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Sebastian Kreiter
Sebastian Kreiter
TRON Translational Oncology Mainz
Adresse e-mail validée de tron-mainz.de - Page d'accueil
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Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
U Sahin, E Derhovanessian, M Miller, BP Kloke, P Simon, M Löwer, ...
Nature 547 (7662), 222-226, 2017
21532017
Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
LM Kranz, M Diken, H Haas, S Kreiter, C Loquai, KC Reuter, M Meng, ...
Nature 534 (7607), 396-401, 2016
14892016
Mutant MHC class II epitopes drive therapeutic immune responses to cancer
S Kreiter, M Vormehr, N Van de Roemer, M Diken, M Löwer, J Diekmann, ...
Nature 520 (7549), 692-696, 2015
12712015
Cancer classification using the Immunoscore: a worldwide task force
J Galon, F Pagès, FM Marincola, HK Angell, M Thurin, A Lugli, I Zlobec, ...
Journal of translational medicine 10, 1-10, 2012
9432012
Exploiting the mutanome for tumor vaccination
JC Castle, S Kreiter, J Diekmann, M Löwer, N Van de Roemer, J de Graaf, ...
Cancer research 72 (5), 1081-1091, 2012
9192012
Actively personalized vaccination trial for newly diagnosed glioblastoma
N Hilf, S Kuttruff-Coqui, K Frenzel, V Bukur, S Stevanović, ...
Nature 565 (7738), 240-245, 2019
7322019
Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells
S Holtkamp, S Kreiter, A Selmi, P Simon, M Koslowski, C Huber, ...
Blood 108 (13), 4009-4017, 2006
6742006
An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma
U Sahin, P Oehm, E Derhovanessian, RA Jabulowsky, M Vormehr, ...
Nature 585 (7823), 107-112, 2020
6162020
Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity
S Kreiter, A Selmi, M Diken, M Koslowski, CM Britten, C Huber, Ö Türeci, ...
Cancer research 70 (22), 9031-9040, 2010
3902010
Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma
JC Castle, M Loewer, S Boegel, J de Graaf, C Bender, AD Tadmor, ...
BMC genomics 15, 1-12, 2014
3762014
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
C Krienke, L Kolb, E Diken, M Streuber, S Kirchhoff, T Bukur, ...
Science 371 (6525), 145-153, 2021
2912021
Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo
AN Kuhn, M Diken, S Kreiter, A Selmi, J Kowalska, J Jemielity, ...
Gene therapy 17 (8), 961-971, 2010
2502010
Tumor vaccination using messenger RNA: prospects of a future therapy
S Kreiter, M Diken, A Selmi, Ö Türeci, U Sahin
Current opinion in immunology 23 (3), 399-406, 2011
2312011
Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation
M Diken, S Kreiter, A Selmi, CM Britten, C Huber, Ö Türeci, U Sahin
Gene therapy 18 (7), 702-708, 2011
1972011
Increased antigen presentation efficiency by coupling antigens to MHC class I trafficking signals
S Kreiter, A Selmi, M Diken, M Sebastian, P Osterloh, H Schild, C Huber, ...
The Journal of Immunology 180 (1), 309-318, 2008
1822008
Individualized vaccines for cancer
U Sahin, S Kreiter, M Diken, J Diekmann, M Koslowski, C Britten, ...
US Patent 10,738,355, 2020
1662020
Targeting the heterogeneity of cancer with individualized neoepitope vaccines
Ö Türeci, M Vormehr, M Diken, S Kreiter, C Huber, U Sahin
Clinical Cancer Research 22 (8), 1885-1896, 2016
1542016
Modification of RNA, producing an increased transcript stability and translation efficiency
U Sahin, S Holtkamp, Ö Türeci, S Kreiter
US Patent 9,476,055, 2016
1092016
Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models
C Hotz, TR Wagenaar, F Gieseke, DS Bangari, M Callahan, H Cao, ...
Science translational medicine 13 (610), eabc7804, 2021
872021
FLT3 ligand enhances the cancer therapeutic potency of naked RNA vaccines
S Kreiter, M Diken, A Selmi, J Diekmann, S Attig, Y Hüsemann, ...
Cancer research 71 (19), 6132-6142, 2011
872011
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