| PERIOD2:: LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues SH Yoo, S Yamazaki, PL Lowrey, K Shimomura, CH Ko, ED Buhr, ... Proceedings of the National Academy of Sciences 101 (15), 5339-5346, 2004 | 2600 | 2004 |
| Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes B Marcheva, KM Ramsey, ED Buhr, Y Kobayashi, H Su, CH Ko, G Ivanova, ... Nature 466 (7306), 627-631, 2010 | 1663 | 2010 |
| Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis KM Ramsey, J Yoshino, CS Brace, D Abrassart, Y Kobayashi, B Marcheva, ... Science 324 (5927), 651-654, 2009 | 1246 | 2009 |
| Temperature as a universal resetting cue for mammalian circadian oscillators ED Buhr, SH Yoo, JS Takahashi science 330 (6002), 379-385, 2010 | 995 | 2010 |
| Molecular components of the Mammalian circadian clock ED Buhr, JS Takahashi Circadian clocks, 3-27, 2013 | 848 | 2013 |
| Intercellular coupling confers robustness against mutations in the SCN circadian clock network AC Liu, DK Welsh, CH Ko, HG Tran, EE Zhang, AA Priest, ED Buhr, ... Cell 129 (3), 605-616, 2007 | 802 | 2007 |
| A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo SH Yoo, CH Ko, PL Lowrey, ED Buhr, E Song, S Chang, OJ Yoo, ... Proceedings of the National Academy of Sciences 102 (7), 2608-2613, 2005 | 374 | 2005 |
| The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase–response curve amplitude MH Vitaterna, CH Ko, AM Chang, ED Buhr, EM Fruechte, A Schook, ... Proceedings of the National Academy of Sciences 103 (24), 9327-9332, 2006 | 271 | 2006 |
| Emergence of noise-induced oscillations in the central circadian pacemaker CH Ko, YR Yamada, DK Welsh, ED Buhr, AC Liu, EE Zhang, MR Ralph, ... PLoS biology 8 (10), e1000513, 2010 | 243 | 2010 |
| Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening Z Chen, SH Yoo, YS Park, KH Kim, S Wei, E Buhr, ZY Ye, HL Pan, ... Proceedings of the National Academy of Sciences 109 (1), 101-106, 2012 | 208 | 2012 |
| Neuropsin (OPN5)-mediated photoentrainment of local circadian oscillators in mammalian retina and cornea ED Buhr, WWS Yue, X Ren, Z Jiang, HWR Liao, X Mei, S Vemaraju, ... Proceedings of the National Academy of Sciences 112 (42), 13093-13098, 2015 | 159 | 2015 |
| Violet-light suppression of thermogenesis by opsin 5 hypothalamic neurons KX Zhang, S D’Souza, BA Upton, S Kernodle, S Vemaraju, G Nayak, ... Nature 585 (7825), 420-425, 2020 | 96 | 2020 |
| Melanopsin and mechanisms of non-visual ocular photoreception T Sexton, E Buhr, RN Van Gelder Journal of Biological Chemistry 287 (3), 1649-1656, 2012 | 96 | 2012 |
| Neuropsin (OPN5) mediates local light-dependent induction of circadian clock genes and circadian photoentrainment in exposed murine skin ED Buhr, S Vemaraju, N Diaz, RA Lang, RN Van Gelder Current Biology 29 (20), 3478-3487. e4, 2019 | 87 | 2019 |
| Period2 3′-UTR and microRNA-24 regulate circadian rhythms by repressing PERIOD2 protein accumulation SH Yoo, S Kojima, K Shimomura, N Koike, ED Buhr, T Furukawa, CH Ko, ... Proceedings of the National Academy of Sciences 114 (42), E8855-E8864, 2017 | 81 | 2017 |
| Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice K Shimomura, V Kumar, N Koike, TK Kim, J Chong, ED Buhr, AR Whiteley, ... elife 2, e00426, 2013 | 72 | 2013 |
| Ocular clocks: adapting mechanisms for eye functions and health MP Felder-Schmittbuhl, ED Buhr, O Dkhissi-Benyahya, D Hicks, ... Investigative ophthalmology & visual science 59 (12), 4856-4870, 2018 | 70 | 2018 |
| An opsin 5–dopamine pathway mediates light-dependent vascular development in the eye MTT Nguyen, S Vemaraju, G Nayak, Y Odaka, ED Buhr, N Alonzo, U Tran, ... Nature cell biology 21 (4), 420-429, 2019 | 66 | 2019 |
| Genetic suppression of the circadian Clock mutation by the melatonin biosynthesis pathway K Shimomura, PL Lowrey, MH Vitaterna, ED Buhr, V Kumar, P Hanna, ... Proceedings of the National Academy of Sciences 107 (18), 8399-8403, 2010 | 65 | 2010 |
| Adaptive thermogenesis in mice is enhanced by opsin 3-dependent adipocyte light sensing G Nayak, KX Zhang, S Vemaraju, Y Odaka, ED Buhr, A Holt-Jones, ... Cell reports 30 (3), 672-686. e8, 2020 | 60 | 2020 |
