by the α6β4 integrin promotes carcinoma invasion
LM Shaw, I Rabinovitz, HHF Wang, A Toker, AM Mercurio
Cell 91 (7), 949-960, 1997
Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3, 4-P2 and PtdIns-3, 4, 5-P3.
A Toker, M Meyer, KK Reddy, JR Falck, R Aneja, S Aneja, A Parra, ...
Journal of Biological Chemistry 269 (51), 32358-32367, 1994
Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site
A Toker, AC Newton
Journal of Biological Chemistry 275 (12), 8271-8274, 2000
Determination of the specific substrate sequence motifs of protein kinase C isozymes
K Nishikawa, A Toker, FJ Johannes, Z Songyang, LC Cantley
Journal of Biological Chemistry 272 (2), 952-960, 1997
Cellular signaling: pivoting around PDK-1
A Toker, AC Newton
Cell 103 (2), 185-188, 2000
Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)
EM Dutil, A Toker, AC Newton
Current Biology 8 (25), 1366-1375, 1998
A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans
S Paradis, M Ailion, A Toker, JH Thomas, G Ruvkun
Genes & development 13 (11), 1438-1452, 1999
Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT
M Yoeli-Lerner, GK Yiu, I Rabinovitz, P Erhardt, S Jauliac, A Toker
Molecular cell 20 (4), 539-550, 2005
The role of NFAT transcription factors in integrin-mediated carcinoma invasion
S Jauliac, C López-Rodriguez, LM Shaw, LF Brown, A Rao, A Toker
Nature cell biology 4 (7), 540-544, 2002
Signaling through protein kinase C
A Toker
Front Biosci 3 (1), 1134-47, 1998
Protein kinases as mediators of phosphoinositide 3-kinase signaling
A Toker
Molecular Pharmacology 57 (4), 652-658, 2000
Akt signaling and cancer: surviving but not moving on
A Toker, M Yoeli-Lerner
Cancer research 66 (8), 3963-3966, 2006
A rapid method for determining protein kinase phosphorylation specificity
JE Hutti, ET Jarrell, JD Chang, DW Abbott, P Storz, A Toker, LC Cantley, ...
Nature methods 1 (1), 27-29, 2004
The synthesis and cellular roles of phosphatidylinositol 4, 5-bisphosphate
A Toker
Current opinion in cell biology 10 (2), 254-261, 1998
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